| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.103649 |
| VIM | vimentin | 0.0985488 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0964528 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0920841 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.089044 |
| ZNF292 | zinc finger protein 292 | 0.0875743 |
| CENPF | centromere protein F, 350/400kDa | 0.0791267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0741507 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0709558 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0645335 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0643637 |
| NAV2 | neuron navigator 2 | 0.0621292 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0602465 |
| TPX2 | TPX2, microtubule-associated | 0.0575172 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0565181 |
| SETD5 | SET domain containing 5 | 0.0557763 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0515165 |
| NCKAP1 | NCK-associated protein 1 | 0.0514876 |
| HJURP | Holliday junction recognition protein | 0.0513944 |
| ATP13A3 | ATPase type 13A3 | 0.0500433 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0500405 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0491874 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0490235 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.047373 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0465645 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0463583 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.045634 |
| RAI1 | retinoic acid induced 1 | 0.0448733 |
| NGLY1 | N-glycanase 1 | 0.0445299 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0444139 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0432122 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0424409 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0422867 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0417246 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0395761 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0387347 |
| PYGL | phosphorylase, glycogen, liver | 0.0384553 |
| NUP58 | nucleoporin 58 | 0.038066 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0380571 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0380433 |
| TPM4 | tropomyosin 4 | 0.0377861 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0374415 |
| RBM25 | RNA binding motif protein 25 | 0.037144 |
| CEP250 | centrosomal protein 250kDa | 0.0367121 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0361924 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0361267 |
| NBAS | neuroblastoma amplified sequence | 0.035907 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0356968 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0352678 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0349914 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0349605 |
| ENO1 | enolase 1, (alpha) | 0.0347899 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0347642 |
| AREG | amphiregulin | 0.034478 |
| HIP1 | huntingtin interacting protein 1 | 0.034306 |
| TPR | translocated promoter region, nuclear basket protein | 0.0341909 |
| RPS21 | ribosomal protein S21 | 0.0341397 |
| YBX1 | Y box binding protein 1 | 0.0341057 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0336087 |
| NKTR | natural killer cell triggering receptor | 0.0335087 |
| KIAA1958 | KIAA1958 | 0.0333036 |
| RPS6 | ribosomal protein S6 | 0.0327904 |
| KIF18B | kinesin family member 18B | 0.0327724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0322368 |
| RPL35 | ribosomal protein L35 | 0.0322063 |
| YEATS2 | YEATS domain containing 2 | 0.0322022 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0321275 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0318461 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0317346 |
| PCBP2 | poly(rC) binding protein 2 | 0.0315167 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0312172 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0309659 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0308905 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0308718 |
| RPS2 | ribosomal protein S2 | 0.0306061 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.030421 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0303317 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0301652 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0300451 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0295531 |
| LMNB1 | lamin B1 | 0.0294365 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0294111 |
| LDHB | lactate dehydrogenase B | 0.0293425 |
| CUL5 | cullin 5 | 0.0292422 |
| UVRAG | UV radiation resistance associated | 0.0288193 |
| SET | SET nuclear proto-oncogene | 0.0286638 |
| XPO1 | exportin 1 | 0.0284125 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0283319 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0282276 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280138 |
| CEP295 | centrosomal protein 295kDa | 0.0279801 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0278903 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0278899 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0278117 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0275641 |
| AURKA | aurora kinase A | 0.0274297 |
| TTBK2 | tau tubulin kinase 2 | 0.0273506 |
| NCOA6 | nuclear receptor coactivator 6 | 0.027322 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0269599 |
| SEPTIN10 | septin 10 | 0.0266945 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.303148 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.103016 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0879141 |
| TMSB10 | thymosin beta 10 | -0.0841941 |
| HMGA2 | high mobility group AT-hook 2 | -0.0688401 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0606485 |
| EGR1 | early growth response 1 | -0.059921 |
| RPL35A | ribosomal protein L35a | -0.0596495 |
| ANXA2 | annexin A2 | -0.0535316 |
| FTL | ferritin, light polypeptide | -0.053063 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0515838 |
| IGF2 | insulin-like growth factor 2 | -0.0512913 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0479003 |
| VCL | vinculin | -0.0465609 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0459531 |
| RIGI | RNA sensor RIG-I | -0.0459265 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0452634 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0439662 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0425648 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0414135 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0412502 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0403452 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.039161 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0376838 |
| PARD3 | par-3 family cell polarity regulator | -0.0367408 |
| IL6ST | interleukin 6 signal transducer | -0.0365927 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0363987 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0363937 |
| H3-3B | H3.3 histone B | -0.0358245 |
| PRKCA | protein kinase C, alpha | -0.0351293 |
| PRSS23 | protease, serine, 23 | -0.0346341 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0342632 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.034076 |
| AK1 | adenylate kinase 1 | -0.0340372 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0325419 |
| FUS | FUS RNA binding protein | -0.0325268 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0321612 |
| SMYD3 | SET and MYND domain containing 3 | -0.031921 |
| IER3 | immediate early response 3 | -0.0318142 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0317917 |
| RPL32 | ribosomal protein L32 | -0.031261 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0312165 |
| OSMR | oncostatin M receptor | -0.03118 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0311509 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0309636 |
| DTNA | dystrobrevin, alpha | -0.0302998 |
| GLCCI1 | glucocorticoid induced 1 | -0.0301192 |
| NLK | nemo-like kinase | -0.0298285 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0298186 |
| INTS6 | integrator complex subunit 6 | -0.0289682 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.02864 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0285357 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0284749 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0283835 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0282072 |
| ANGPTL4 | angiopoietin-like 4 | -0.0282034 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0280993 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0280678 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0279266 |
| RPS15 | ribosomal protein S15 | -0.0278617 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0278001 |
| HLA-C | major histocompatibility complex, class I, C | -0.0277934 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0276324 |
| PURA | purine-rich element binding protein A | -0.0276231 |
| PHF14 | PHD finger protein 14 | -0.0270505 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0268561 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0267255 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0262664 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0261671 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0258305 |
| TOX2 | TOX high mobility group box family member 2 | -0.0256847 |
| RPL38 | ribosomal protein L38 | -0.0255437 |
| CD44 | CD44 molecule (Indian blood group) | -0.0253601 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.025342 |
| MT1X | metallothionein 1X | -0.0252108 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0251586 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0250649 |
| NALCN | sodium leak channel, non selective | -0.0250643 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250615 |
| PRR16 | proline rich 16 | -0.024971 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0249138 |
| STAG2 | stromal antigen 2 | -0.0247896 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0247514 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.02475 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0246484 |
| S100A9 | S100 calcium binding protein A9 | -0.0246309 |
| CLIC4 | chloride intracellular channel 4 | -0.0246302 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0245954 |
| UBB | ubiquitin B | -0.0244272 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0243684 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0243306 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0243186 |
| TNPO1 | transportin 1 | -0.0243078 |
| KIF13A | kinesin family member 13A | -0.0241134 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0240813 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0240136 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0235194 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0234604 |
| HLA-B | major histocompatibility complex, class I, B | -0.0234375 |
| MYADM | myeloid-associated differentiation marker | -0.023361 |
