| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.102205 |
| MT2A | metallothionein 2A | 0.0845547 |
| ITGA1 | integrin, alpha 1 | 0.0839195 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0813657 |
| CENPF | centromere protein F, 350/400kDa | 0.0753846 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0631764 |
| GOLGA4 | golgin A4 | 0.0622461 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.059466 |
| RPL9 | ribosomal protein L9 | 0.0589922 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0589703 |
| RPL26 | ribosomal protein L26 | 0.0569527 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0560683 |
| RPL37A | ribosomal protein L37a | 0.0549918 |
| PRELID2 | PRELI domain containing 2 | 0.0532223 |
| RPS6 | ribosomal protein S6 | 0.0512264 |
| RPS12 | ribosomal protein S12 | 0.0510524 |
| FAM13A | family with sequence similarity 13, member A | 0.0487775 |
| TMEM165 | transmembrane protein 165 | 0.0472638 |
| AHR | aryl hydrocarbon receptor | 0.047052 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0464929 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0463569 |
| EREG | epiregulin | 0.0462596 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0453211 |
| RPS21 | ribosomal protein S21 | 0.0450547 |
| OGA | O-GlcNAcase | 0.044612 |
| COG5 | component of oligomeric golgi complex 5 | 0.0442842 |
| RPS27 | ribosomal protein S27 | 0.0432372 |
| RNF145 | ring finger protein 145 | 0.0410263 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0409488 |
| RPL30 | ribosomal protein L30 | 0.0406479 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0395273 |
| RPS8 | ribosomal protein S8 | 0.0394989 |
| VIM | vimentin | 0.0394831 |
| B2M | beta-2-microglobulin | 0.0390615 |
| HDGF | hepatoma-derived growth factor | 0.0378832 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0376387 |
| FBXO32 | F-box protein 32 | 0.037305 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0369907 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036196 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0359957 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0358412 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0357923 |
| NKTR | natural killer cell triggering receptor | 0.0357194 |
| RPL18 | ribosomal protein L18 | 0.0349972 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0349149 |
| RPL37 | ribosomal protein L37 | 0.0347909 |
| RPS29 | ribosomal protein S29 | 0.0345814 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0344428 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0344148 |
| RACK1 | receptor for activated C kinase 1 | 0.0341417 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0337286 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0335994 |
| NBAS | neuroblastoma amplified sequence | 0.0335405 |
| TXNIP | thioredoxin interacting protein | 0.0334221 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0333602 |
| RPLP1 | ribosomal protein, large, P1 | 0.0333366 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0326026 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0324478 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0323911 |
| RBM25 | RNA binding motif protein 25 | 0.0320821 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0319374 |
| RAB18 | RAB18, member RAS oncogene family | 0.0318892 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0314825 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0311414 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0311414 |
| RO60 | Ro60, Y RNA binding protein | 0.0309606 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.030853 |
| PTK2 | protein tyrosine kinase 2 | 0.0308473 |
| ZNF292 | zinc finger protein 292 | 0.0306823 |
| TPI1 | triosephosphate isomerase 1 | 0.0304861 |
| NOP58 | NOP58 ribonucleoprotein | 0.0298754 |
| SMOX | spermine oxidase | 0.029705 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0293407 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293332 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0292745 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.029267 |
| RPL11 | ribosomal protein L11 | 0.0292058 |
| TPR | translocated promoter region, nuclear basket protein | 0.0291677 |
| CEP350 | centrosomal protein 350kDa | 0.0291352 |
| CD109 | CD109 molecule | 0.0289368 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0287669 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0287215 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0287188 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0285878 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0285837 |
| RPL28 | ribosomal protein L28 | 0.0285255 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0285174 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.028498 |
| CCDC88A | coiled-coil domain containing 88A | 0.0284735 |
| WDR43 | WD repeat domain 43 | 0.0281602 |
| TNRC6A | trinucleotide repeat containing 6A | 0.028121 |
| ETV6 | ets variant 6 | 0.0280686 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.028011 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0279921 |
| SFXN1 | sideroflexin 1 | 0.0279562 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0279457 |
| RPL23 | ribosomal protein L23 | 0.0279375 |
| TXNRD1 | thioredoxin reductase 1 | 0.0276227 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0275644 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0272018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.196568 |
| FN1 | fibronectin 1 | -0.183552 |
| NRG1 | neuregulin 1 | -0.114017 |
| ASPH | aspartate beta-hydroxylase | -0.107805 |
| NTN4 | netrin 4 | -0.0913569 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0893683 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0867735 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0854123 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0815378 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.08122 |
| NDRG1 | N-myc downstream regulated 1 | -0.0807416 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0750599 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0734006 |
| PALLD | palladin, cytoskeletal associated protein | -0.0680479 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0656743 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0642491 |
| INTS6 | integrator complex subunit 6 | -0.0631177 |
| SYT1 | synaptotagmin I | -0.0627493 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0612019 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0590496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0580876 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0546615 |
| AEBP2 | AE binding protein 2 | -0.0526886 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0515776 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0497521 |
| RAI14 | retinoic acid induced 14 | -0.049415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0491247 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0489684 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0488995 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0466728 |
| AHNAK | AHNAK nucleoprotein | -0.0462258 |
| RNF213 | ring finger protein 213 | -0.0427605 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0419702 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0409723 |
| SQSTM1 | sequestosome 1 | -0.0401083 |
| RAB31 | RAB31, member RAS oncogene family | -0.0395711 |
| FTL | ferritin, light polypeptide | -0.0395326 |
| HMGA2 | high mobility group AT-hook 2 | -0.0395081 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0394042 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0387219 |
| NRP1 | neuropilin 1 | -0.0384831 |
| WDR1 | WD repeat domain 1 | -0.0377748 |
| NPAS2 | neuronal PAS domain protein 2 | -0.037726 |
| FHL2 | four and a half LIM domains 2 | -0.0377242 |
| RAB10 | RAB10, member RAS oncogene family | -0.0369305 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0369033 |
| RCOR1 | REST corepressor 1 | -0.0366242 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0364565 |
| NXN | nucleoredoxin | -0.0361186 |
| COPA | coatomer protein complex, subunit alpha | -0.0354806 |
| IER3 | immediate early response 3 | -0.0349553 |
| GLIS3 | GLIS family zinc finger 3 | -0.0343996 |
| TGFB1 | transforming growth factor, beta 1 | -0.0343995 |
| RHEB | Ras homolog enriched in brain | -0.0339878 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0338906 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0338743 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0337345 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.033416 |
| EGR1 | early growth response 1 | -0.032822 |
| RYBP | RING1 and YY1 binding protein | -0.0324797 |
| ZNF644 | zinc finger protein 644 | -0.0323497 |
| CCDC138 | coiled-coil domain containing 138 | -0.0322806 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0322648 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.031937 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0319116 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0314823 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0313599 |
| ARF1 | ADP-ribosylation factor 1 | -0.0309023 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.030659 |
| RIGI | RNA sensor RIG-I | -0.0301008 |
| CORO1C | coronin, actin binding protein, 1C | -0.0300575 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0298363 |
| SETX | senataxin | -0.029534 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0294263 |
| LOXL2 | lysyl oxidase-like 2 | -0.029102 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0290876 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0288587 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0287276 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0287016 |
| KSR1 | kinase suppressor of ras 1 | -0.0286234 |
| MYO10 | myosin X | -0.0285643 |
| TNS3 | tensin 3 | -0.0282099 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.028167 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0280175 |
| NBEA | neurobeachin | -0.0278725 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0278395 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0277028 |
| FBXO11 | F-box protein 11 | -0.0276708 |
| SEPTIN9 | septin 9 | -0.027376 |
| MAP1B | microtubule-associated protein 1B | -0.0272276 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0269565 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0266807 |
| LOX | lysyl oxidase | -0.0266777 |
| ABR | active BCR-related | -0.0265064 |
| ACTG1 | actin gamma 1 | -0.026373 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.025919 |
| ACTN1 | actinin, alpha 1 | -0.0258855 |
| FLNA | filamin A, alpha | -0.0258634 |
| S100A10 | S100 calcium binding protein A10 | -0.0258279 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.025824 |
