| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0776806 |
| PTMA | prothymosin, alpha | 0.0640998 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0640042 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0606274 |
| KRT18 | keratin 18, type I | 0.04829 |
| PGK1 | phosphoglycerate kinase 1 | 0.0461478 |
| RPL12 | ribosomal protein L12 | 0.0437631 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0437148 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0401778 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0395873 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0394371 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0378492 |
| RPS3 | ribosomal protein S3 | 0.0366013 |
| CD47 | CD47 molecule | 0.0349404 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0348235 |
| RPL37A | ribosomal protein L37a | 0.033957 |
| KRT19 | keratin 19, type I | 0.0329948 |
| RPS21 | ribosomal protein S21 | 0.0316981 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.03154 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0311406 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0306224 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0305841 |
| RNF149 | ring finger protein 149 | 0.0302624 |
| AFDN | afadin, adherens junction formation factor | 0.0300996 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0300455 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0297966 |
| RPL27A | ribosomal protein L27a | 0.0290432 |
| RPS6 | ribosomal protein S6 | 0.0285247 |
| RPL18 | ribosomal protein L18 | 0.028149 |
| OGA | O-GlcNAcase | 0.0280041 |
| HOXB6 | homeobox B6 | 0.0275467 |
| RPL19 | ribosomal protein L19 | 0.0272515 |
| FRMD5 | FERM domain containing 5 | 0.0270649 |
| RPS17 | ribosomal protein S17 | 0.0270644 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0268217 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0264282 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0262323 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0258978 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0258334 |
| CBX3 | chromobox homolog 3 | 0.0254407 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0253527 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0252485 |
| MSI2 | musashi RNA-binding protein 2 | 0.0249016 |
| MED13L | mediator complex subunit 13-like | 0.02477 |
| RPS8 | ribosomal protein S8 | 0.024299 |
| THOC2 | THO complex 2 | 0.0241493 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0238147 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232174 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0231142 |
| B2M | beta-2-microglobulin | 0.0229134 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0226378 |
| CASC3 | cancer susceptibility candidate 3 | 0.0223729 |
| RBM25 | RNA binding motif protein 25 | 0.022297 |
| RYK | receptor-like tyrosine kinase | 0.022211 |
| RPLP0 | ribosomal protein, large, P0 | 0.0219842 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.0219598 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0218987 |
| RREB1 | ras responsive element binding protein 1 | 0.0218066 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0214955 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0211785 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.021081 |
| FAM3C | family with sequence similarity 3, member C | 0.0207424 |
| USP3 | ubiquitin specific peptidase 3 | 0.0206596 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.020557 |
| FAT1 | FAT atypical cadherin 1 | 0.020414 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0202499 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0202058 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0200817 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0200736 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0199974 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0196997 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0196862 |
| NCKAP1 | NCK-associated protein 1 | 0.019553 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0195184 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193741 |
| TMSB4X | thymosin beta 4, X-linked | 0.0192488 |
| RPS2 | ribosomal protein S2 | 0.0192405 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0192376 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0191019 |
| ZFR | zinc finger RNA binding protein | 0.0189627 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0187642 |
| MKRN1 | makorin ring finger protein 1 | 0.0187027 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0185339 |
| RPLP1 | ribosomal protein, large, P1 | 0.018409 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.0183705 |
| RPL26 | ribosomal protein L26 | 0.0182601 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0180845 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0179365 |
| SEPTIN2 | septin 2 | 0.0179268 |
| ZNF326 | zinc finger protein 326 | 0.0176871 |
| ONECUT3 | one cut homeobox 3 | 0.0172704 |
| CKAP5 | cytoskeleton associated protein 5 | 0.017268 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0170777 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0170494 |
| SP3 | Sp3 transcription factor | 0.0170312 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0167741 |
| FN1 | fibronectin 1 | 0.0167232 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0167118 |
| RPS27 | ribosomal protein S27 | 0.0166285 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0164913 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.24903 |
| TMSB10 | thymosin beta 10 | -0.16058 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151701 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.146633 |
| IFRD1 | interferon-related developmental regulator 1 | -0.105054 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.094933 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.094898 |
| RPS27A | ribosomal protein S27a | -0.0862582 |
| JUN | jun proto-oncogene | -0.0817546 |
| KRT8 | keratin 8, type II | -0.0786773 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0773096 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0750355 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0714035 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0702919 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0702273 |
| EZR | ezrin | -0.0695197 |
| GNAS | GNAS complex locus | -0.0673229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0671308 |
| ACTG1 | actin gamma 1 | -0.0625974 |
| NEBL | nebulette | -0.0583784 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0575763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0571384 |
| PCBP2 | poly(rC) binding protein 2 | -0.0564459 |
| ANXA2 | annexin A2 | -0.0558258 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0542434 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0541714 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0533225 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0519175 |
| EGR1 | early growth response 1 | -0.0517076 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0514141 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0507823 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0504756 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0501832 |
| FTL | ferritin, light polypeptide | -0.0500303 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.049745 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0497099 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0480306 |
| PKM | pyruvate kinase, muscle | -0.0474358 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0472147 |
| FLNA | filamin A, alpha | -0.0469141 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0458104 |
| EMP1 | epithelial membrane protein 1 | -0.045268 |
| GOLGB1 | golgin B1 | -0.0449671 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0447053 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0446189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0444423 |
| FUS | FUS RNA binding protein | -0.0439772 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0438198 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0436627 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0431818 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0428081 |
| MYO1E | myosin IE | -0.0415708 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0415053 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0407889 |
| ACTN4 | actinin, alpha 4 | -0.0402851 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0401274 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0399542 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0398378 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0388172 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0381399 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0380104 |
| OXSR1 | oxidative stress responsive 1 | -0.0374192 |
| YAP1 | Yes-associated protein 1 | -0.0364886 |
| CALU | calumenin | -0.0357146 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.035615 |
| AHNAK | AHNAK nucleoprotein | -0.0355313 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0354155 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0351522 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0351426 |
| CADPS | Ca++-dependent secretion activator | -0.0349845 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0347499 |
| CDK13 | cyclin-dependent kinase 13 | -0.0347419 |
| RBM39 | RNA binding motif protein 39 | -0.0344789 |
| POTEF | POTE ankyrin domain family, member F | -0.0342464 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0341519 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0341411 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0340791 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0337834 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0335317 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0335067 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0330848 |
| VMP1 | vacuole membrane protein 1 | -0.0330794 |
| TXNRD1 | thioredoxin reductase 1 | -0.0330768 |
| USP34 | ubiquitin specific peptidase 34 | -0.0330156 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0327852 |
| RNF213 | ring finger protein 213 | -0.0327512 |
| CCND1 | cyclin D1 | -0.03254 |
| JMJD1C | jumonji domain containing 1C | -0.0319897 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0318528 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0317073 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0313671 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0312649 |
| TXNIP | thioredoxin interacting protein | -0.031193 |
| PLSCR1 | phospholipid scramblase 1 | -0.030587 |
| RHOA | ras homolog family member A | -0.0305805 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0305005 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0299985 |
| GLG1 | golgi glycoprotein 1 | -0.0299215 |
| AMOTL2 | angiomotin like 2 | -0.0296553 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0296398 |
