| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.13584 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.135458 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127082 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.123567 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.118152 |
| VIM | vimentin | 0.0982825 |
| ITGA6 | integrin, alpha 6 | 0.0962557 |
| NAV2 | neuron navigator 2 | 0.0961599 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.094347 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0894479 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0866458 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0842335 |
| RPL23 | ribosomal protein L23 | 0.0786972 |
| RPS3 | ribosomal protein S3 | 0.0754799 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0724992 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0719455 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0717997 |
| ETNK1 | ethanolamine kinase 1 | 0.0708267 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0630192 |
| RACK1 | receptor for activated C kinase 1 | 0.0596674 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0594246 |
| RPL37A | ribosomal protein L37a | 0.0593275 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0589203 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0585893 |
| KRT18 | keratin 18, type I | 0.0573858 |
| KRT8 | keratin 8, type II | 0.0568437 |
| PGK1 | phosphoglycerate kinase 1 | 0.0561728 |
| OGA | O-GlcNAcase | 0.0559244 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0547206 |
| TMEM41B | transmembrane protein 41B | 0.0543499 |
| RPS8 | ribosomal protein S8 | 0.0531853 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0531039 |
| THOC2 | THO complex 2 | 0.0525099 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0520713 |
| ANLN | anillin, actin binding protein | 0.0511982 |
| AFDN | afadin, adherens junction formation factor | 0.0494201 |
| SMC4 | structural maintenance of chromosomes 4 | 0.049356 |
| RPL26 | ribosomal protein L26 | 0.0490768 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.048946 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0480957 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.047622 |
| RUNX1 | runt-related transcription factor 1 | 0.0464123 |
| DIAPH3 | diaphanous-related formin 3 | 0.0462744 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0451158 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0446048 |
| S100A6 | S100 calcium binding protein A6 | 0.0440487 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0420755 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0418132 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0404924 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0388584 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0387697 |
| RPS12 | ribosomal protein S12 | 0.0383549 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0382585 |
| RPS21 | ribosomal protein S21 | 0.0380646 |
| PCBP2 | poly(rC) binding protein 2 | 0.0378595 |
| CDH13 | cadherin 13 | 0.0371608 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0371344 |
| DUSP6 | dual specificity phosphatase 6 | 0.037009 |
| RPL35A | ribosomal protein L35a | 0.0369215 |
| ZNF292 | zinc finger protein 292 | 0.0364326 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0364037 |
| ENO1 | enolase 1, (alpha) | 0.0362441 |
| KRT5 | keratin 5, type II | 0.0359169 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0356225 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0352816 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0351547 |
| VMP1 | vacuole membrane protein 1 | 0.0350342 |
| RPS4X | ribosomal protein S4, X-linked | 0.0348851 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0344633 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0344002 |
| ANKRD10 | ankyrin repeat domain 10 | 0.034059 |
| TPI1 | triosephosphate isomerase 1 | 0.0338156 |
| RAI1 | retinoic acid induced 1 | 0.0334949 |
| RAB6A | RAB6A, member RAS oncogene family | 0.03326 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.032564 |
| ABHD2 | abhydrolase domain containing 2 | 0.0317582 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0315246 |
| RPLP2 | ribosomal protein, large, P2 | 0.0314755 |
| RPS19 | ribosomal protein S19 | 0.0313275 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0308035 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0305881 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0305054 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0302686 |
| TMSB4X | thymosin beta 4, X-linked | 0.0302111 |
| HOXB6 | homeobox B6 | 0.0301518 |
| JAG1 | jagged 1 | 0.0299003 |
| UTRN | utrophin | 0.0298819 |
| RPL12 | ribosomal protein L12 | 0.0298622 |
| RPL18 | ribosomal protein L18 | 0.0295558 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0295203 |
| CTBP2 | C-terminal binding protein 2 | 0.0294175 |
| RPL31 | ribosomal protein L31 | 0.0291154 |
| ATP11A | ATPase, class VI, type 11A | 0.0288441 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0288402 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0286096 |
| MT2A | metallothionein 2A | 0.028598 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285545 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.0282509 |
| CANX | calnexin | 0.0280532 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0278509 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124473 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.108991 |
| SYT1 | synaptotagmin I | -0.0791157 |
| RPS2 | ribosomal protein S2 | -0.0757359 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0665842 |
| DSPP | dentin sialophosphoprotein | -0.064727 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0641052 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0621908 |
| HSPA8 | heat shock 70kDa protein 8 | -0.060634 |
| AXIN2 | axin 2 | -0.0588626 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0583498 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0582987 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0573099 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0565949 |
| EGR1 | early growth response 1 | -0.0559445 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0543604 |
| IPO7 | importin 7 | -0.0542461 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0540449 |
| ACTG1 | actin gamma 1 | -0.0539459 |
| RBM39 | RNA binding motif protein 39 | -0.0516499 |
| H1-4 | H1.4 linker histone, cluster member | -0.0478605 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.047129 |
| WWOX | WW domain containing oxidoreductase | -0.0468157 |
| TNS3 | tensin 3 | -0.0452999 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0437994 |
| YAP1 | Yes-associated protein 1 | -0.041797 |
| CLTC | clathrin, heavy chain (Hc) | -0.041545 |
| CCND1 | cyclin D1 | -0.0410174 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0409053 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0408757 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0406874 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0406631 |
| RAB10 | RAB10, member RAS oncogene family | -0.0406099 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0403913 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0399854 |
| CD44 | CD44 molecule (Indian blood group) | -0.0396376 |
| IGF2 | insulin-like growth factor 2 | -0.0380806 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0375102 |
| RPL38 | ribosomal protein L38 | -0.0374456 |
| RPL21 | ribosomal protein L21 | -0.0364029 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0361477 |
| EMP1 | epithelial membrane protein 1 | -0.0356977 |
| RPL3 | ribosomal protein L3 | -0.0354714 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0348692 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0345701 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0333171 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0333029 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0331558 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.032982 |
| LMO7 | LIM domain 7 | -0.0328834 |
| XPO1 | exportin 1 | -0.0324253 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0322638 |
| PAPOLA | poly(A) polymerase alpha | -0.0317637 |
| MATR3 | matrin 3 | -0.0316103 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0313305 |
| COBL | cordon-bleu WH2 repeat protein | -0.0311814 |
| CBFB | core-binding factor, beta subunit | -0.0310932 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0310845 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0310462 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0307222 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0304795 |
| MCC | mutated in colorectal cancers | -0.0303384 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0301037 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.029961 |
| SETX | senataxin | -0.0298035 |
| GOLGB1 | golgin B1 | -0.0297637 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.029639 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0294375 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0293304 |
| MYO10 | myosin X | -0.0291243 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0289619 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0284703 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0284207 |
| SERINC5 | serine incorporator 5 | -0.0284048 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0282386 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0277777 |
| H1-5 | H1.5 linker histone, cluster member | -0.0276747 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0276634 |
| USP47 | ubiquitin specific peptidase 47 | -0.0276145 |
| CTSB | cathepsin B | -0.0275679 |
| GPATCH8 | G patch domain containing 8 | -0.0273383 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0270514 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0267801 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0267779 |
| UBAP2 | ubiquitin associated protein 2 | -0.0266387 |
| MSN | moesin | -0.0266246 |
| HMGB1 | high mobility group box 1 | -0.0265863 |
| RBP1 | retinol binding protein 1, cellular | -0.0263879 |
| TXNRD1 | thioredoxin reductase 1 | -0.0263759 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | -0.0262327 |
| GPHN | gephyrin | -0.0261715 |
| YBX3 | Y box binding protein 3 | -0.0260771 |
| FNIP1 | folliculin interacting protein 1 | -0.026075 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0255849 |
| ERBIN | erbb2 interacting protein | -0.0254941 |
| PCDH9 | protocadherin 9 | -0.0253657 |
| PDZD8 | PDZ domain containing 8 | -0.0253497 |
| TXNIP | thioredoxin interacting protein | -0.0252354 |
| STK38L | serine/threonine kinase 38 like | -0.024862 |
| FHIT | fragile histidine triad | -0.0247846 |
