| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.107174 |
| ATP13A3 | ATPase type 13A3 | 0.102412 |
| INHBA | inhibin, beta A | 0.101293 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0967323 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.091654 |
| VIM | vimentin | 0.0886166 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0835287 |
| STC1 | stanniocalcin 1 | 0.0810815 |
| ADM | adrenomedullin | 0.0792291 |
| PCBP2 | poly(rC) binding protein 2 | 0.0784459 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0753716 |
| FMNL2 | formin-like 2 | 0.073947 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0728015 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0717352 |
| GOLGA4 | golgin A4 | 0.0704342 |
| SPAG9 | sperm associated antigen 9 | 0.0699371 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0655262 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0599234 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.058731 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0570925 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0560534 |
| AHNAK | AHNAK nucleoprotein | 0.0544414 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0517039 |
| ENO1 | enolase 1, (alpha) | 0.0516993 |
| RNF145 | ring finger protein 145 | 0.0505383 |
| RPS12 | ribosomal protein S12 | 0.0504292 |
| SRP54 | signal recognition particle 54kDa | 0.0495055 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0470377 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0468682 |
| PTMA | prothymosin, alpha | 0.0467198 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0451744 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0451028 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0449407 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0445179 |
| B2M | beta-2-microglobulin | 0.0441825 |
| NUP58 | nucleoporin 58 | 0.0436351 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0435962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0417499 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.040403 |
| SETD5 | SET domain containing 5 | 0.0403865 |
| OGA | O-GlcNAcase | 0.0399437 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0393804 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0393447 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0386413 |
| DST | dystonin | 0.0376678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0365713 |
| MMP12 | matrix metallopeptidase 12 | 0.0358796 |
| HELZ | helicase with zinc finger | 0.0357514 |
| ZNF292 | zinc finger protein 292 | 0.0352747 |
| TPM3 | tropomyosin 3 | 0.0348445 |
| RPS3 | ribosomal protein S3 | 0.0347025 |
| RPS8 | ribosomal protein S8 | 0.0345627 |
| GPHN | gephyrin | 0.0342213 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0341953 |
| NGLY1 | N-glycanase 1 | 0.0339327 |
| NBAS | neuroblastoma amplified sequence | 0.033817 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0336637 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0332552 |
| RPL3 | ribosomal protein L3 | 0.033067 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0330202 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0328909 |
| NKTR | natural killer cell triggering receptor | 0.032734 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0325332 |
| RPL26 | ribosomal protein L26 | 0.0324725 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0322768 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0321715 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0320025 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0314214 |
| ANXA5 | annexin A5 | 0.031027 |
| RPS6 | ribosomal protein S6 | 0.0309626 |
| COPA | coatomer protein complex, subunit alpha | 0.0308068 |
| RASA2 | RAS p21 protein activator 2 | 0.0306688 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0303042 |
| MEIS1 | Meis homeobox 1 | 0.0301592 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0301014 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0300064 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0299325 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0298666 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0296218 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0293201 |
| CALU | calumenin | 0.0291894 |
| SET | SET nuclear proto-oncogene | 0.0291185 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0290756 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0289585 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0288417 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0284097 |
| RAI1 | retinoic acid induced 1 | 0.0279535 |
| YBX1 | Y box binding protein 1 | 0.0278852 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0278645 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0275679 |
| TFG | TRK-fused gene | 0.0274754 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0274683 |
| SEPTIN9 | septin 9 | 0.0274321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0271435 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.027101 |
| FNIP1 | folliculin interacting protein 1 | 0.0270688 |
| CDK19 | cyclin-dependent kinase 19 | 0.0266838 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0265571 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0264149 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0263873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.422111 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.128504 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.113026 |
| FN1 | fibronectin 1 | -0.0977966 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0861825 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0845624 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0834399 |
| TMSB10 | thymosin beta 10 | -0.0814415 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0758679 |
| FTL | ferritin, light polypeptide | -0.0756076 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0692165 |
| EMP1 | epithelial membrane protein 1 | -0.0674955 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.066424 |
| CD44 | CD44 molecule (Indian blood group) | -0.0623506 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0604375 |
| MYO10 | myosin X | -0.0564873 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0560735 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0549236 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0529216 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0493812 |
| ASPH | aspartate beta-hydroxylase | -0.048155 |
| RPL35A | ribosomal protein L35a | -0.0468523 |
| EGR1 | early growth response 1 | -0.0466159 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0463913 |
| EGFR | epidermal growth factor receptor | -0.0448292 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0442017 |
| RPS24 | ribosomal protein S24 | -0.0435044 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0429162 |
| OSMR | oncostatin M receptor | -0.041401 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0407251 |
| ACTG1 | actin gamma 1 | -0.040578 |
| GLIS3 | GLIS family zinc finger 3 | -0.0377641 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0374858 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0371624 |
| RPLP1 | ribosomal protein, large, P1 | -0.0370648 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0367294 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0362303 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0352013 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0349453 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0348518 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0340876 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0337948 |
| RRBP1 | ribosome binding protein 1 | -0.0326876 |
| RPS19 | ribosomal protein S19 | -0.0317531 |
| SEPTIN11 | septin 11 | -0.0317273 |
| FRMD4A | FERM domain containing 4A | -0.0313954 |
| VCL | vinculin | -0.0309411 |
| CCND1 | cyclin D1 | -0.0306848 |
| CAVIN1 | caveolae associated protein 1 | -0.0302909 |
| NAV1 | neuron navigator 1 | -0.0302289 |
| OXR1 | oxidation resistance 1 | -0.0296983 |
| HMGA2 | high mobility group AT-hook 2 | -0.0287557 |
| FOXP1 | forkhead box P1 | -0.0284602 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0283523 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027385 |
| H1-0 | H1.0 linker histone | -0.0273387 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0272676 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0268231 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255409 |
| SSH1 | slingshot protein phosphatase 1 | -0.0252834 |
| TXNIP | thioredoxin interacting protein | -0.025152 |
| RPS20 | ribosomal protein S20 | -0.0250917 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0248266 |
| FBN1 | fibrillin 1 | -0.0246839 |
| IER3 | immediate early response 3 | -0.0246469 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0241528 |
| CD59 | CD59 molecule, complement regulatory protein | -0.024093 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0240434 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0235092 |
| VDAC1 | voltage-dependent anion channel 1 | -0.023387 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0233298 |
| RAI14 | retinoic acid induced 14 | -0.0227369 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.022503 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0224891 |
| COL1A1 | collagen, type I, alpha 1 | -0.0223165 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0218001 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0217769 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.021716 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0214902 |
| CALD1 | caldesmon 1 | -0.0214453 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0212311 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0211783 |
| RPL34 | ribosomal protein L34 | -0.0210695 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0209982 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0208982 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0206964 |
| IGF2 | insulin-like growth factor 2 | -0.0204983 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0204429 |
| RAB31 | RAB31, member RAS oncogene family | -0.0204266 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0202043 |
| NABP1 | nucleic acid binding protein 1 | -0.0198531 |
| RPL38 | ribosomal protein L38 | -0.019685 |
| BICC1 | BicC family RNA binding protein 1 | -0.0196011 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0195813 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0195535 |
| ARF1 | ADP-ribosylation factor 1 | -0.019453 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0193142 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.019268 |
| GPATCH8 | G patch domain containing 8 | -0.0191637 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0186303 |
