Prediabetes Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0362046
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Genes

190 genes associated with the disease Prediabetes Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACTB actin, beta
ADA adenosine deaminase
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
AFM afamin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMBRA1 autophagy/beclin-1 regulator 1
AMY2A amylase, alpha 2A (pancreatic)
ANGPTL3 angiopoietin-like 3
ANGPTL8 angiopoietin like 8
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ATF6 activating transcription factor 6
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP4 bone morphogenetic protein 4
C1QTNF5 C1q and tumor necrosis factor related protein 5
CABIN1 calcineurin binding protein 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CAPNS1 calpain, small subunit 1
CAT catalase
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CD68 CD68 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CETP cholesteryl ester transfer protein, plasma
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP2 cartilage intermediate layer protein 2
CLOCK clock circadian regulator
CP ceruloplasmin (ferroxidase)
CPD carboxypeptidase D
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
DACH1 dachshund family transcription factor 1
DBP D site of albumin promoter (albumin D-box) binding protein
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
DPP4 dipeptidyl-peptidase 4
DSPP dentin sialophosphoprotein
EDN1 endothelin 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM132B family with sequence similarity 132, member B
FANCA Fanconi anemia, complementation group A
FBN1 fibrillin 1
FFAR1 free fatty acid receptor 1
FGF23 fibroblast growth factor 23
FST follistatin
FTO fat mass and obesity associated
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCG glucagon
GCK glucokinase (hexokinase 4)
GDF10 growth differentiation factor 10
GDF15 growth differentiation factor 15
GIP gastric inhibitory polypeptide
GLP1R glucagon-like peptide 1 receptor
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRA major histocompatibility complex, class II, DR alpha
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IAPP islet amyloid polypeptide
IDE insulin-degrading enzyme
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL15 interleukin 15
IL18 interleukin 18
IL22 interleukin 22
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
INS insulin
INTS3 integrator complex subunit 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KIFBP kinesin family binding protein
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LPA lipoprotein, Lp(a)
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP6 microtubule-associated protein 6
MAPK8 mitogen-activated protein kinase 8
MBL2 mannose-binding lectin (protein C) 2, soluble
MET MET proto-oncogene, receptor tyrosine kinase
METRNL meteorin, glial cell differentiation regulator-like
MFN2 mitofusin 2
MGC57346-CRHR1 MGC57346-CRHR1 readthrough
MGP matrix Gla protein
MLXIPL MLX interacting protein-like
MMP8 matrix metallopeptidase 8
MPO myeloperoxidase
MSTN myostatin
MTMR9 myotubularin related protein 9
MTNR1B melatonin receptor 1B
MVD mevalonate (diphospho) decarboxylase
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NOG noggin
NOTCH4 notch 4
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG4 neuregulin 4
OCLN occludin
PADI4 peptidyl arginine deiminase, type IV
PCSK9 proprotein convertase subtilisin/kexin type 9
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGC progastricsin (pepsinogen C)
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
PNPLA8 patatin-like phospholipase domain containing 8
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRL prolactin
PTH parathyroid hormone
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
PTRH2 peptidyl-tRNA hydrolase 2
PYY peptide YY
RBP4 retinol binding protein 4, plasma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RTN4R reticulon 4 receptor
SCGN secretagogin, EF-hand calcium binding protein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP5 secreted frizzled-related protein 5
SHBG sex hormone-binding globulin
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A10 solute carrier family 30, member 10
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNAP47 synaptosomal-associated protein, 47kDa
SNU13 small nuclear ribonucleoprotein 13
SOAT1 sterol O-acyltransferase 1
SOST sclerostin
SPP1 secreted phosphoprotein 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPX spexin hormone
SREBF1 sterol regulatory element binding transcription factor 1
SRGN serglycin
STAP2 signal transducing adaptor family member 2
TBC1D4 TBC1 domain family, member 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
THBS4 thrombospondin 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TPM3 tropomyosin 3
TTN titin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UMOD uromodulin
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XBP1 X-box binding protein 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZGLP1 zinc finger, GATA-like protein 1