Prestwick-1080-3796 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the Prestwick-1080-3796 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAA2 acetyl-CoA acyltransferase 2
ADD2 adducin 2 (beta)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDOB aldolase B, fructose-bisphosphate
APOB apolipoprotein B
ASTN1 astrotactin 1
ATN1 atrophin 1
BTN3A2 butyrophilin, subfamily 3, member A2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCR4 chemokine (C-C motif) receptor 4
CD53 CD53 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLTC clathrin, heavy chain (Hc)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CREBZF CREB/ATF bZIP transcription factor
CTNNA2 catenin (cadherin-associated protein), alpha 2
CYLD cylindromatosis (turban tumor syndrome)
DKFZP434L187 uncharacterized LOC26082
DOPEY1 dopey family member 1
EFR3B EFR3 homolog B (S. cerevisiae)
EML2 echinoderm microtubule associated protein like 2
ENG endoglin
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FLT3LG fms-related tyrosine kinase 3 ligand
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPR85 G protein-coupled receptor 85
GRK4 G protein-coupled receptor kinase 4
GZMK granzyme K (granzyme 3; tryptase II)
HEG1 heart development protein with EGF-like domains 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIC2 hypermethylated in cancer 2
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HR hair growth associated
IFFO1 intermediate filament family orphan 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF21B kinesin family member 21B
KRT19P2 keratin 19 pseudogene 2
KRT24 keratin 24, type I
LAMA4 laminin, alpha 4
LGSN lengsin, lens protein with glutamine synthetase domain
LOC284244 uncharacterized LOC284244
LOXL2 lysyl oxidase-like 2
LPL lipoprotein lipase
LRP4 low density lipoprotein receptor-related protein 4
MAP2K7 mitogen-activated protein kinase kinase 7
MBD2 methyl-CpG binding domain protein 2
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MTSS1 metastasis suppressor 1
MUC3B mucin 3B, cell surface associated
MYL10 myosin, light chain 10, regulatory
MYOZ1 myozenin 1
NEK1 NIMA-related kinase 1
NPHP1 nephronophthisis 1 (juvenile)
NPTX2 neuronal pentraxin II
NUP54 nucleoporin 54kDa
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PCDHB3 protocadherin beta 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PNMAL1 paraneoplastic Ma antigen family-like 1
POU3F2 POU class 3 homeobox 2
POU3F4 POU class 3 homeobox 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTRF polymerase I and transcript release factor
PYHIN1 pyrin and HIN domain family, member 1
RAB6A RAB6A, member RAS oncogene family
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1
RB1 retinoblastoma 1
RGS9 regulator of G-protein signaling 9
RPS4Y1 ribosomal protein S4, Y-linked 1
SCN3B sodium channel, voltage gated, type III beta subunit
SFTPB surfactant protein B
SKIL SKI-like proto-oncogene
STAT2 signal transducer and activator of transcription 2, 113kDa
SULT4A1 sulfotransferase family 4A, member 1
SYMPK symplekin
SYN3 synapsin III
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TBX21 T-box 21
TBX6 T-box 6
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR8 toll-like receptor 8
TP63 tumor protein p63
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TTLL1 tubulin tyrosine ligase-like family member 1
UBA7 ubiquitin-like modifier activating enzyme 7
WFDC1 WAP four-disulfide core domain 1
WNT16 wingless-type MMTV integration site family, member 16
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZMAT4 zinc finger, matrin-type 4
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AKR1C2 aldo-keto reductase family 1, member C2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARL15 ADP-ribosylation factor-like 15
AURKC aurora kinase C
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
C1R complement component 1, r subcomponent
CAMKMT calmodulin-lysine N-methyltransferase
CDADC1 cytidine and dCMP deaminase domain containing 1
CIR1 corepressor interacting with RBPJ, 1
CLSTN3 calsyntenin 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COPZ2 coatomer protein complex, subunit zeta 2
CUZD1 CUB and zona pellucida-like domains 1
CYB5R2 cytochrome b5 reductase 2
CYTH3 cytohesin 3
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNM3 dynamin 3
DPF3 D4, zinc and double PHD fingers, family 3
ELSPBP1 epididymal sperm binding protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPN1 epsin 1
FAM120C family with sequence similarity 120C
FBXO31 F-box protein 31
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRS3 fibroblast growth factor receptor substrate 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR21 G protein-coupled receptor 21
GRB7 growth factor receptor-bound protein 7
GREB1L growth regulation by estrogen in breast cancer-like
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H4A histone cluster 1, H4a
IL12A interleukin 12A
IL22 interleukin 22
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM8 lysine (K)-specific demethylase 8
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
KRT4 keratin 4, type II
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIPG lipase, endothelial
LOC157562 uncharacterized LOC157562
LOC390998 ribosomal protein L10 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
MCOLN3 mucolipin 3
MRPL44 mitochondrial ribosomal protein L44
NDE1 nudE neurodevelopment protein 1
NDNF neuron-derived neurotrophic factor
NEK11 NIMA-related kinase 11
NHEJ1 nonhomologous end-joining factor 1
NKX3-2 NK3 homeobox 2
NOTCH1 notch 1
NPFFR1 neuropeptide FF receptor 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRPH peripherin
PRSS22 protease, serine, 22
PYCARD PYD and CARD domain containing
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPH3A rabphilin 3A
RPH3AL rabphilin 3A-like (without C2 domains)
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SPRYD7 SPRY domain containing 7
TCEAL2 transcription elongation factor A (SII)-like 2
TH tyrosine hydroxylase
THOP1 thimet oligopeptidase 1
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TMEM8B transmembrane protein 8B
TRAC T cell receptor alpha constant
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TTC30A tetratricopeptide repeat domain 30A
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBOX5 U-box domain containing 5
VEZT vezatin, adherens junctions transmembrane protein
VWA1 von Willebrand factor A domain containing 1
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF529 zinc finger protein 529
ZNRD1-AS1 ZNRD1 antisense RNA 1