| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the Prestwick-1080-3878 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK | AHNAK nucleoprotein |
| AK1 | adenylate kinase 1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CAPN10 | calpain 10 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDH18 | cadherin 18, type 2 |
| CLIC2 | chloride intracellular channel 2 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CREBBP | CREB binding protein |
| CRMP1 | collapsin response mediator protein 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CUL2 | cullin 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EGR1 | early growth response 1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EMID1 | EMI domain containing 1 |
| EPN2 | epsin 2 |
| FAM63B | family with sequence similarity 63, member B |
| FBXO2 | F-box protein 2 |
| FCMR | Fc fragment of IgM receptor |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| GON4L | gon-4-like (C. elegans) |
| GPR137 | G protein-coupled receptor 137 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HDAC6 | histone deacetylase 6 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL1B | interleukin 1, beta |
| IL2 | interleukin 2 |
| IL2RB | interleukin 2 receptor, beta |
| ITM2B | integral membrane protein 2B |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0754 | KIAA0754 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LHX1 | LIM homeobox 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAK | male germ cell-associated kinase |
| MAP1A | microtubule-associated protein 1A |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED25 | mediator complex subunit 25 |
| MGC2889 | uncharacterized protein MGC2889 |
| MOB3B | MOB kinase activator 3B |
| MX2 | MX dynamin-like GTPase 2 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NDRG2 | NDRG family member 2 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRF1 | nuclear respiratory factor 1 |
| OLFML2A | olfactomedin-like 2A |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDLIM5 | PDZ and LIM domain 5 |
| PRX | periaxin |
| PTAFR | platelet-activating factor receptor |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB3B | RAB3B, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RPH3A | rabphilin 3A |
| RRBP1 | ribosome binding protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
| SIRT5 | sirtuin 5 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SMYD2 | SET and MYND domain containing 2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMOD1 | tropomodulin 1 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| XAF1 | XIAP associated factor 1 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF235 | zinc finger protein 235 |
| ZNF484 | zinc finger protein 484 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBC3 | BCL2 binding component 3 |
| BCO1 | beta-carotene oxygenase 1 |
| BMP4 | bone morphogenetic protein 4 |
| BST2 | bone marrow stromal cell antigen 2 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR1 | complement component 5a receptor 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC64 | coiled-coil domain containing 64 |
| CCNK | cyclin K |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD1A | CD1a molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD8A | CD8a molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTSF | cathepsin F |
| DLL3 | delta-like 3 (Drosophila) |
| ELL | elongation factor RNA polymerase II |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF13 | fibroblast growth factor 13 |
| FGL1 | fibrinogen-like 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLT4 | fms-related tyrosine kinase 4 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GFI1 | growth factor independent 1 transcription repressor |
| GPR143 | G protein-coupled receptor 143 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIST1H3E | histone cluster 1, H3e |
| HMOX1 | heme oxygenase 1 |
| HSF4 | heat shock transcription factor 4 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| ING4 | inhibitor of growth family, member 4 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITM2C | integral membrane protein 2C |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT15 | keratin 15, type I |
| LOC729164 | hCG1732469 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEFV | Mediterranean fever |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NPPA | natriuretic peptide A |
| NPR3 | natriuretic peptide receptor 3 |
| NPTX1 | neuronal pentraxin I |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSMR | oncostatin M receptor |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLL | polymerase (DNA directed), lambda |
| PORCN | porcupine homolog (Drosophila) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRSS53 | protease, serine, 53 |
| RAB3D | RAB3D, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TFDP3 | transcription factor Dp family, member 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TSPAN9 | tetraspanin 9 |
| UCN | urocortin |
| UNC119 | unc-119 homolog (C. elegans) |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF574 | zinc finger protein 574 |
| ZNF816 | zinc finger protein 816 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
