| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-1080-4354 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ASMT | acetylserotonin O-methyltransferase |
| ASPH | aspartate beta-hydroxylase |
| ATXN7L1 | ataxin 7-like 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BICC1 | BicC family RNA binding protein 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTNL8 | butyrophilin-like 8 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CDC14B | cell division cycle 14B |
| CEP135 | centrosomal protein 135kDa |
| CEP41 | centrosomal protein 41kDa |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLDN14 | claudin 14 |
| COL7A1 | collagen, type VII, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| EFS | embryonal Fyn-associated substrate |
| EGF | epidermal growth factor |
| EN2 | engrailed homeobox 2 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGF16 | fibroblast growth factor 16 |
| FRMD1 | FERM domain containing 1 |
| FRMD8 | FERM domain containing 8 |
| FYB | FYN binding protein |
| GRM6 | glutamate receptor, metabotropic 6 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| IFI44 | interferon-induced protein 44 |
| IFT54 | intraflagellar transport 54 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF8 | interferon regulatory factor 8 |
| JPH3 | junctophilin 3 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLK3 | kallikrein-related peptidase 3 |
| KRT19P2 | keratin 19 pseudogene 2 |
| KRTAP2-4 | keratin associated protein 2-4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK1 | LIM domain kinase 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC75B | leucine rich repeat containing 75B |
| LTC4S | leukotriene C4 synthase |
| LYZL6 | lysozyme-like 6 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MRAS | muscle RAS oncogene homolog |
| MUC3B | mucin 3B, cell surface associated |
| MYRIP | myosin VIIA and Rab interacting protein |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NRG1 | neuregulin 1 |
| OLFM4 | olfactomedin 4 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PML | promyelocytic leukemia |
| PRLH | prolactin releasing hormone |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| RAB3B | RAB3B, member RAS oncogene family |
| RBM17 | RNA binding motif protein 17 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| SCRG1 | stimulator of chondrogenesis 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLA | Src-like-adaptor |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC30A10 | solute carrier family 30, member 10 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TAGLN3 | transgelin 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TM6SF2 | transmembrane 6 superfamily member 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNIK | TRAF2 and NCK interacting kinase |
| TP63 | tumor protein p63 |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIM22 | tripartite motif containing 22 |
| TRIM31 | tripartite motif containing 31 |
| UNC13A | unc-13 homolog A (C. elegans) |
| UTS2 | urotensin 2 |
| VCAN | versican |
| ZNF235 | zinc finger protein 235 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BOLA1 | bolA family member 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CDK20 | cyclin-dependent kinase 20 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHKB | choline kinase beta |
| CLDN1 | claudin 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CORO7 | coronin 7 |
| CRIP2 | cysteine-rich protein 2 |
| CST3 | cystatin C |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTSD | cathepsin D |
| CUEDC1 | CUE domain containing 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EVPL | envoplakin |
| EXO5 | exonuclease 5 |
| FBRS | fibrosin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GPR143 | G protein-coupled receptor 143 |
| GPS1 | G protein pathway suppressor 1 |
| GRAMD1C | GRAM domain containing 1C |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BJ | histone cluster 1, H2bj |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL17RA | interleukin 17 receptor A |
| KIAA0319L | KIAA0319-like |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MALL | mal, T-cell differentiation protein-like |
| METRN | meteorin, glial cell differentiation regulator |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPG | N-methylpurine-DNA glycosylase |
| MVD | mevalonate (diphospho) decarboxylase |
| NBEAL2 | neurobeachin-like 2 |
| NES | nestin |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NXPH4 | neurexophilin 4 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PORCN | porcupine homolog (Drosophila) |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF121 | ring finger protein 121 |
| RNF208 | ring finger protein 208 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAGB | Ras-related GTP binding B |
| SCPEP1 | serine carboxypeptidase 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SKI | SKI proto-oncogene |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPAG4 | sperm associated antigen 4 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| THAP7 | THAP domain containing 7 |
| THBS3 | thrombospondin 3 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM25 | tripartite motif containing 25 |
| TSPO | translocator protein (18kDa) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UROS | uroporphyrinogen III synthase |
| VARS | valyl-tRNA synthetase |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF282 | zinc finger protein 282 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |
