| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-1082-7027 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APP | amyloid beta (A4) precursor protein |
| ARTN | artemin |
| ASPH | aspartate beta-hydroxylase |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BMP2K | BMP2 inducible kinase |
| BMP7 | bone morphogenetic protein 7 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CASD1 | CAS1 domain containing 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCDC121 | coiled-coil domain containing 121 |
| CLEC11A | C-type lectin domain family 11, member A |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTNA | dystrobrevin, alpha |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ETV6 | ets variant 6 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO11 | F-box protein 11 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRK | fyn-related Src family tyrosine kinase |
| FZD7 | frizzled class receptor 7 |
| GLUD2 | glutamate dehydrogenase 2 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL17RA | interleukin 17 receptor A |
| IPO8 | importin 8 |
| IRS2 | insulin receptor substrate 2 |
| JRK | Jrk homolog (mouse) |
| KIAA0125 | KIAA0125 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 |
| LYRM9 | LYR motif containing 9 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MEGF9 | multiple EGF-like-domains 9 |
| MEIS2 | Meis homeobox 2 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MSMB | microseminoprotein, beta- |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDE1 | nudE neurodevelopment protein 1 |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPY5R | neuropeptide Y receptor Y5 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHB13 | protocadherin beta 13 |
| PCM1 | pericentriolar material 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLK4 | polo-like kinase 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| RAB36 | RAB36, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19B | ring finger protein 19B |
| RRBP1 | ribosome binding protein 1 |
| S100A6 | S100 calcium binding protein A6 |
| SASH1 | SAM and SH3 domain containing 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STBD1 | starch binding domain 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLR5 | toll-like receptor 5 |
| TTC23 | tetratricopeptide repeat domain 23 |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF557 | zinc finger protein 557 |
| ZNF79 | zinc finger protein 79 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD14A | abhydrolase domain containing 14A |
| ABHD17B | abhydrolase domain containing 17B |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| BAX | BCL2-associated X protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CAPN5 | calpain 5 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CCDC170 | coiled-coil domain containing 170 |
| CCNO | cyclin O |
| CENPT | centromere protein T |
| CHKB | choline kinase beta |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CUEDC1 | CUE domain containing 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EVPL | envoplakin |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBXO46 | F-box protein 46 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4J | histone cluster 1, H4j |
| HTT | huntingtin |
| IFT140 | intraflagellar transport 140 |
| IFT22 | intraflagellar transport 22 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF9 | interferon regulatory factor 9 |
| KIZ | kizuna centrosomal protein |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTD1 | mbt domain containing 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MXD3 | MAX dimerization protein 3 |
| MYO1F | myosin IF |
| NBEAL2 | neurobeachin-like 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OLFML3 | olfactomedin-like 3 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PCDHA6 | protocadherin alpha 6 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRR14L | proline rich 14-like |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RANGRF | RAN guanine nucleotide release factor |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNFT2 | ring finger protein, transmembrane 2 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SNAI2 | snail family zinc finger 2 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TIGD6 | tigger transposable element derived 6 |
| TMC5 | transmembrane channel-like 5 |
| TMEM104 | transmembrane protein 104 |
| TMEM121 | transmembrane protein 121 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP36 | ubiquitin specific peptidase 36 |
| VEGFC | vascular endothelial growth factor C |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZNF106 | zinc finger protein 106 |
| ZNF266 | zinc finger protein 266 |
