| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-1084-3546 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| B9D2 | B9 protein domain 2 |
| BCO1 | beta-carotene oxygenase 1 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCPG1 | cell cycle progression 1 |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD52 | CD52 molecule |
| CD53 | CD53 molecule |
| CD6 | CD6 molecule |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL1A1 | collagen, type I, alpha 1 |
| CRYAB | crystallin, alpha B |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOK2 | docking protein 2, 56kDa |
| EDNRB | endothelin receptor type B |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPHB2 | EPH receptor B2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FN1 | fibronectin 1 |
| FOXG1 | forkhead box G1 |
| FOXN3 | forkhead box N3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPM6B | glycoprotein M6B |
| GPR15 | G protein-coupled receptor 15 |
| GPR153 | G protein-coupled receptor 153 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA-C | major histocompatibility complex, class I, C |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIFC3 | kinesin family member C3 |
| KLHL35 | kelch-like family member 35 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MC5R | melanocortin 5 receptor |
| MED25 | mediator complex subunit 25 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLANA | melan-A |
| MMP25 | matrix metallopeptidase 25 |
| MRC2 | mannose receptor, C type 2 |
| MSR1 | macrophage scavenger receptor 1 |
| MYLK | myosin light chain kinase |
| MYOF | myoferlin |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPAS2 | neuronal PAS domain protein 2 |
| NPY | neuropeptide Y |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OCA2 | oculocutaneous albinism II |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| PKP1 | plakophilin 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCD1 | phospholipase C, delta 1 |
| PLCH2 | phospholipase C, eta 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PROL1 | proline rich, lacrimal 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RECQL5 | RecQ protein-like 5 |
| RPH3A | rabphilin 3A |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| SAFB | scaffold attachment factor B |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMAD1 | SMAD family member 1 |
| SP100 | SP100 nuclear antigen |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SSTR5 | somatostatin receptor 5 |
| TBX2 | T-box 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM255A | transmembrane protein 255A |
| TTC38 | tetratricopeptide repeat domain 38 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALPK1 | alpha-kinase 1 |
| ANXA6 | annexin A6 |
| APH1B | APH1B gamma secretase subunit |
| ARF5 | ADP-ribosylation factor 5 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP13A2 | ATPase type 13A2 |
| AUP1 | ancient ubiquitous protein 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BOLA1 | bolA family member 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPRIN2 | caprin family member 2 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CBX7 | chromobox homolog 7 |
| CD151 | CD151 molecule (Raph blood group) |
| CDC37 | cell division cycle 37 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN4 | claudin 4 |
| CLIC3 | chloride intracellular channel 3 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYB561D2 | cytochrome b561 family, member D2 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDT | D-dopachrome tautomerase |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DESI1 | desumoylating isopeptidase 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| EMD | emerin |
| ERF | Ets2 repressor factor |
| FAM173A | family with sequence similarity 173, member A |
| FLT4 | fms-related tyrosine kinase 4 |
| FMO4 | flavin containing monooxygenase 4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GAB2 | GRB2-associated binding protein 2 |
| GALE | UDP-galactose-4-epimerase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ISOC2 | isochorismatase domain containing 2 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAGE3 | L antigen family, member 3 |
| METRN | meteorin, glial cell differentiation regulator |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL34 | mitochondrial ribosomal protein L34 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLA2G15 | phospholipase A2, group XV |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PRR7 | proline rich 7 (synaptic) |
| PRSS22 | protease, serine, 22 |
| PRSS8 | protease, serine, 8 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANGAP1 | Ran GTPase activating protein 1 |
| RBM42 | RNA binding motif protein 42 |
| REEP4 | receptor accessory protein 4 |
| RNF121 | ring finger protein 121 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC2A4RG | SLC2A4 regulator |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| SURF2 | surfeit 2 |
| TMEM8A | transmembrane protein 8A |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TWF2 | twinfilin actin binding protein 2 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VAX2 | ventral anterior homeobox 2 |
| WBP2 | WW domain binding protein 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 |
| ZNF593 | zinc finger protein 593 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
