Prestwick-1085-6131 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the Prestwick-1085-6131 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACAN aggrecan
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM17 ADAM metallopeptidase domain 17
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
C21ORF2 chromosome 21 open reading frame 2
CA5B carbonic anhydrase VB, mitochondrial
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CCL22 chemokine (C-C motif) ligand 22
CCND1 cyclin D1
CD1A CD1a molecule
CD80 CD80 molecule
CEP250 centrosomal protein 250kDa
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL1A2 collagen, type I, alpha 2
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK6 dedicator of cytokinesis 6
DUSP7 dual specificity phosphatase 7
EFNA3 ephrin-A3
EFNA5 ephrin-A5
EMILIN2 elastin microfibril interfacer 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ESR1 estrogen receptor 1
FAM120C family with sequence similarity 120C
FOXG1 forkhead box G1
FOXO1 forkhead box O1
GLRA1 glycine receptor, alpha 1
GLT8D2 glycosyltransferase 8 domain containing 2
GPR137 G protein-coupled receptor 137
GRM1 glutamate receptor, metabotropic 1
GTPBP1 GTP binding protein 1
HES1 hes family bHLH transcription factor 1
HIST1H2AI histone cluster 1, H2ai
HLF hepatic leukemia factor
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HUS1 HUS1 checkpoint homolog (S. pombe)
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IQSEC1 IQ motif and Sec7 domain 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNIP1 Kv channel interacting protein 1
KLHL36 kelch-like family member 36
KRT13 keratin 13, type I
MINK1 misshapen-like kinase 1
MIP major intrinsic protein of lens fiber
MKRN3 makorin ring finger protein 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NKTR natural killer cell triggering receptor
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PADI1 peptidyl arginine deiminase, type I
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
POU5F1B POU class 5 homeobox 1B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB1 proline-rich protein BstNI subfamily 1
PRLR prolactin receptor
PSEN2 presenilin 2
RBPMS RNA binding protein with multiple splicing
RFC1 replication factor C (activator 1) 1, 145kDa
SHOX2 short stature homeobox 2
SLAMF7 SLAM family member 7
SNN stannin
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPHK2 sphingosine kinase 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STON1 stonin 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNJ2 synaptojanin 2
TF transferrin
THTPA thiamine triphosphatase
TMCC1 transmembrane and coiled-coil domain family 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPMT thiopurine S-methyltransferase
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TUBG2 tubulin, gamma 2
TYRO3 TYRO3 protein tyrosine kinase
WDR55 WD repeat domain 55
YLPM1 YLP motif containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZMYND11 zinc finger, MYND-type containing 11
ZNF286A zinc finger protein 286A
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
AQP9 aquaporin 9
ASGR2 asialoglycoprotein receptor 2
BHLHE41 basic helix-loop-helix family, member e41
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
C9ORF9 chromosome 9 open reading frame 9
CDHR2 cadherin-related family member 2
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLEC2D C-type lectin domain family 2, member D
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPVL carboxypeptidase, vitellogenic-like
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRMP1 collapsin response mediator protein 1
CRYL1 crystallin, lambda 1
CTSV cathepsin V
DCAF17 DDB1 and CUL4 associated factor 17
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHB4 EPH receptor B4
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FMO4 flavin containing monooxygenase 4
GAA glucosidase, alpha; acid
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJA8 gap junction protein, alpha 8, 50kDa
GK3P glycerol kinase 3 pseudogene
GP6 glycoprotein VI (platelet)
GSPT2 G1 to S phase transition 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HIST1H3G histone cluster 1, H3g
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA14 interferon, alpha 14
IGLV1-44 immunoglobulin lambda variable 1-44
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INA internexin neuronal intermediate filament protein, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA1024 KIAA1024
KIF17 kinesin family member 17
LGALS4 lectin, galactoside-binding, soluble, 4
LIN7B lin-7 homolog B (C. elegans)
LOC730101 uncharacterized LOC730101
LOXL3 lysyl oxidase-like 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MNX1 motor neuron and pancreas homeobox 1
MRPL44 mitochondrial ribosomal protein L44
NKX3-2 NK3 homeobox 2
OMG oligodendrocyte myelin glycoprotein
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE12 phosphodiesterase 12
PGBD5 piggyBac transposable element derived 5
PIPOX pipecolic acid oxidase
PLCD1 phospholipase C, delta 1
PNOC prepronociceptin
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRF1 perforin 1 (pore forming protein)
PRKCZ protein kinase C, zeta
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAP1GAP2 RAP1 GTPase activating protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIN1 Ras and Rab interactor 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCTN1 tectonic family member 1
TMEM246 transmembrane protein 246
TRABD TraB domain containing
TTC4 tetratricopeptide repeat domain 4
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR4 WD repeat domain 4
ZIC3 Zic family member 3
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF137P zinc finger protein 137, pseudogene
ZNF345 zinc finger protein 345
ZNF354A zinc finger protein 354A
ZNF428 zinc finger protein 428
ZNF574 zinc finger protein 574