Prestwick-1085-6250 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the Prestwick-1085-6250 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ALOXE3 arachidonate lipoxygenase 3
AMPD3 adenosine monophosphate deaminase 3
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGAP44 Rho GTPase activating protein 44
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATRNL1 attractin-like 1
BAIAP2 BAI1-associated protein 2
BCAP29 B-cell receptor-associated protein 29
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C14ORF93 chromosome 14 open reading frame 93
C8ORF60 chromosome 8 open reading frame 60
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC57 coiled-coil domain containing 57
CDRT1 CMT1A duplicated region transcript 1
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
CRABP1 cellular retinoic acid binding protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTH cystathionine gamma-lyase
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHD2 EH-domain containing 2
FBXO11 F-box protein 11
FHL1 four and a half LIM domains 1
FNTB farnesyltransferase, CAAX box, beta
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GNAS GNAS complex locus
GOSR2 golgi SNAP receptor complex member 2
GSTCD glutathione S-transferase, C-terminal domain containing
HCFC1 host cell factor C1
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC11 histone deacetylase 11
HFE hemochromatosis
HYI hydroxypyruvate isomerase (putative)
IGLJ3 immunoglobulin lambda joining 3
INCENP inner centromere protein antigens 135/155kDa
IRF1 interferon regulatory factor 1
KCTD7 potassium channel tetramerization domain containing 7
KLF6 Kruppel-like factor 6
LAMA4 laminin, alpha 4
LPIN2 lipin 2
MAP4 microtubule-associated protein 4
MFGE8 milk fat globule-EGF factor 8 protein
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRPL41 mitochondrial ribosomal protein L41
MTCP1 mature T-cell proliferation 1
MXD3 MAX dimerization protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOZ1 myozenin 1
NAAA N-acylethanolamine acid amidase
NDE1 nudE neurodevelopment protein 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
OGFR opioid growth factor receptor
OSBPL10 oxysterol binding protein-like 10
PCGF2 polycomb group ring finger 2
PCOLCE procollagen C-endopeptidase enhancer
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PON3 paraoxonase 3
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRKCQ protein kinase C, theta
PTMS parathymosin
PTRF polymerase I and transcript release factor
RAB36 RAB36, member RAS oncogene family
RBM19 RNA binding motif protein 19
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RUNDC3B RUN domain containing 3B
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH3BP2 SH3-domain binding protein 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX2 SRY (sex determining region Y)-box 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF2 sterol regulatory element binding transcription factor 2
SRSF7 serine/arginine-rich splicing factor 7
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAS2R1 taste receptor, type 2, member 1
TUBA3C tubulin, alpha 3c
UNC13A unc-13 homolog A (C. elegans)
UTRN utrophin
VPRBP Vpr (HIV-1) binding protein
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZKSCAN5 zinc finger with KRAB and SCAN domains 5

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
AHCTF1 AT hook containing transcription factor 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ATAD3A ATPase family, AAA domain containing 3A
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C11ORF80 chromosome 11 open reading frame 80
CDR2L cerebellar degeneration-related protein 2-like
CDT1 chromatin licensing and DNA replication factor 1
CENPJ centromere protein J
CEP192 centrosomal protein 192kDa
CFD complement factor D (adipsin)
CHUK conserved helix-loop-helix ubiquitous kinase
COL9A2 collagen, type IX, alpha 2
CTNNBIP1 catenin, beta interacting protein 1
CTSK cathepsin K
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DMTF1 cyclin D binding myb-like transcription factor 1
DNM1 dynamin 1
DSE dermatan sulfate epimerase
ECHDC3 enoyl CoA hydratase domain containing 3
EFHD2 EF-hand domain family, member D2
EGLN3 egl-9 family hypoxia-inducible factor 3
EPPK1 epiplakin 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
FGGY FGGY carbohydrate kinase domain containing
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BC histone cluster 1, H2bc
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL15RA interleukin 15 receptor, alpha
IL17RB interleukin 17 receptor B
INSIG2 insulin induced gene 2
IRF7 interferon regulatory factor 7
KAT2A K(lysine) acetyltransferase 2A
LAMB3 laminin, beta 3
LGMN legumain
LINC00339 long intergenic non-protein coding RNA 339
LOC100272216 uncharacterized LOC100272216
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MTCL1 microtubule crosslinking factor 1
MTMR11 myotubularin related protein 11
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NAV2 neuron navigator 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NHLRC2 NHL repeat containing 2
NOL6 nucleolar protein 6 (RNA-associated)
NPIPB15 nuclear pore complex interacting protein family, member B15
NRGN neurogranin (protein kinase C substrate, RC3)
PCSK7 proprotein convertase subtilisin/kexin type 7
PECR peroxisomal trans-2-enoyl-CoA reductase
PGM1 phosphoglucomutase 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPCS phosphopantothenoylcysteine synthetase
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTTG3P pituitary tumor-transforming 3, pseudogene
PYGL phosphorylase, glycogen, liver
RNF216 ring finger protein 216
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROGDI rogdi homolog (Drosophila)
RPAP2 RNA polymerase II associated protein 2
RPS17P5 ribosomal protein S17 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SH2D4A SH2 domain containing 4A
SLC46A3 solute carrier family 46, member 3
SNX16 sorting nexin 16
SPATA2L spermatogenesis associated 2-like
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TDRD1 tudor domain containing 1
TFF3 trefoil factor 3 (intestinal)
TM7SF3 transmembrane 7 superfamily member 3
TPST2 tyrosylprotein sulfotransferase 2
TPTE transmembrane phosphatase with tensin homology
TTC17 tetratricopeptide repeat domain 17
ULBP2 UL16 binding protein 2
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
WDR6 WD repeat domain 6
WLS wntless Wnt ligand secretion mediator
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZDHHC24 zinc finger, DHHC-type containing 24
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMAT3 zinc finger, matrin-type 3
ZNF160 zinc finger protein 160
ZNF280D zinc finger protein 280D
ZNF557 zinc finger protein 557
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787