Prestwick-1100-3798 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

193 genes differentially expressed following the Prestwick-1100-3798 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADRA1A adrenoceptor alpha 1A
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
ARHGAP33 Rho GTPase activating protein 33
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATF7 activating transcription factor 7
BCAM basal cell adhesion molecule (Lutheran blood group)
BMP2 bone morphogenetic protein 2
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF12 chromosome 10 open reading frame 12
C5AR2 complement component 5a receptor 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC121 coiled-coil domain containing 121
CCDC134 coiled-coil domain containing 134
CD52 CD52 molecule
CNTFR ciliary neurotrophic factor receptor
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A6 collagen, type IV, alpha 6
COLEC10 collectin sub-family member 10 (C-type lectin)
DIO2 deiodinase, iodothyronine, type II
DMPK dystrophia myotonica-protein kinase
DTNB dystrobrevin, beta
DTX3 deltex 3, E3 ubiquitin ligase
EFR3B EFR3 homolog B (S. cerevisiae)
EXO5 exonuclease 5
EXPH5 exophilin 5
FLJ11292
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FZD10 frizzled class receptor 10
GAS1 growth arrest-specific 1
GDF9 growth differentiation factor 9
GIF gastric intrinsic factor (vitamin B synthesis)
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HNF4A hepatocyte nuclear factor 4, alpha
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
IL5RA interleukin 5 receptor, alpha
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA1024 KIAA1024
KLF12 Kruppel-like factor 12
KLK8 kallikrein-related peptidase 8
LAMB4 laminin, beta 4
LGALS9 lectin, galactoside-binding, soluble, 9
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRRN3 leucine rich repeat neuronal 3
MAN1A2 mannosidase, alpha, class 1A, member 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOBP myelin-associated oligodendrocyte basic protein
MUC3B mucin 3B, cell surface associated
MYRIP myosin VIIA and Rab interacting protein
NAAA N-acylethanolamine acid amidase
NOD2 nucleotide-binding oligomerization domain containing 2
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP88 nucleoporin 88kDa
OBSL1 obscurin-like 1
PASK PAS domain containing serine/threonine kinase
PLVAP plasmalemma vesicle associated protein
POM121L2 POM121 transmembrane nucleoporin-like 2
POU2F2 POU class 2 homeobox 2
PRKG2 protein kinase, cGMP-dependent, type II
PRUNE2 prune homolog 2 (Drosophila)
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTMS parathymosin
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIN3 Ras and Rab interactor 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL10 ribosomal protein L10
RS1 retinoschisin 1
RUNX1 runt-related transcription factor 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SSTR5 somatostatin receptor 5
SYNDIG1 synapse differentiation inducing 1
TAAR5 trace amine associated receptor 5
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D30 TBC1 domain family, member 30
TBX2 T-box 2
TGFB1 transforming growth factor, beta 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TPP1 tripeptidyl peptidase I
UNC13A unc-13 homolog A (C. elegans)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)

decreased expression

Symbol Name
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AKAP5 A kinase (PRKA) anchor protein 5
ALPK3 alpha-kinase 3
ANKH ANKH inorganic pyrophosphate transport regulator
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARPIN actin-related protein 2/3 complex inhibitor
ART1 ADP-ribosyltransferase 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BMP15 bone morphogenetic protein 15
C17ORF70 chromosome 17 open reading frame 70
C3 complement component 3
CAMKMT calmodulin-lysine N-methyltransferase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNJL cyclin J-like
CCNK cyclin K
CEMIP cell migration inducing protein, hyaluronan binding
CEP295 centrosomal protein 295kDa
CES3 carboxylesterase 3
CHRM3 cholinergic receptor, muscarinic 3
CLDN8 claudin 8
COPZ2 coatomer protein complex, subunit zeta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGKE diacylglycerol kinase, epsilon 64kDa
DPF3 D4, zinc and double PHD fingers, family 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGFL7 EGF-like-domain, multiple 7
ELAC1 elaC ribonuclease Z 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMOD fibromodulin
FRS3 fibroblast growth factor receptor substrate 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRB7 growth factor receptor-bound protein 7
HIST1H2AK histone cluster 1, H2ak
HIST1H2BM histone cluster 1, H2bm
IL11RA interleukin 11 receptor, alpha
INO80D INO80 complex subunit D
IPO8 importin 8
IQCG IQ motif containing G
IREB2 iron-responsive element binding protein 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
LRRK1 leucine-rich repeat kinase 1
LYRM9 LYR motif containing 9
MAGEA12 melanoma antigen family A12
MANBA mannosidase, beta A, lysosomal
MARK1 MAP/microtubule affinity-regulating kinase 1
MEFV Mediterranean fever
MTA2 metastasis associated 1 family, member 2
MYL5 myosin, light chain 5, regulatory
MYO19 myosin XIX
NCALD neurocalcin delta
NEK11 NIMA-related kinase 11
NPFFR1 neuropeptide FF receptor 1
NTNG1 netrin G1
P3H1 prolyl 3-hydroxylase 1
PARD6A par-6 family cell polarity regulator alpha
PARP3 poly (ADP-ribose) polymerase family, member 3
PENK proenkephalin
PIP prolactin-induced protein
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PTBP3 polypyrimidine tract binding protein 3
RBMS3 RNA binding motif, single stranded interacting protein 3
RFPL3 ret finger protein-like 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
SCAMP5 secretory carrier membrane protein 5
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLAMF7 SLAM family member 7
SLC12A9 solute carrier family 12, member 9
SLC16A6 solute carrier family 16, member 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SP1 Sp1 transcription factor
STRN striatin, calmodulin binding protein
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TENM4 teneurin transmembrane protein 4
TET3 tet methylcytosine dioxygenase 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
XDH xanthine dehydrogenase
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF219 zinc finger protein 219
ZNF41 zinc finger protein 41
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76