| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the Prestwick-1103-3540 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACTL8 | actin-like 8 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARG1 | arginase 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BMP6 | bone morphogenetic protein 6 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CD82 | CD82 molecule |
| CDC25C | cell division cycle 25C |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DEPDC5 | DEP domain containing 5 |
| DGKI | diacylglycerol kinase, iota |
| DPP4 | dipeptidyl-peptidase 4 |
| DST | dystonin |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EXPH5 | exophilin 5 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FADS2 | fatty acid desaturase 2 |
| FAM184A | family with sequence similarity 184, member A |
| FCAR | Fc fragment of IgA receptor |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GK3P | glycerol kinase 3 pseudogene |
| GLP1R | glucagon-like peptide 1 receptor |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR137 | G protein-coupled receptor 137 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GRM8 | glutamate receptor, metabotropic 8 |
| HDAC6 | histone deacetylase 6 |
| HMOX1 | heme oxygenase 1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| ICOS | inducible T-cell co-stimulator |
| IFT27 | intraflagellar transport 27 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL1B | interleukin 1, beta |
| ING2 | inhibitor of growth family, member 2 |
| INHBA | inhibin, beta A |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KRT6B | keratin 6B, type II |
| LEPR | leptin receptor |
| LIG3 | ligase III, DNA, ATP-dependent |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MNMIP1 | manchette microtubule inner protein 1 |
| MST1 | macrophage stimulating 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NDRG2 | NDRG family member 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPR1 | natriuretic peptide receptor 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OCA2 | oculocutaneous albinism II |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDPN | podoplanin |
| PENK | proenkephalin |
| PLK3 | polo-like kinase 3 |
| PLXNC1 | plexin C1 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PROL1 | proline rich, lacrimal 1 |
| PRTN3 | proteinase 3 |
| PTRF | polymerase I and transcript release factor |
| R3HDM1 | R3H domain containing 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RIN1 | Ras and Rab interactor 1 |
| RND1 | Rho family GTPase 1 |
| RPL10 | ribosomal protein L10 |
| RPS3A | ribosomal protein S3A |
| S100A11 | S100 calcium binding protein A11 |
| SETD1A | SET domain containing 1A |
| SH3BP2 | SH3-domain binding protein 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRPA | signal-regulatory protein alpha |
| SIRT5 | sirtuin 5 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| STK11 | serine/threonine kinase 11 |
| STK17B | serine/threonine kinase 17b |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIM14 | tripartite motif containing 14 |
| TSHR | thyroid stimulating hormone receptor |
| TUBBP5 | tubulin, beta pseudogene 5 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF286A | zinc finger protein 286A |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADM | adrenomedullin |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ANKRD10 | ankyrin repeat domain 10 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBX8 | chromobox homolog 8 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CENPT | centromere protein T |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EN2 | engrailed homeobox 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM188A | family with sequence similarity 188, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO46 | F-box protein 46 |
| FRK | fyn-related Src family tyrosine kinase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H2AK | histone cluster 1, H2ak |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXC4 | homeobox C4 |
| KIF13A | kinesin family member 13A |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MEFV | Mediterranean fever |
| MFAP2 | microfibrillar-associated protein 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| NCALD | neurocalcin delta |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PDE8B | phosphodiesterase 8B |
| PVRL3 | poliovirus receptor-related 3 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF43 | ring finger protein 43 |
| RRAGB | Ras-related GTP binding B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCRN3 | secernin 3 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMIM14 | small integral membrane protein 14 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP1 | Sp1 transcription factor |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| TMEM180 | transmembrane protein 180 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TUBB7P | tubulin, beta 7, pseudogene |
| USP19 | ubiquitin specific peptidase 19 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR91 | WD repeat domain 91 |
| ZNF16 | zinc finger protein 16 |
| ZNF254 | zinc finger protein 254 |
| ZNF33B | zinc finger protein 33B |
| ZNF639 | zinc finger protein 639 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
