Prestwick-1103-6019 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the Prestwick-1103-6019 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACHE acetylcholinesterase (Yt blood group)
AIRE autoimmune regulator
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
APOM apolipoprotein M
ARSD arylsulfatase D
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BEGAIN brain-enriched guanylate kinase-associated
BIRC7 baculoviral IAP repeat containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCRL2 chemokine (C-C motif) receptor-like 2
CD4 CD4 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CELA3A chymotrypsin-like elastase family, member 3A
CELP carboxyl ester lipase pseudogene
CEP135 centrosomal protein 135kDa
CEP164 centrosomal protein 164kDa
CFAP69 cilia and flagella associated protein 69
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPNE7 copine VII
CYLD cylindromatosis (turban tumor syndrome)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCLK2 doublecortin-like kinase 2
DLX4 distal-less homeobox 4
DOK4 docking protein 4
EDDM3A epididymal protein 3A
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ESR1 estrogen receptor 1
FAIM2 Fas apoptotic inhibitory molecule 2
FGF4 fibroblast growth factor 4
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
GAS2L1 growth arrest-specific 2 like 1
GP6 glycoprotein VI (platelet)
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
GPR35 G protein-coupled receptor 35
GSPT1 G1 to S phase transition 1
HIST1H3F histone cluster 1, H3f
HNF1B HNF1 homeobox B
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFNA16 interferon, alpha 16
IGHA1 immunoglobulin heavy constant alpha 1
IL1R2 interleukin 1 receptor, type II
INE1 inactivation escape 1 (non-protein coding)
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0125 KIAA0125
KRT75 keratin 75, type II
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LINC00472 long intergenic non-protein coding RNA 472
LRMP lymphoid-restricted membrane protein
LTBP4 latent transforming growth factor beta binding protein 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MID1 midline 1
MOBP myelin-associated oligodendrocyte basic protein
MRPS18C mitochondrial ribosomal protein S18C
NCR2 natural cytotoxicity triggering receptor 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOVA2 neuro-oncological ventral antigen 2
NPTX2 neuronal pentraxin II
NR2E3 nuclear receptor subfamily 2, group E, member 3
NYX nyctalopin
PCDHGA9 protocadherin gamma subfamily A, 9
PCSK6 proprotein convertase subtilisin/kexin type 6
POM121L2 POM121 transmembrane nucleoporin-like 2
RAB3A RAB3A, member RAS oncogene family
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
S100A9 S100 calcium binding protein A9
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC6A16 solute carrier family 6, member 16
SPI1 Spi-1 proto-oncogene
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STOM stomatin
SYBU syntabulin (syntaxin-interacting)
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TGFA transforming growth factor, alpha
THSD4 thrombospondin, type I, domain containing 4
TLE2 transducin-like enhancer of split 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TRAK1 trafficking protein, kinesin binding 1
TRIM49 tripartite motif containing 49
TSC22D2 TSC22 domain family, member 2
UBE3A ubiquitin protein ligase E3A
UNC5B unc-5 homolog B (C. elegans)
VAV2 vav 2 guanine nucleotide exchange factor
WDR78 WD repeat domain 78
YY2 YY2 transcription factor

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
BRPF1 bromodomain and PHD finger containing, 1
C11ORF63 chromosome 11 open reading frame 63
C22ORF29 chromosome 22 open reading frame 29
CARTPT CART prepropeptide
CCP110 centriolar coiled coil protein 110kDa
CDADC1 cytidine and dCMP deaminase domain containing 1
CDON cell adhesion associated, oncogene regulated
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNGB3 cyclic nucleotide gated channel beta 3
CRIP1 cysteine-rich protein 1 (intestinal)
DACH1 dachshund family transcription factor 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
DRD1 dopamine receptor D1
DSPP dentin sialophosphoprotein
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM155B family with sequence similarity 155, member B
FAM46C family with sequence similarity 46, member C
FRK fyn-related Src family tyrosine kinase
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXD11 homeobox D11
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
IRF9 interferon regulatory factor 9
ITPKB inositol-trisphosphate 3-kinase B
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
KIAA1456 KIAA1456
LPAR3 lysophosphatidic acid receptor 3
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
NBEAL2 neurobeachin-like 2
NPFFR1 neuropeptide FF receptor 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PELI1 pellino E3 ubiquitin protein ligase 1
PILRB paired immunoglobin-like type 2 receptor beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRE protein tyrosine phosphatase, receptor type, E
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP1 RNA polymerase II associated protein 1
SH2D4A SH2 domain containing 4A
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SND1-IT1 SND1 intronic transcript 1
SPRY2 sprouty homolog 2 (Drosophila)
SREK1IP1 SREK1-interacting protein 1
SSBP3 single stranded DNA binding protein 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TAGLN3 transgelin 3
TBX19 T-box 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRABD TraB domain containing
TSPAN5 tetraspanin 5
TTBK2 tau tubulin kinase 2
UPK2 uroplakin 2
VAV1 vav 1 guanine nucleotide exchange factor
XK X-linked Kx blood group
ZNF136 zinc finger protein 136
ZNF329 zinc finger protein 329
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668
ZNF701 zinc finger protein 701