| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the Prestwick-1103-7317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATF6B | activating transcription factor 6 beta |
| ATP9A | ATPase, class II, type 9A |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| COL1A1 | collagen, type I, alpha 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| DRP2 | dystrophin related protein 2 |
| FAM174B | family with sequence similarity 174, member B |
| FAS | Fas cell surface death receptor |
| FLJ11292 | |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPSM3 | G-protein signaling modulator 3 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTF2I | general transcription factor IIi |
| HAMP | hepcidin antimicrobial peptide |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HOXD10 | homeobox D10 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INADL | InaD-like (Drosophila) |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITGB5 | integrin, beta 5 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLF12 | Kruppel-like factor 12 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KYNU | kynureninase |
| LDB1 | LIM domain binding 1 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LMO7 | LIM domain 7 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC399491 | |
| MAP7 | microtubule-associated protein 7 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARS | methionyl-tRNA synthetase |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MED25 | mediator complex subunit 25 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYO1F | myosin IF |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NINJ1 | ninjurin 1 |
| NMT2 | N-myristoyltransferase 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OSBP2 | oxysterol binding protein 2 |
| PEX5 | peroxisomal biogenesis factor 5 |
| PEX7 | peroxisomal biogenesis factor 7 |
| PHF3 | PHD finger protein 3 |
| PKP3 | plakophilin 3 |
| PRF1 | perforin 1 (pore forming protein) |
| PRSS8 | protease, serine, 8 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RANBP1 | RAN binding protein 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RARG | retinoic acid receptor, gamma |
| RGS10 | regulator of G-protein signaling 10 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL7 | ribosomal protein L7 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIX3 | SIX homeobox 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SP100 | SP100 nuclear antigen |
| SRRT | serrate, RNA effector molecule |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TK2 | thymidine kinase 2, mitochondrial |
| TPM2 | tropomyosin 2 (beta) |
| TRIM3 | tripartite motif containing 3 |
| TUSC3 | tumor suppressor candidate 3 |
| WDR18 | WD repeat domain 18 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF253 | zinc finger protein 253 |
| ZNF280D | zinc finger protein 280D |
| ZNF85 | zinc finger protein 85 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BEX1 | brain expressed, X-linked 1 |
| BOLA1 | bolA family member 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNJL | cyclin J-like |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDON | cell adhesion associated, oncogene regulated |
| CEP72 | centrosomal protein 72kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN14 | claudin 14 |
| CORO1A | coronin, actin binding protein, 1A |
| CORT | cortistatin |
| CST4 | cystatin S |
| CTSF | cathepsin F |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAL4 | dynein, axonemal, light chain 4 |
| EAF2 | ELL associated factor 2 |
| EDAR | ectodysplasin A receptor |
| EPN3 | epsin 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FHOD1 | formin homology 2 domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR3 | G protein-coupled receptor 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| H1F0 | H1 histone family, member 0 |
| HIRA | histone cell cycle regulator |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HSPB8 | heat shock 22kDa protein 8 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| IL15RA | interleukin 15 receptor, alpha |
| IQCG | IQ motif containing G |
| JAK2 | Janus kinase 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIFC3 | kinesin family member C3 |
| KPTN | kaptin (actin binding protein) |
| LPAR2 | lysophosphatidic acid receptor 2 |
| MAGEF1 | melanoma antigen family F1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MYH15 | myosin, heavy chain 15 |
| NARFL | nuclear prelamin A recognition factor-like |
| NCS1 | neuronal calcium sensor 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRR14L | proline rich 14-like |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERTAD3 | SERTA domain containing 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAR | steroidogenic acute regulatory protein |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAGLN | transgelin |
| TENM1 | teneurin transmembrane protein 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM183A | transmembrane protein 183A |
| TMEM242 | transmembrane protein 242 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR37 | WD repeat domain 37 |
| XPA | xeroderma pigmentosum, complementation group A |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF197 | zinc finger protein 197 |
| ZNF552 | zinc finger protein 552 |
