| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the Prestwick-642-2815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ACTL8 | actin-like 8 |
| ALS2CL | ALS2 C-terminal like |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARTN | artemin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP11A | ATPase, class VI, type 11A |
| CABIN1 | calcineurin binding protein 1 |
| CACTIN | cactin, spliceosome C complex subunit |
| CAPN15 | calpain 15 |
| CD1E | CD1e molecule |
| CDC42 | cell division cycle 42 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHD9 | chromodomain helicase DNA binding protein 9 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN11 | claudin 11 |
| CORO7 | coronin 7 |
| CPNE7 | copine VII |
| CRMP1 | collapsin response mediator protein 1 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOK4 | docking protein 4 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EPHB2 | EPH receptor B2 |
| ESR1 | estrogen receptor 1 |
| ETV6 | ets variant 6 |
| FAM46C | family with sequence similarity 46, member C |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GMPR | guanosine monophosphate reductase |
| HEG1 | heart development protein with EGF-like domains 1 |
| HSF1 | heat shock transcription factor 1 |
| IL2RG | interleukin 2 receptor, gamma |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KLHL25 | kelch-like family member 25 |
| KRT15 | keratin 15, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP4 | microtubule-associated protein 4 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP11 | matrix metallopeptidase 11 |
| MMP25 | matrix metallopeptidase 25 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NAGLU | N-acetylglucosaminidase, alpha |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| ODAM | odontogenic, ameloblast asssociated |
| ONECUT2 | one cut homeobox 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHB3 | protocadherin beta 3 |
| PDLIM4 | PDZ and LIM domain 4 |
| PIGR | polymeric immunoglobulin receptor |
| PLCD1 | phospholipase C, delta 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRDX2 | peroxiredoxin 2 |
| PRR5 | proline rich 5 (renal) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTN | pleiotrophin |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RNF19B | ring finger protein 19B |
| S100A9 | S100 calcium binding protein A9 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIRT3 | sirtuin 3 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| ST5 | suppression of tumorigenicity 5 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAOK2 | TAO kinase 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM63A | transmembrane protein 63A |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIM21 | tripartite motif containing 21 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBXN6 | UBX domain protein 6 |
| USP32 | ubiquitin specific peptidase 32 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WDR62 | WD repeat domain 62 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF3 | zinc finger protein 3 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC4 | armadillo repeat containing 4 |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEP97 | centrosomal protein 97kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDN15 | claudin 15 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTN1 | contactin 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXO5 | exonuclease 5 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FMOD | fibromodulin |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3E | histone cluster 1, H3e |
| INHBE | inhibin, beta E |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCOLN3 | mucolipin 3 |
| MDM4 | MDM4, p53 regulator |
| METTL8 | methyltransferase like 8 |
| MITF | microphthalmia-associated transcription factor |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRPH | peripherin |
| QSER1 | glutamine and serine rich 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP1 | Sp1 transcription factor |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| THBS3 | thrombospondin 3 |
| THRB | thyroid hormone receptor, beta |
| TMC5 | transmembrane channel-like 5 |
| TMEM45A | transmembrane protein 45A |
| TRAIP | TRAF interacting protein |
| TUBA3C | tubulin, alpha 3c |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF329 | zinc finger protein 329 |
| ZNF428 | zinc finger protein 428 |
| ZNF516 | zinc finger protein 516 |
| ZNF532 | zinc finger protein 532 |
| ZNF665 | zinc finger protein 665 |