Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the Prestwick-664-4275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACAN | aggrecan |
ADAM12 | ADAM metallopeptidase domain 12 |
AFF1 | AF4/FMR2 family, member 1 |
AIM1L | absent in melanoma 1-like |
AKAP1 | A kinase (PRKA) anchor protein 1 |
APCS | amyloid P component, serum |
AQP4 | aquaporin 4 |
AQP6 | aquaporin 6, kidney specific |
B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
BMPR1B | bone morphogenetic protein receptor, type IB |
C10ORF12 | chromosome 10 open reading frame 12 |
C3AR1 | complement component 3a receptor 1 |
C8B | complement component 8, beta polypeptide |
CACYBP | calcyclin binding protein |
CATSPERG | catsper channel auxiliary subunit gamma |
CCDC40 | coiled-coil domain containing 40 |
CIB2 | calcium and integrin binding family member 2 |
CLEC3B | C-type lectin domain family 3, member B |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
CRHR1 | corticotropin releasing hormone receptor 1 |
CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
CUL3 | cullin 3 |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DOCK5 | dedicator of cytokinesis 5 |
DUSP7 | dual specificity phosphatase 7 |
EFHC2 | EF-hand domain (C-terminal) containing 2 |
ELL2 | elongation factor, RNA polymerase II, 2 |
EMC3 | ER membrane protein complex subunit 3 |
EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
ERC2 | ELKS/RAB6-interacting/CAST family member 2 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FOXO4 | forkhead box O4 |
GJA4 | gap junction protein, alpha 4, 37kDa |
GK | glycerol kinase |
GPR137 | G protein-coupled receptor 137 |
GYPC | glycophorin C (Gerbich blood group) |
HESX1 | HESX homeobox 1 |
HIST1H2AL | histone cluster 1, H2al |
HMGB3P1 | high mobility group box 3 pseudogene 1 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IDS | iduronate 2-sulfatase |
IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
IGL | immunoglobulin lambda locus |
IRF4 | interferon regulatory factor 4 |
KITLG | KIT ligand |
KRT86 | keratin 86, type II |
LATS1 | large tumor suppressor kinase 1 |
LRRC31 | leucine rich repeat containing 31 |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
MAPK14 | mitogen-activated protein kinase 14 |
MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
MERTK | MER proto-oncogene, tyrosine kinase |
MORN1 | MORN repeat containing 1 |
NEBL | nebulette |
NEK1 | NIMA-related kinase 1 |
OASL | 2'-5'-oligoadenylate synthetase-like |
OPN1SW | opsin 1 (cone pigments), short-wave-sensitive |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
PRAMEF12 | PRAME family member 12 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
PTPRR | protein tyrosine phosphatase, receptor type, R |
PVT1 | Pvt1 oncogene (non-protein coding) |
RARG | retinoic acid receptor, gamma |
RHO | rhodopsin |
RIF1 | replication timing regulatory factor 1 |
RIMS3 | regulating synaptic membrane exocytosis 3 |
RRAGD | Ras-related GTP binding D |
RUNDC3A | RUN domain containing 3A |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SFTPB | surfactant protein B |
SH3BP2 | SH3-domain binding protein 2 |
SH3D21 | SH3 domain containing 21 |
SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
SOCS7 | suppressor of cytokine signaling 7 |
SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
SOX2 | SRY (sex determining region Y)-box 2 |
SRF | serum response factor (c-fos serum response element-binding transcription factor) |
STAB2 | stabilin 2 |
STMN3 | stathmin-like 3 |
SYNDIG1 | synapse differentiation inducing 1 |
TACR1 | tachykinin receptor 1 |
TCN2 | transcobalamin II |
THBS1 | thrombospondin 1 |
THEMIS2 | thymocyte selection associated family member 2 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
TNNT2 | troponin T type 2 (cardiac) |
TRBV10-2 | T cell receptor beta variable 10-2 |
TRIM25 | tripartite motif containing 25 |
TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
TULP2 | tubby like protein 2 |
VCAN | versican |
WASL | Wiskott-Aldrich syndrome-like |
ZIM2 | zinc finger, imprinted 2 |
ZNF407 | zinc finger protein 407 |
Symbol | Name |
---|---|
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ADAP2 | ArfGAP with dual PH domains 2 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
ANOS1 | anosmin 1 |
ANP32A-IT1 | ANP32A intronic transcript 1 |
APOL6 | apolipoprotein L, 6 |
ATF7IP2 | activating transcription factor 7 interacting protein 2 |
BCAS3 | breast carcinoma amplified sequence 3 |
BEX1 | brain expressed, X-linked 1 |
C11ORF63 | chromosome 11 open reading frame 63 |
C11ORF80 | chromosome 11 open reading frame 80 |
C1S | complement component 1, s subcomponent |
CA11 | carbonic anhydrase XI |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CCNO | cyclin O |
CD70 | CD70 molecule |
CDADC1 | cytidine and dCMP deaminase domain containing 1 |
CLEC4E | C-type lectin domain family 4, member E |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
CORT | cortistatin |
CRMP1 | collapsin response mediator protein 1 |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
DENND3 | DENN/MADD domain containing 3 |
DOCK1 | dedicator of cytokinesis 1 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
EPN3 | epsin 3 |
ERCC2 | excision repair cross-complementation group 2 |
FAM50B | family with sequence similarity 50, member B |
FBXO31 | F-box protein 31 |
FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
FGF23 | fibroblast growth factor 23 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
GAMT | guanidinoacetate N-methyltransferase |
GLS2 | glutaminase 2 (liver, mitochondrial) |
GMPR | guanosine monophosphate reductase |
H2AFJ | H2A histone family, member J |
HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
HHLA3 | HERV-H LTR-associating 3 |
HIST1H3F | histone cluster 1, H3f |
HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
IDI2-AS1 | IDI2 antisense RNA 1 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
INF2 | inverted formin, FH2 and WH2 domain containing |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KIAA0319L | KIAA0319-like |
KLHL3 | kelch-like family member 3 |
KLHL36 | kelch-like family member 36 |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
KRT6A | keratin 6A, type II |
LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
LYRM9 | LYR motif containing 9 |
MED31 | mediator complex subunit 31 |
MMP3 | matrix metallopeptidase 3 |
NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
NTSR1 | neurotensin receptor 1 (high affinity) |
PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
PARD6A | par-6 family cell polarity regulator alpha |
PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
PGPEP1 | pyroglutamyl-peptidase I |
PHF14 | PHD finger protein 14 |
PHGDH | phosphoglycerate dehydrogenase |
PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
PODNL1 | podocan-like 1 |
POLL | polymerase (DNA directed), lambda |
PRKX | protein kinase, X-linked |
PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
RAD54L | RAD54-like (S. cerevisiae) |
RPAIN | RPA interacting protein |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
SLC46A3 | solute carrier family 46, member 3 |
SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
SPTBN2 | spectrin, beta, non-erythrocytic 2 |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
TBXAS1 | thromboxane A synthase 1 (platelet) |
TEP1 | telomerase-associated protein 1 |
TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
TH | tyrosine hydroxylase |
THBS3 | thrombospondin 3 |
TIAM2 | T-cell lymphoma invasion and metastasis 2 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TOR4A | torsin family 4, member A |
TRAF2 | TNF receptor-associated factor 2 |
TRAPPC6A | trafficking protein particle complex 6A |
UNC119 | unc-119 homolog (C. elegans) |
ZC2HC1C | zinc finger, C2HC-type containing 1C |
ZFHX2 | zinc finger homeobox 2 |
ZNF219 | zinc finger protein 219 |
ZNF276 | zinc finger protein 276 |
ZNF428 | zinc finger protein 428 |
ZNF606 | zinc finger protein 606 |