| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the Prestwick-665-2186 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACP5 | acid phosphatase 5, tartrate resistant |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| AMPD1 | adenosine monophosphate deaminase 1 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| ATP10B | ATPase, class V, type 10B |
| ATP9B | ATPase, class II, type 9B |
| BHMT | betaine--homocysteine S-methyltransferase |
| C5 | complement component 5 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD1A | CD1a molecule |
| CD8B | CD8b molecule |
| CEP164 | centrosomal protein 164kDa |
| CEP250 | centrosomal protein 250kDa |
| CHPF | chondroitin polymerizing factor |
| CREM | cAMP responsive element modulator |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DOCK9 | dedicator of cytokinesis 9 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| ELL | elongation factor RNA polymerase II |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXO5 | exonuclease 5 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF17 | fibroblast growth factor 17 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| FOXO1 | forkhead box O1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HPN | hepsin |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFITM1 | interferon induced transmembrane protein 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| LENEP | lens epithelial protein |
| LGSN | lengsin, lens protein with glutamine synthetase domain |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCAM | melanoma cell adhesion molecule |
| MIA | melanoma inhibitory activity |
| MMP19 | matrix metallopeptidase 19 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTMR1 | myotubularin related protein 1 |
| MTMR8 | myotubularin related protein 8 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NUP188 | nucleoporin 188kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHF20L1 | PHD finger protein 20-like 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAT | plasminogen activator, tissue |
| PLD3 | phospholipase D family, member 3 |
| PLEK2 | pleckstrin 2 |
| PLSCR4 | phospholipid scramblase 4 |
| PML | promyelocytic leukemia |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RALYL | RALY RNA binding protein-like |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPL7 | ribosomal protein L7 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
| SAFB2 | scaffold attachment factor B2 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SFN | stratifin |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STOML1 | stomatin (EPB72)-like 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAT | tyrosine aminotransferase |
| TEX40 | testis expressed 40 |
| THY1 | Thy-1 cell surface antigen |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM15 | tripartite motif containing 15 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TXNRD2 | thioredoxin reductase 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| VPS9D1 | VPS9 domain containing 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| AXIN1 | axin 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTBD18 | BTB (POZ) domain containing 18 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CD37 | CD37 molecule |
| CD9 | CD9 molecule |
| CES3 | carboxylesterase 3 |
| CHMP1A | charged multivesicular body protein 1A |
| CHMP6 | charged multivesicular body protein 6 |
| CKB | creatine kinase, brain |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COQ6 | coenzyme Q6 monooxygenase |
| CORO7 | coronin 7 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTRL | chymotrypsin-like |
| DENND2D | DENN/MADD domain containing 2D |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECM1 | extracellular matrix protein 1 |
| EFNA3 | ephrin-A3 |
| EPHA4 | EPH receptor A4 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGL1 | fibrinogen-like 1 |
| FHL3 | four and a half LIM domains 3 |
| FNBP1L | formin binding protein 1-like |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HPSE | heparanase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INA | internexin neuronal intermediate filament protein, alpha |
| INO80D | INO80 complex subunit D |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1107 | KIAA1107 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LMNB2 | lamin B2 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAGEF1 | melanoma antigen family F1 |
| METTL8 | methyltransferase like 8 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MVD | mevalonate (diphospho) decarboxylase |
| NKX3-2 | NK3 homeobox 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTAFR | platelet-activating factor receptor |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RETN | resistin |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RWDD2A | RWD domain containing 2A |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCPEP1 | serine carboxypeptidase 1 |
| SETD1A | SET domain containing 1A |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLFN12 | schlafen family member 12 |
| SMYD5 | SMYD family member 5 |
| SP1 | Sp1 transcription factor |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| STAT5A | signal transducer and activator of transcription 5A |
| STRN | striatin, calmodulin binding protein |
| SV2A | synaptic vesicle glycoprotein 2A |
| SYNJ2BP | synaptojanin 2 binding protein |
| TCTN1 | tectonic family member 1 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THEM6 | thioesterase superfamily member 6 |
| TRAC | T cell receptor alpha constant |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBB2A | tubulin, beta 2A class IIa |
| UNC119 | unc-119 homolog (C. elegans) |
| VNN1 | vanin 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF324 | zinc finger protein 324 |
| ZNF668 | zinc finger protein 668 |
| ZNF747 | zinc finger protein 747 |
