| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the Prestwick-665-7380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AAK1 | AP2 associated kinase 1 |
| ABAT | 4-aminobutyrate aminotransferase |
| ACVR1B | activin A receptor, type IB |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATP11A | ATPase, class VI, type 11A |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AURKA | aurora kinase A |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BMP2K | BMP2 inducible kinase |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CD7 | CD7 molecule |
| CDC42 | cell division cycle 42 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CES2 | carboxylesterase 2 |
| CLDN11 | claudin 11 |
| CLDN17 | claudin 17 |
| COL8A2 | collagen, type VIII, alpha 2 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DRP2 | dystrophin related protein 2 |
| EDN1 | endothelin 1 |
| EGF | epidermal growth factor |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FLOT2 | flotillin 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GMPR | guanosine monophosphate reductase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPM6B | glycoprotein M6B |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTPBP1 | GTP binding protein 1 |
| HES2 | hes family bHLH transcription factor 2 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H4E | histone cluster 1, H4e |
| HOXA7 | homeobox A7 |
| HOXC4 | homeobox C4 |
| HP | haptoglobin |
| HSF2 | heat shock transcription factor 2 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IFT74 | intraflagellar transport 74 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KRT6B | keratin 6B, type II |
| LMNA | lamin A/C |
| LPAR2 | lysophosphatidic acid receptor 2 |
| LPIN1 | lipin 1 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NCOR2 | nuclear receptor corepressor 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NF1 | neurofibromin 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRF1 | nuclear respiratory factor 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PASK | PAS domain containing serine/threonine kinase |
| PCM1 | pericentriolar material 1 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POGZ | pogo transposable element with ZNF domain |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB6A | RAB6A, member RAS oncogene family |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RGR | retinal G protein coupled receptor |
| RHOT2 | ras homolog family member T2 |
| RNF122 | ring finger protein 122 |
| RPL7 | ribosomal protein L7 |
| RUNX1 | runt-related transcription factor 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAPBP | TAP binding protein (tapasin) |
| TBCD | tubulin folding cofactor D |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TMC6 | transmembrane channel-like 6 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| UBE3B | ubiquitin protein ligase E3B |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YY2 | YY2 transcription factor |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF197 | zinc finger protein 197 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACVR2B | activin A receptor, type IIB |
| ADCY7 | adenylate cyclase 7 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AEN | apoptosis enhancing nuclease |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APH1B | APH1B gamma secretase subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDH7 | cadherin 7, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK9 | cyclin-dependent kinase 9 |
| CDON | cell adhesion associated, oncogene regulated |
| CENPT | centromere protein T |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLEC10A | C-type lectin domain family 10, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EN2 | engrailed homeobox 2 |
| ERF | Ets2 repressor factor |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM114A2 | family with sequence similarity 114, member A2 |
| GATA6 | GATA binding protein 6 |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H3H | histone cluster 1, H3h |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KIAA0232 | KIAA0232 |
| KIAA1551 | KIAA1551 |
| KIF16B | kinesin family member 16B |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LINS | lines homolog (Drosophila) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MANEA | mannosidase, endo-alpha |
| MBD5 | methyl-CpG binding domain protein 5 |
| MEIS1 | Meis homeobox 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NBEAL2 | neurobeachin-like 2 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLSCR4 | phospholipid scramblase 4 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIN1 | Ras and Rab interactor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCAI | suppressor of cancer cell invasion |
| SCARA3 | scavenger receptor class A, member 3 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD6 | SET domain containing 6 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNTA1 | syntrophin, alpha 1 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM2 | transmembrane protein 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM38B | transmembrane protein 38B |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TOR4A | torsin family 4, member A |
| TRIM9 | tripartite motif containing 9 |
| WDR18 | WD repeat domain 18 |
| WDR91 | WD repeat domain 91 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF34 | zinc finger protein 34 |
| ZNF668 | zinc finger protein 668 |
| ZNF671 | zinc finger protein 671 |
