| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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189 genes differentially expressed following the Prestwick-674-2179 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| AHI1 | Abelson helper integration site 1 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APC | adenomatous polyposis coli |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOC4 | apolipoprotein C-IV |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP10B | ATPase, class V, type 10B |
| ATP13A2 | ATPase type 13A2 |
| BCR | breakpoint cluster region |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CBX8 | chromobox homolog 8 |
| CD84 | CD84 molecule |
| COL10A1 | collagen, type X, alpha 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CXCR1 | chemokine (C-X-C motif) receptor 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOPEY2 | dopey family member 2 |
| DSC3 | desmocollin 3 |
| DST | dystonin |
| F11R | F11 receptor |
| FBXO22 | F-box protein 22 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FYB | FYN binding protein |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GPR107 | G protein-coupled receptor 107 |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| HRH2 | histamine receptor H2 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| INO80B | INO80 complex subunit B |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KLHL36 | kelch-like family member 36 |
| LIMK1 | LIM domain kinase 1 |
| LMTK1 | lemur tail kinase 1 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NPEPL1 | aminopeptidase-like 1 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDGFRL | platelet-derived growth factor receptor-like |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G3 | phospholipase A2, group III |
| PLAC4 | placenta-specific 4 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PODXL2 | podocalyxin-like 2 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RDX | radixin |
| RUNDC3B | RUN domain containing 3B |
| RUNX1 | runt-related transcription factor 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNPH | syntaphilin |
| SPAG11A | sperm associated antigen 11A |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STX1A | syntaxin 1A (brain) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMEM63A | transmembrane protein 63A |
| TRADD | TNFRSF1A-associated via death domain |
| TRMT61A | tRNA methyltransferase 61A |
| UBOX5 | U-box domain containing 5 |
| UPP1 | uridine phosphorylase 1 |
| VCAN | versican |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF286A | zinc finger protein 286A |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACPP | acid phosphatase, prostate |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARRB1 | arrestin, beta 1 |
| ASPN | asporin |
| BNC2 | basonuclin 2 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX4 | chromobox homolog 4 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD101 | CD101 molecule |
| CD300C | CD300c molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPB | centromere protein B, 80kDa |
| CFP | complement factor properdin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTRL | chymotrypsin-like |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EPHA4 | EPH receptor A4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FMOD | fibromodulin |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR27 | G protein-coupled receptor 27 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HP | haptoglobin |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL4R | interleukin 4 receptor |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PER3 | period circadian clock 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLCD1 | phospholipase C, delta 1 |
| PLP1 | proteolipid protein 1 |
| PMCH | pro-melanin-concentrating hormone |
| POM121 | POM121 transmembrane nucleoporin |
| RAB13 | RAB13, member RAS oncogene family |
| RAB17 | RAB17, member RAS oncogene family |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF121 | ring finger protein 121 |
| RPL10L | ribosomal protein L10-like |
| SCD5 | stearoyl-CoA desaturase 5 |
| SERTAD3 | SERTA domain containing 3 |
| SGCE | sarcoglycan, epsilon |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNX15 | sorting nexin 15 |
| SP1 | Sp1 transcription factor |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STAT5A | signal transducer and activator of transcription 5A |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| THBS4 | thrombospondin 4 |
| THEM6 | thioesterase superfamily member 6 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM120B | transmembrane protein 120B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM22 | tripartite motif containing 22 |
| TRIM45 | tripartite motif containing 45 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3D | tubulin, alpha 3d |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UPB1 | ureidopropionase, beta |
| ZNF225 | zinc finger protein 225 |
| ZNF250 | zinc finger protein 250 |
| ZNF493 | zinc finger protein 493 |
| ZNF574 | zinc finger protein 574 |
| ZNF671 | zinc finger protein 671 |
