| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the Prestwick-675-2187 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABLIM1 | actin binding LIM protein 1 |
| ACOT7 | acyl-CoA thioesterase 7 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| B9D1 | B9 protein domain 1 |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CD200 | CD200 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK10 | cyclin-dependent kinase 10 |
| CLTA | clathrin, light chain A |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCHS2 | dachsous cadherin-related 2 |
| DCTN2 | dynactin 2 (p50) |
| DEFA4 | defensin, alpha 4, corticostatin |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPT | dermatopontin |
| EGR4 | early growth response 4 |
| FBXO4 | F-box protein 4 |
| FLOT1 | flotillin 1 |
| FOXP3 | forkhead box P3 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GJC2 | gap junction protein, gamma 2, 47kDa |
| GP5 | glycoprotein V (platelet) |
| GSTA1 | glutathione S-transferase alpha 1 |
| GTPBP1 | GTP binding protein 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HFE | hemochromatosis |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOMER3 | homer scaffolding protein 3 |
| HSF1 | heat shock transcription factor 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL10 | interleukin 10 |
| IL1R2 | interleukin 1 receptor, type II |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KDM8 | lysine (K)-specific demethylase 8 |
| KL | klotho |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LTB4R | leukotriene B4 receptor |
| MAGEA5 | melanoma antigen family A5 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP4 | microtubule-associated protein 4 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP7 | matrix metallopeptidase 7 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| PADI4 | peptidyl arginine deiminase, type IV |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| PAPPA2 | pappalysin 2 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLCH1 | phospholipase C, eta 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYGB | phosphorylase, glycogen; brain |
| RB1 | retinoblastoma 1 |
| RBMY2FP | RNA binding motif protein, Y-linked, family 2, member F pseudogene |
| RHOC | ras homolog family member C |
| SCHIP1 | schwannomin interacting protein 1 |
| SERHL2 | serine hydrolase-like 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SP110 | SP110 nuclear body protein |
| SYN2 | synapsin II |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TFF2 | trefoil factor 2 |
| TNNI3 | troponin I type 3 (cardiac) |
| TPM1 | tropomyosin 1 (alpha) |
| TRIM15 | tripartite motif containing 15 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| TSPAN4 | tetraspanin 4 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AHCTF1 | AT hook containing transcription factor 1 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BBC3 | BCL2 binding component 3 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTBD18 | BTB (POZ) domain containing 18 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CBX7 | chromobox homolog 7 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CFP | complement factor properdin |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNTLN | centlein, centrosomal protein |
| COL9A2 | collagen, type IX, alpha 2 |
| CORT | cortistatin |
| CTSD | cathepsin D |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHA4 | EPH receptor A4 |
| EPHB6 | EPH receptor B6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM63A | family with sequence similarity 63, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FES | FES proto-oncogene, tyrosine kinase |
| FMOD | fibromodulin |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR22 | G protein-coupled receptor 22 |
| GPR27 | G protein-coupled receptor 27 |
| GRPR | gastrin-releasing peptide receptor |
| HCFC2 | host cell factor C2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AM | histone cluster 1, H2am |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HPSE | heparanase |
| HS1BP3 | HCLS1 binding protein 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KIAA0754 | KIAA0754 |
| KIAA1107 | KIAA1107 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAK | male germ cell-associated kinase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RAB3A | RAB3A, member RAS oncogene family |
| RFPL3 | ret finger protein-like 3 |
| RFXAP | regulatory factor X-associated protein |
| RHOB | ras homolog family member B |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF2 | ring finger protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SIK1 | salt-inducible kinase 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SP1 | Sp1 transcription factor |
| SPATA1 | spermatogenesis associated 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| STAT5A | signal transducer and activator of transcription 5A |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIGD6 | tigger transposable element derived 6 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM8A | transmembrane protein 8A |
| TRAF1 | TNF receptor-associated factor 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA4B | tubulin, alpha 4b |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF197 | zinc finger protein 197 |
