| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-675-7381 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AMPH | amphiphysin |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF7IP | activating transcription factor 7 interacting protein |
| AXIN1 | axin 1 |
| BRCA1 | breast cancer 1, early onset |
| CABIN1 | calcineurin binding protein 1 |
| CCNT2 | cyclin T2 |
| CDC14B | cell division cycle 14B |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CLDN11 | claudin 11 |
| CNN1 | calponin 1, basic, smooth muscle |
| COPA | coatomer protein complex, subunit alpha |
| CRYL1 | crystallin, lambda 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DPP4 | dipeptidyl-peptidase 4 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUZ | fuzzy planar cell polarity protein |
| FYB | FYN binding protein |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPC3 | glypican 3 |
| GPR137 | G protein-coupled receptor 137 |
| GUK1 | guanylate kinase 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3I | histone cluster 1, H3i |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IL32 | interleukin 32 |
| ING4 | inhibitor of growth family, member 4 |
| ITGB5 | integrin, beta 5 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOXL2 | lysyl oxidase-like 2 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED16 | mediator complex subunit 16 |
| MED18 | mediator complex subunit 18 |
| MIIP | migration and invasion inhibitory protein |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMRN2 | multimerin 2 |
| MR1 | major histocompatibility complex, class I-related |
| MTA1 | metastasis associated 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NNMT | nicotinamide N-methyltransferase |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPAS1 | neuronal PAS domain protein 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLCG1 | phospholipase C, gamma 1 |
| PMP2 | peripheral myelin protein 2 |
| PODNL1 | podocan-like 1 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTEN | phosphatase and tensin homolog |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB6B | RAB6B, member RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RIN3 | Ras and Rab interactor 3 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RPL7 | ribosomal protein L7 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SOD3 | superoxide dismutase 3, extracellular |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STK3 | serine/threonine kinase 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TLE4 | transducin-like enhancer of split 4 |
| TOP3B | topoisomerase (DNA) III beta |
| TRIM2 | tripartite motif containing 2 |
| TRIM25 | tripartite motif containing 25 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE3B | ubiquitin protein ligase E3B |
| UBQLN4 | ubiquilin 4 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDR33 | WD repeat domain 33 |
| ZNF197 | zinc finger protein 197 |
| ZNF219 | zinc finger protein 219 |
| ZNF222 | zinc finger protein 222 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABHD17B | abhydrolase domain containing 17B |
| ABHD8 | abhydrolase domain containing 8 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMC6 | armadillo repeat containing 6 |
| ATP10D | ATPase, class V, type 10D |
| ATP13A2 | ATPase type 13A2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC68 | coiled-coil domain containing 68 |
| CD70 | CD70 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP70 | centrosomal protein 70kDa |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC10A | C-type lectin domain family 10, member A |
| CLEC16A | C-type lectin domain family 16, member A |
| CTSK | cathepsin K |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DENND1A | DENN/MADD domain containing 1A |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNMBP | dynamin binding protein |
| EML4 | echinoderm microtubule associated protein like 4 |
| EN2 | engrailed homeobox 2 |
| EPN3 | epsin 3 |
| EVPL | envoplakin |
| EXOC3 | exocyst complex component 3 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FHOD1 | formin homology 2 domain containing 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GALK1 | galactokinase 1 |
| GLCE | glucuronic acid epimerase |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 |
| GRAMD4 | GRAM domain containing 4 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3G | histone cluster 1, H3g |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| ISL1 | ISL LIM homeobox 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1462 | KIAA1462 |
| KRT34 | keratin 34, type I |
| KRT6A | keratin 6A, type II |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LRRC61 | leucine rich repeat containing 61 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MB | myoglobin |
| MMP1 | matrix metallopeptidase 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| NID2 | nidogen 2 (osteonidogen) |
| NINL | ninein-like |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NXPH4 | neurexophilin 4 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| RASA2 | RAS p21 protein activator 2 |
| RNF2 | ring finger protein 2 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TEP1 | telomerase-associated protein 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM2 | transmembrane protein 2 |
| TMEM53 | transmembrane protein 53 |
| TMEM8B | transmembrane protein 8B |
| TPCN1 | two pore segment channel 1 |
| TSPAN12 | tetraspanin 12 |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| VEGFB | vascular endothelial growth factor B |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF10 | zinc finger protein 10 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF253 | zinc finger protein 253 |
| ZNF350 | zinc finger protein 350 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZXDC | ZXD family zinc finger C |
