| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the Prestwick-682-6638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| ABAT | 4-aminobutyrate aminotransferase |
| ACVRL1 | activin A receptor type II-like 1 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMACR | alpha-methylacyl-CoA racemase |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BEX1 | brain expressed, X-linked 1 |
| C3AR1 | complement component 3a receptor 1 |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD58 | CD58 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHI3L2 | chitinase 3-like 2 |
| CNN1 | calponin 1, basic, smooth muscle |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DUSP2 | dual specificity phosphatase 2 |
| ESR1 | estrogen receptor 1 |
| FCMR | Fc fragment of IgM receptor |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRMD4B | FERM domain containing 4B |
| GAS7 | growth arrest-specific 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR135 | G protein-coupled receptor 135 |
| HABP4 | hyaluronan binding protein 4 |
| HFE | hemochromatosis |
| HIST1H2BM | histone cluster 1, H2bm |
| HMG20B | high mobility group 20B |
| HMHB1 | histocompatibility (minor) HB-1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGHD | immunoglobulin heavy constant delta |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLF13 | Kruppel-like factor 13 |
| KLK13 | kallikrein-related peptidase 13 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LRRN3 | leucine rich repeat neuronal 3 |
| MED25 | mediator complex subunit 25 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MPZ | myelin protein zero |
| MTMR3 | myotubularin related protein 3 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NMUR1 | neuromedin U receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRF1 | nuclear respiratory factor 1 |
| NRXN3 | neurexin 3 |
| NUP88 | nucleoporin 88kDa |
| NXF2 | nuclear RNA export factor 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OLFM4 | olfactomedin 4 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDHB3 | protocadherin beta 3 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| POU1F1 | POU class 1 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRSS50 | protease, serine, 50 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTRF | polymerase I and transcript release factor |
| RGR | retinal G protein coupled receptor |
| RGS12 | regulator of G-protein signaling 12 |
| RGS6 | regulator of G-protein signaling 6 |
| RPLP2 | ribosomal protein, large, P2 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFTPA2 | surfactant protein A2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNN | stannin |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SYT13 | synaptotagmin XIII |
| TACR1 | tachykinin receptor 1 |
| TCF12 | transcription factor 12 |
| THPO | thrombopoietin |
| TMPRSS4 | transmembrane protease, serine 4 |
| TTC12 | tetratricopeptide repeat domain 12 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UPK3B | uroplakin 3B |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACKR3 | atypical chemokine receptor 3 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AMT | aminomethyltransferase |
| APH1B | APH1B gamma secretase subunit |
| BEND5 | BEN domain containing 5 |
| BEX4 | brain expressed, X-linked 4 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC94 | coiled-coil domain containing 94 |
| CCNO | cyclin O |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNN2 | calponin 2 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDN | dendrin |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EN2 | engrailed homeobox 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCC | Fanconi anemia, complementation group C |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRAMD1C | GRAM domain containing 1C |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXA4 | homeobox A4 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0319L | KIAA0319-like |
| KIAA0922 | KIAA0922 |
| KLF2 | Kruppel-like factor 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LIPG | lipase, endothelial |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAGEA6 | melanoma antigen family A6 |
| MDM4 | MDM4, p53 regulator |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MLYCD | malonyl-CoA decarboxylase |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PICK1 | protein interacting with PRKCA 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLL | polymerase (DNA directed), lambda |
| PRAME | preferentially expressed antigen in melanoma |
| PRSS8 | protease, serine, 8 |
| RAB17 | RAB17, member RAS oncogene family |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SYCP2 | synaptonemal complex protein 2 |
| TAOK1 | TAO kinase 1 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMC6 | transmembrane channel-like 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TPCN1 | two pore segment channel 1 |
| TRIM16 | tripartite motif containing 16 |
| TRIM66 | tripartite motif containing 66 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA4B | tubulin, alpha 4b |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TWISTNB | TWIST neighbor |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF227 | zinc finger protein 227 |
| ZNF286A | zinc finger protein 286A |
| ZNF528 | zinc finger protein 528 |
| ZNF549 | zinc finger protein 549 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF675 | zinc finger protein 675 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF768 | zinc finger protein 768 |
