| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the Prestwick-685-3683 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHI1 | Abelson helper integration site 1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANK2 | ankyrin 2, neuronal |
| APC2 | adenomatosis polyposis coli 2 |
| ARMC4 | armadillo repeat containing 4 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| AVIL | advillin |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C6 | complement component 6 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CFAP74 | cilia and flagella associated protein 74 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLEC7A | C-type lectin domain family 7, member A |
| COL7A1 | collagen, type VII, alpha 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| DCLK2 | doublecortin-like kinase 2 |
| DCTN2 | dynactin 2 (p50) |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EPS8L1 | EPS8-like 1 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO21 | F-box protein 21 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GFI1 | growth factor independent 1 transcription repressor |
| GGT1 | gamma-glutamyltransferase 1 |
| GPC3 | glypican 3 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPR27 | G protein-coupled receptor 27 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| GTPBP1 | GTP binding protein 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H2AB | histone cluster 1, H2ab |
| HR | hair growth associated |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KAZN | kazrin, periplakin interacting protein |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| MC5R | melanocortin 5 receptor |
| MEF2D | myocyte enhancer factor 2D |
| MEOX1 | mesenchyme homeobox 1 |
| MMP11 | matrix metallopeptidase 11 |
| MST1L | macrophage stimulating 1-like |
| MT4 | metallothionein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO15A | myosin XVA |
| MYO9B | myosin IXB |
| MYT1 | myelin transcription factor 1 |
| NPTXR | neuronal pentraxin receptor |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NRP1 | neuropilin 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| ODAM | odontogenic, ameloblast asssociated |
| OVOL1 | ovo-like zinc finger 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLXDC1 | plexin domain containing 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTEN | phosphatase and tensin homolog |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB26 | RAB26, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RHEB | Ras homolog enriched in brain |
| RYR3 | ryanodine receptor 3 |
| SERHL2 | serine hydrolase-like 2 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SFTPB | surfactant protein B |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPANXC | SPANX family, member C |
| SPHK2 | sphingosine kinase 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLX1 | T-cell leukemia homeobox 1 |
| TP53 | tumor protein p53 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TXK | TXK tyrosine kinase |
| ULBP1 | UL16 binding protein 1 |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMT | aminomethyltransferase |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCNT1 | cyclin T1 |
| CES3 | carboxylesterase 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CISH | cytokine inducible SH2-containing protein |
| CLK1 | CDC-like kinase 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM120C | family with sequence similarity 120C |
| FANCC | Fanconi anemia, complementation group C |
| FANCE | Fanconi anemia, complementation group E |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGL1 | fibrinogen-like 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRPR | gastrin-releasing peptide receptor |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| IFI6 | interferon, alpha-inducible protein 6 |
| IMPACT | impact RWD domain protein |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JAM3 | junctional adhesion molecule 3 |
| KIAA1551 | KIAA1551 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIMD2 | LIM domain containing 2 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGEA5 | melanoma antigen family A5 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTA2 | metastasis associated 1 family, member 2 |
| NEK11 | NIMA-related kinase 11 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDZK1 | PDZ domain containing 1 |
| PGP | phosphoglycolate phosphatase |
| PGPEP1 | pyroglutamyl-peptidase I |
| PICK1 | protein interacting with PRKCA 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RNF122 | ring finger protein 122 |
| RNF170 | ring finger protein 170 |
| RPA4 | replication protein A4, 30kDa |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMO | smoothened, frizzled class receptor |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TLR2 | toll-like receptor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TPK1 | thiamin pyrophosphokinase 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| WDR4 | WD repeat domain 4 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP30 | ZFP30 zinc finger protein |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF264 | zinc finger protein 264 |
| ZNF329 | zinc finger protein 329 |
| ZNF552 | zinc finger protein 552 |
| ZNF611 | zinc finger protein 611 |
| ZNF749 | zinc finger protein 749 |
| ZNF76 | zinc finger protein 76 |
