| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the Prestwick-685-4705 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADCY1 | adenylate cyclase 1 (brain) |
| AIM2 | absent in melanoma 2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATM | ATM serine/threonine kinase |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| CABP2 | calcium binding protein 2 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCDC181 | coiled-coil domain containing 181 |
| CCKAR | cholecystokinin A receptor |
| CDC14A | cell division cycle 14A |
| CES1 | carboxylesterase 1 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL4A4 | collagen, type IV, alpha 4 |
| CTBP2 | C-terminal binding protein 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLX2 | distal-less homeobox 2 |
| DNM3 | dynamin 3 |
| DST | dystonin |
| FBN1 | fibrillin 1 |
| FOXA2 | forkhead box A2 |
| GAP43 | growth associated protein 43 |
| GFI1 | growth factor independent 1 transcription repressor |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPSM3 | G-protein signaling modulator 3 |
| H2AFX | H2A histone family, member X |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HSPB3 | heat shock 27kDa protein 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFNA14 | interferon, alpha 14 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LTB4R | leukotriene B4 receptor |
| MALL | mal, T-cell differentiation protein-like |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MID1 | midline 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTSS1L | metastasis suppressor 1-like |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEFM | neurofilament, medium polypeptide |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPR1 | natriuretic peptide receptor 1 |
| NPVF | neuropeptide VF precursor |
| OLFM4 | olfactomedin 4 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBBP4 | retinoblastoma binding protein 4 |
| RPS3A | ribosomal protein S3A |
| SAFB2 | scaffold attachment factor B2 |
| SIX1 | SIX homeobox 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SMIM14 | small integral membrane protein 14 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TAAR5 | trace amine associated receptor 5 |
| TACR1 | tachykinin receptor 1 |
| TCF3 | transcription factor 3 |
| THOC5 | THO complex 5 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLL2 | tolloid-like 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNXB | tenascin XB |
| TPMT | thiopurine S-methyltransferase |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF230 | zinc finger protein 230 |
| ZNF362 | zinc finger protein 362 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD17B | abhydrolase domain containing 17B |
| AFF4 | AF4/FMR2 family, member 4 |
| AGO1 | argonaute RISC catalytic component 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDHR2 | cadherin-related family member 2 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRYGC | crystallin, gamma C |
| CTAGE5 | CTAGE family, member 5 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DENND4A | DENN/MADD domain containing 4A |
| EFNA3 | ephrin-A3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FILIP1L | filamin A interacting protein 1-like |
| FRK | fyn-related Src family tyrosine kinase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPC3 | glypican 3 |
| GPR27 | G protein-coupled receptor 27 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFT22 | intraflagellar transport 22 |
| IPO8 | importin 8 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF1 | interferon regulatory factor 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIF13A | kinesin family member 13A |
| KLF13 | Kruppel-like factor 13 |
| KLHL28 | kelch-like family member 28 |
| KRT31 | keratin 31, type I |
| LHX6 | LIM homeobox 6 |
| LRRC20 | leucine rich repeat containing 20 |
| LYRM9 | LYR motif containing 9 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MUC3A | mucin 3A, cell surface associated |
| NCS1 | neuronal calcium sensor 1 |
| NEUROD1 | neuronal differentiation 1 |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NLK | nemo-like kinase |
| NSUN3 | NOP2/Sun domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PITX2 | paired-like homeodomain 2 |
| PMCH | pro-melanin-concentrating hormone |
| PMEL | premelanosome protein |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB3D | RAB3D, member RAS oncogene family |
| REEP4 | receptor accessory protein 4 |
| RPGRIP1L | RPGRIP1-like |
| S100A4 | S100 calcium binding protein A4 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SKI | SKI proto-oncogene |
| SNX15 | sorting nexin 15 |
| SNX16 | sorting nexin 16 |
| SP1 | Sp1 transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBX19 | T-box 19 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM254 | transmembrane protein 254 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIM25 | tripartite motif containing 25 |
| TRIM52 | tripartite motif containing 52 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBB2B | tubulin, beta 2B class IIb |
| UBOX5 | U-box domain containing 5 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR44 | WD repeat domain 44 |
| ZNF124 | zinc finger protein 124 |
| ZNF468 | zinc finger protein 468 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
