| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the Prestwick-689-5816 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARMC6 | armadillo repeat containing 6 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASTN2 | astrotactin 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CA1 | carbonic anhydrase I |
| CACFD1 | calcium channel flower domain containing 1 |
| CCNT2 | cyclin T2 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP68 | centrosomal protein 68kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP6 | charged multivesicular body protein 6 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DPYSL3 | dihydropyrimidinase-like 3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ETV7 | ets variant 7 |
| FAM50B | family with sequence similarity 50, member B |
| FGFR4 | fibroblast growth factor receptor 4 |
| FH | fumarate hydratase |
| FKBP15 | FK506 binding protein 15, 133kDa |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GPM6B | glycoprotein M6B |
| GPR137 | G protein-coupled receptor 137 |
| GSK3A | glycogen synthase kinase 3 alpha |
| ID2B | inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| ITGB8 | integrin, beta 8 |
| KIF5C | kinesin family member 5C |
| KLHL20 | kelch-like family member 20 |
| KRT17 | keratin 17, type I |
| KRT34 | keratin 34, type I |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NADK | NAD kinase |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEBL | nebulette |
| NKX3-2 | NK3 homeobox 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OPTN | optineurin |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEX6 | peroxisomal biogenesis factor 6 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB31 | RAB31, member RAS oncogene family |
| RIMBP2 | RIMS binding protein 2 |
| RNF122 | ring finger protein 122 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SSBP3 | single stranded DNA binding protein 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR3 | synaptogyrin 3 |
| TADA2A | transcriptional adaptor 2A |
| TAGLN3 | transgelin 3 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN8 | tetraspanin 8 |
| UBTD1 | ubiquitin domain containing 1 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF408 | zinc finger protein 408 |
| ZNF571 | zinc finger protein 571 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BEX1 | brain expressed, X-linked 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNT1 | cyclin T1 |
| CCS | copper chaperone for superoxide dismutase |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHKB | choline kinase beta |
| COPG1 | coatomer protein complex, subunit gamma 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EMC6 | ER membrane protein complex subunit 6 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPPK1 | epiplakin 1 |
| FAM131A | family with sequence similarity 131, member A |
| FAM53B | family with sequence similarity 53, member B |
| FBXO46 | F-box protein 46 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLCN | folliculin |
| GID4 | GID complex subunit 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC4 | histone deacetylase 4 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BC | histone cluster 1, H2bc |
| HMOX1 | heme oxygenase 1 |
| IFT54 | intraflagellar transport 54 |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RB | interleukin 17 receptor B |
| KIFC1 | kinesin family member C1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLC2 | kinesin light chain 2 |
| LAMB2 | laminin, beta 2 (laminin S) |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAGEF1 | melanoma antigen family F1 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MED22 | mediator complex subunit 22 |
| MGC12488 | |
| NINJ1 | ninjurin 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRR15L | proline rich 15-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| RAB3A | RAB3A, member RAS oncogene family |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNTA1 | syntrophin, alpha 1 |
| STBD1 | starch binding domain 1 |
| STEAP4 | STEAP family member 4 |
| STIM1 | stromal interaction molecule 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TKFC | triokinase/FMN cyclase |
| TMEM209 | transmembrane protein 209 |
| TMEM212 | transmembrane protein 212 |
| UNKL | unkempt family zinc finger-like |
| VASH2 | vasohibin 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF385D | zinc finger protein 385D |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
