| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the Prestwick-691-2813 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT7 | acyl-CoA thioesterase 7 |
| ADORA1 | adenosine A1 receptor |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BTD | biotinidase |
| CACTIN | cactin, spliceosome C complex subunit |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC68 | coiled-coil domain containing 68 |
| CDC14A | cell division cycle 14A |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL19A1 | collagen, type XIX, alpha 1 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FLOT1 | flotillin 1 |
| GLS | glutaminase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR1 | G protein-coupled receptor 1 |
| GSN | gelsolin |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| IRS2 | insulin receptor substrate 2 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KIAA0754 | KIAA0754 |
| KIAA1109 | KIAA1109 |
| LENEP | lens epithelial protein |
| LMAN1 | lectin, mannose-binding, 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAL | mal, T-cell differentiation protein |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| METTL16 | methyltransferase like 16 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MSMB | microseminoprotein, beta- |
| MTRF1L | mitochondrial translational release factor 1-like |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NF1 | neurofibromin 1 |
| NPFF | neuropeptide FF-amide peptide precursor |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| ONECUT2 | one cut homeobox 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PER2 | period circadian clock 2 |
| PHF14 | PHD finger protein 14 |
| PKN2 | protein kinase N2 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKCI | protein kinase C, iota |
| PVR | poliovirus receptor |
| RB1 | retinoblastoma 1 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF19B | ring finger protein 19B |
| RPL35A | ribosomal protein L35a |
| RXRB | retinoid X receptor, beta |
| SECISBP2 | SECIS binding protein 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIRT5 | sirtuin 5 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNRK | SNF related kinase |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SYNC | syncoilin, intermediate filament protein |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAOK2 | TAO kinase 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMC6 | transmembrane channel-like 6 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA3D | tubulin, alpha 3d |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF235 | zinc finger protein 235 |
| ZNF236 | zinc finger protein 236 |
| ZNF41 | zinc finger protein 41 |
| ZNF771 | zinc finger protein 771 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ATP10D | ATPase, class V, type 10D |
| BMP15 | bone morphogenetic protein 15 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1QB | complement component 1, q subcomponent, B chain |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDO1 | cysteine dioxygenase type 1 |
| CEP41 | centrosomal protein 41kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP6 | charged multivesicular body protein 6 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIC | capicua transcriptional repressor |
| CNTN1 | contactin 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSF1R | colony stimulating factor 1 receptor |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EXOSC1 | exosome component 1 |
| FADS2 | fatty acid desaturase 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXI1 | forkhead box I1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3E | histone cluster 1, H3e |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| INHBE | inhibin, beta E |
| IRS4 | insulin receptor substrate 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF2 | Kruppel-like factor 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGEA6 | melanoma antigen family A6 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MGC12488 | |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3A | mucin 3A, cell surface associated |
| NCALD | neurocalcin delta |
| NCF2 | neutrophil cytosolic factor 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NRSN2 | neurensin 2 |
| ONECUT1 | one cut homeobox 1 |
| PC | pyruvate carboxylase |
| PICK1 | protein interacting with PRKCA 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRPH | peripherin |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RGS19 | regulator of G-protein signaling 19 |
| RPL32 | ribosomal protein L32 |
| RPS15A | ribosomal protein S15a |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STRA6 | stimulated by retinoic acid 6 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBC1D22B | TBC1 domain family, member 22B |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCP10 | t-complex 10 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THRB | thyroid hormone receptor, beta |
| TMEM177 | transmembrane protein 177 |
| TNS2 | tensin 2 |
| TOR4A | torsin family 4, member A |
| TSGA10 | testis specific, 10 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UPP1 | uridine phosphorylase 1 |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF665 | zinc finger protein 665 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
