Prestwick-692-2165 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the Prestwick-692-2165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADD2 adducin 2 (beta)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGTPBP1 ATP/GTP binding protein 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APAF1 apoptotic peptidase activating factor 1
APOM apolipoprotein M
ARNT aryl hydrocarbon receptor nuclear translocator
ATP9B ATPase, class II, type 9B
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1ORF95 chromosome 1 open reading frame 95
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCDC85B coiled-coil domain containing 85B
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEND1 cell cycle exit and neuronal differentiation 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPA4 carboxypeptidase A4
CREM cAMP responsive element modulator
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIAPH2 diaphanous-related formin 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA5 ephrin-A5
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FLOT1 flotillin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GALC galactosylceramidase
GHRHR growth hormone releasing hormone receptor
GIPR gastric inhibitory polypeptide receptor
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSN gelsolin
HES1 hes family bHLH transcription factor 1
HIC2 hypermethylated in cancer 2
HIST1H2BO histone cluster 1, H2bo
HIST1H3I histone cluster 1, H3i
HLA-DMB major histocompatibility complex, class II, DM beta
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IFNA16 interferon, alpha 16
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD2 potassium channel tetramerization domain containing 2
KDM8 lysine (K)-specific demethylase 8
LRRC16A leucine rich repeat containing 16A
MAP4 microtubule-associated protein 4
MBNL2 muscleblind-like splicing regulator 2
MLF1 myeloid leukemia factor 1
MRPS12 mitochondrial ribosomal protein S12
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEK9 NIMA-related kinase 9
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PICK1 protein interacting with PRKCA 1
POU5F1B POU class 5 homeobox 1B
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PVR poliovirus receptor
PYGB phosphorylase, glycogen; brain
RAB11B RAB11B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHOT2 ras homolog family member T2
RNF126P1 ring finger protein 126 pseudogene 1
RUNX1 runt-related transcription factor 1
RWDD3 RWD domain containing 3
SHB Src homology 2 domain containing adaptor protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A30 solute carrier family 25, member 30
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPRR1B small proline-rich protein 1B
STOML1 stomatin (EPB72)-like 1
STS steroid sulfatase (microsomal), isozyme S
SV2B synaptic vesicle glycoprotein 2B
SYNDIG1 synapse differentiation inducing 1
TCP10 t-complex 10
TMC7 transmembrane channel-like 7
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPSAB1 tryptase alpha/beta 1
UBE2I ubiquitin-conjugating enzyme E2I
UBR4 ubiquitin protein ligase E3 component n-recognin 4
WDR25 WD repeat domain 25
WDR59 WD repeat domain 59
ZBTB7A zinc finger and BTB domain containing 7A
ZMYND8 zinc finger, MYND-type containing 8
ZNF442 zinc finger protein 442
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
A2M alpha-2-macroglobulin
ABHD11 abhydrolase domain containing 11
ADGRE2 adhesion G protein-coupled receptor E2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AVPI1 arginine vasopressin-induced 1
BBC3 BCL2 binding component 3
BCL2L2 BCL2-like 2
BIRC3 baculoviral IAP repeat containing 3
C16ORF45 chromosome 16 open reading frame 45
C2ORF27A chromosome 2 open reading frame 27A
C5AR1 complement component 5a receptor 1
CCDC106 coiled-coil domain containing 106
CCDC85C coiled-coil domain containing 85C
CD37 CD37 molecule
CD9 CD9 molecule
CDKL3 cyclin-dependent kinase-like 3
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLEC2D C-type lectin domain family 2, member D
CLEC4E C-type lectin domain family 4, member E
CORT cortistatin
CTNNBIP1 catenin, beta interacting protein 1
CXCR2 chemokine (C-X-C motif) receptor 2
DOC2A double C2-like domains, alpha
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
EPHA4 EPH receptor A4
EPHB6 EPH receptor B6
ERCC2 excision repair cross-complementation group 2
ERICH1 glutamate-rich 1
FAM188A family with sequence similarity 188, member A
FBXO22 F-box protein 22
FDXR ferredoxin reductase
GGTLC1 gamma-glutamyltransferase light chain 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRIP2 glutamate receptor interacting protein 2
GSTA3 glutathione S-transferase alpha 3
GSTT1 glutathione S-transferase theta 1
HIST1H1T histone cluster 1, H1t
HIST1H2AE histone cluster 1, H2ae
HIST1H4D histone cluster 1, H4d
HOXA1 homeobox A1
HOXA5 homeobox A5
HYAL3 hyaluronoglucosaminidase 3
KIAA0754 KIAA0754
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LOC157562 uncharacterized LOC157562
LOC730101 uncharacterized LOC730101
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K7CL MAP3K7 C-terminal like
MOCS3 molybdenum cofactor synthesis 3
MX1 MX dynamin-like GTPase 1
MYOZ3 myozenin 3
NECAB3 N-terminal EF-hand calcium binding protein 3
NTSR1 neurotensin receptor 1 (high affinity)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLTP phospholipid transfer protein
PMP22 peripheral myelin protein 22
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RANBP17 RAN binding protein 17
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRAGB Ras-related GTP binding B
SETD1A SET domain containing 1A
SIDT1 SID1 transmembrane family, member 1
SLAMF7 SLAM family member 7
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLITRK5 SLIT and NTRK-like family, member 5
SOCS7 suppressor of cytokine signaling 7
SPATA20 spermatogenesis associated 20
STARD13 StAR-related lipid transfer (START) domain containing 13
STBD1 starch binding domain 1
STON1 stonin 1
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
TFF2 trefoil factor 2
TMEM184B transmembrane protein 184B
TREM2 triggering receptor expressed on myeloid cells 2
TSC22D4 TSC22 domain family, member 4
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USB1 U6 snRNA biogenesis 1
XAB2 XPA binding protein 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF137P zinc finger protein 137, pseudogene
ZNF185 zinc finger protein 185 (LIM domain)