| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the Prestwick-692-4599 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY9 | adenylate cyclase 9 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| APC | adenomatous polyposis coli |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APOM | apolipoprotein M |
| ATP10A | ATPase, class V, type 10A |
| ATP13A3 | ATPase type 13A3 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C5 | complement component 5 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD82 | CD82 molecule |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLTB | clathrin, light chain B |
| COL14A1 | collagen, type XIV, alpha 1 |
| CORO2B | coronin, actin binding protein, 2B |
| CREM | cAMP responsive element modulator |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DOCK6 | dedicator of cytokinesis 6 |
| EPS8L1 | EPS8-like 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM134B | family with sequence similarity 134, member B |
| FBXO11 | F-box protein 11 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GTF2I | general transcription factor IIi |
| HEMK1 | HemK methyltransferase family member 1 |
| ING4 | inhibitor of growth family, member 4 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCK | IQ motif containing K |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| ITGB8 | integrin, beta 8 |
| JAK2 | Janus kinase 2 |
| KIAA1109 | KIAA1109 |
| KRT15 | keratin 15, type I |
| LAMC2 | laminin, gamma 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCL1 | myeloid cell leukemia 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MTA2 | metastasis associated 1 family, member 2 |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NUP160 | nucleoporin 160kDa |
| OGDHL | oxoglutarate dehydrogenase-like |
| OLFML2B | olfactomedin-like 2B |
| PALM | paralemmin |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PEX3 | peroxisomal biogenesis factor 3 |
| PHF14 | PHD finger protein 14 |
| PHF20 | PHD finger protein 20 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RHEB | Ras homolog enriched in brain |
| RIOK3 | RIO kinase 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RRAGB | Ras-related GTP binding B |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPAG16 | sperm associated antigen 16 |
| STK3 | serine/threonine kinase 3 |
| TADA2A | transcriptional adaptor 2A |
| TCF4 | transcription factor 4 |
| TRIM14 | tripartite motif containing 14 |
| TROVE2 | TROVE domain family, member 2 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VAMP4 | vesicle-associated membrane protein 4 |
| WDR76 | WD repeat domain 76 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFX | zinc finger protein, X-linked |
| ZNF141 | zinc finger protein 141 |
| ZNF225 | zinc finger protein 225 |
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARMC6 | armadillo repeat containing 6 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BNC1 | basonuclin 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA9 | carbonic anhydrase IX |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLDN17 | claudin 17 |
| CLSTN3 | calsyntenin 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DUSP9 | dual specificity phosphatase 9 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM184A | family with sequence similarity 184, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FZD10 | frizzled class receptor 10 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GMPR | guanosine monophosphate reductase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IL2 | interleukin 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KIAA0319L | KIAA0319-like |
| KRT86 | keratin 86, type II |
| LIMD2 | LIM domain containing 2 |
| LIPG | lipase, endothelial |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC257152 | uncharacterized LOC257152 |
| MAP2 | microtubule-associated protein 2 |
| MED9 | mediator complex subunit 9 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLA2G15 | phospholipase A2, group XV |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| POLH | polymerase (DNA directed), eta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PROX1 | prospero homeobox 1 |
| RFPL3 | ret finger protein-like 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCG2 | secretogranin II |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SP1 | Sp1 transcription factor |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIGD6 | tigger transposable element derived 6 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TOM1 | target of myb1 (chicken) |
| TRAF2 | TNF receptor-associated factor 2 |
| TUBA4B | tubulin, alpha 4b |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZIC3 | Zic family member 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF253 | zinc finger protein 253 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF428 | zinc finger protein 428 |
| ZNF749 | zinc finger protein 749 |
| ZNF768 | zinc finger protein 768 |
