| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-857-6635 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AFF3 | AF4/FMR2 family, member 3 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AREG | amphiregulin |
| ARMC4 | armadillo repeat containing 4 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BGN | biglycan |
| BTG2 | BTG family, member 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CELF2 | CUGBP, Elav-like family member 2 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| DCN | decorin |
| DLX4 | distal-less homeobox 4 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EPYC | epiphycan |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FILIP1L | filamin A interacting protein 1-like |
| FOXO1 | forkhead box O1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HBE1 | hemoglobin, epsilon 1 |
| HDAC6 | histone deacetylase 6 |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXA1 | homeobox A1 |
| HPSE2 | heparanase 2 (inactive) |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT122 | intraflagellar transport 122 |
| ING4 | inhibitor of growth family, member 4 |
| IRX4 | iroquois homeobox 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF12 | Kruppel-like factor 12 |
| KRT33A | keratin 33A, type I |
| LAMC2 | laminin, gamma 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC48 | leucine rich repeat containing 48 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTCP1 | mature T-cell proliferation 1 |
| NDNF | neuron-derived neurotrophic factor |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| PAPPA2 | pappalysin 2 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDPN | podoplanin |
| PHF20 | PHD finger protein 20 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PML | promyelocytic leukemia |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RARB | retinoic acid receptor, beta |
| RGS14 | regulator of G-protein signaling 14 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNJ1 | synaptojanin 1 |
| TAOK2 | TAO kinase 2 |
| TBCD | tubulin folding cofactor D |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP10 | t-complex 10 |
| TCP10L | t-complex 10-like |
| TLK1 | tousled-like kinase 1 |
| TLR2 | toll-like receptor 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPM3 | tropomyosin 3 |
| USP46 | ubiquitin specific peptidase 46 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WWOX | WW domain containing oxidoreductase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XDH | xanthine dehydrogenase |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF24 | zinc finger protein 24 |
| ZNF440 | zinc finger protein 440 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADTRP | androgen-dependent TFPI-regulating protein |
| AMT | aminomethyltransferase |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN15 | calpain 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CFHR2 | complement factor H-related 2 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CISH | cytokine inducible SH2-containing protein |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DFNB31 | deafness, autosomal recessive 31 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DSPP | dentin sialophosphoprotein |
| DUSP8 | dual specificity phosphatase 8 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNA3 | ephrin-A3 |
| ERCC4 | excision repair cross-complementation group 4 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAS8 | growth arrest-specific 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GRAMD1C | GRAM domain containing 1C |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAMP | hepcidin antimicrobial peptide |
| HDAC9 | histone deacetylase 9 |
| HIST1H1D | histone cluster 1, H1d |
| IL2 | interleukin 2 |
| KIAA0319L | KIAA0319-like |
| KIAA0922 | KIAA0922 |
| KLC2 | kinesin light chain 2 |
| KLHL4 | kelch-like family member 4 |
| KRT20 | keratin 20, type I |
| KRT6A | keratin 6A, type II |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTC4S | leukotriene C4 synthase |
| MCC | mutated in colorectal cancers |
| MDFI | MyoD family inhibitor |
| MDM4 | MDM4, p53 regulator |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOB3B | MOB kinase activator 3B |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYL9 | myosin, light chain 9, regulatory |
| MYOZ3 | myozenin 3 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NKX3-2 | NK3 homeobox 2 |
| NME5 | NME/NM23 family member 5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PICK1 | protein interacting with PRKCA 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAC8 | placenta-specific 8 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PQLC2 | PQ loop repeat containing 2 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTK6 | protein tyrosine kinase 6 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCG2 | secretogranin II |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| STAG3 | stromal antigen 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TEP1 | telomerase-associated protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM159 | transmembrane protein 159 |
| TMEM242 | transmembrane protein 242 |
| TUBA4B | tubulin, alpha 4b |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VNN1 | vanin 1 |
| WDR4 | WD repeat domain 4 |
| ZNF205 | zinc finger protein 205 |
| ZNF268 | zinc finger protein 268 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF623 | zinc finger protein 623 |
| ZNF652 | zinc finger protein 652 |
