| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the Prestwick-860-3378 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADORA1 | adenosine A1 receptor |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ART1 | ADP-ribosyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| BDKRB2 | bradykinin receptor B2 |
| CA4 | carbonic anhydrase IV |
| CCDC64 | coiled-coil domain containing 64 |
| CD101 | CD101 molecule |
| CD52 | CD52 molecule |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CEP162 | centrosomal protein 162kDa |
| CERS4 | ceramide synthase 4 |
| CES1 | carboxylesterase 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ECE1 | endothelin converting enzyme 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERP44 | endoplasmic reticulum protein 44 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FOXO4 | forkhead box O4 |
| FRZB | frizzled-related protein |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GFER | growth factor, augmenter of liver regeneration |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GK | glycerol kinase |
| GM2A | GM2 ganglioside activator |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTP1 | glutathione S-transferase pi 1 |
| HIST1H3E | histone cluster 1, H3e |
| HNMT | histamine N-methyltransferase |
| HOXA10 | homeobox A10 |
| HSF1 | heat shock transcription factor 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL2RB | interleukin 2 receptor, beta |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KERA | keratocan |
| KLHL3 | kelch-like family member 3 |
| LAMB4 | laminin, beta 4 |
| LENEP | lens epithelial protein |
| LOXL2 | lysyl oxidase-like 2 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MEF2C | myocyte enhancer factor 2C |
| MID1 | midline 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3B | mucin 3B, cell surface associated |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYOF | myoferlin |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPTXR | neuronal pentraxin receptor |
| OGFR | opioid growth factor receptor |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKCB | protein kinase C, beta |
| RBM17 | RNA binding motif protein 17 |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SERHL2 | serine hydrolase-like 2 |
| SFRP4 | secreted frizzled-related protein 4 |
| SFTPB | surfactant protein B |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SNX13 | sorting nexin 13 |
| SPON2 | spondin 2, extracellular matrix protein |
| STK16 | serine/threonine kinase 16 |
| TBX6 | T-box 6 |
| TBXA2R | thromboxane A2 receptor |
| TEF | thyrotrophic embryonic factor |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPM2 | tropomyosin 2 (beta) |
| TUBB7P | tubulin, beta 7, pseudogene |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WIZ | widely interspaced zinc finger motifs |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AFF4 | AF4/FMR2 family, member 4 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BMP15 | bone morphogenetic protein 15 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNK | cyclin K |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CIC | capicua transcriptional repressor |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CXORF56 | chromosome X open reading frame 56 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DYSF | dysferlin |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC6 | excision repair cross-complementation group 6 |
| FAM131A | family with sequence similarity 131, member A |
| FAM184A | family with sequence similarity 184, member A |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GLCE | glucuronic acid epimerase |
| GMPR | guanosine monophosphate reductase |
| GPR143 | G protein-coupled receptor 143 |
| GPR21 | G protein-coupled receptor 21 |
| GPR27 | G protein-coupled receptor 27 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HIST1H4F | histone cluster 1, H4f |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT54 | intraflagellar transport 54 |
| IMPACT | impact RWD domain protein |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF6 | interferon regulatory factor 6 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LHX6 | LIM homeobox 6 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MITF | microphthalmia-associated transcription factor |
| MTCL1 | microtubule crosslinking factor 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PODNL1 | podocan-like 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMIM14 | small integral membrane protein 14 |
| STIM1 | stromal interaction molecule 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TEX40 | testis expressed 40 |
| TH | tyrosine hydroxylase |
| TMPRSS4 | transmembrane protease, serine 4 |
| TMSB15A | thymosin beta 15a |
| TRIM36 | tripartite motif containing 36 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3D | tubulin, alpha 3d |
| WDR33 | WD repeat domain 33 |
| XDH | xanthine dehydrogenase |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF230 | zinc finger protein 230 |
| ZNF446 | zinc finger protein 446 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |