Prestwick-864-4113 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the Prestwick-864-4113 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATN1 atrophin 1
AVPR1B arginine vasopressin receptor 1B
C11ORF16 chromosome 11 open reading frame 16
C5AR2 complement component 5a receptor 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CARD10 caspase recruitment domain family, member 10
CARD14 caspase recruitment domain family, member 14
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL27 chemokine (C-C motif) ligand 27
CDK14 cyclin-dependent kinase 14
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CLEC2B C-type lectin domain family 2, member B
COL4A6 collagen, type IV, alpha 6
COL5A2 collagen, type V, alpha 2
CRY2 cryptochrome circadian clock 2
CYLD cylindromatosis (turban tumor syndrome)
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCN decorin
DFNB31 deafness, autosomal recessive 31
ELL2 elongation factor, RNA polymerase II, 2
EMP3 epithelial membrane protein 3
EPHB1 EPH receptor B1
ESR1 estrogen receptor 1
ETV7 ets variant 7
FAM214B family with sequence similarity 214, member B
FLT3LG fms-related tyrosine kinase 3 ligand
FOXI1 forkhead box I1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFER growth factor, augmenter of liver regeneration
GIF gastric intrinsic factor (vitamin B synthesis)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HAL histidine ammonia-lyase
HIPK3 homeodomain interacting protein kinase 3
HLA-DOB major histocompatibility complex, class II, DO beta
ICA1 islet cell autoantigen 1, 69kDa
IFT27 intraflagellar transport 27
IGFBP5 insulin-like growth factor binding protein 5
IL15 interleukin 15
ITM2C integral membrane protein 2C
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KEL Kell blood group, metallo-endopeptidase
KIAA1107 KIAA1107
KLHDC8A kelch domain containing 8A
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LY9 lymphocyte antigen 9
MAL mal, T-cell differentiation protein
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MEFV Mediterranean fever
MMP25 matrix metallopeptidase 25
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
NKX2-5 NK2 homeobox 5
NOX1 NADPH oxidase 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OXCT2 3-oxoacid CoA transferase 2
PAPPA2 pappalysin 2
PDE10A phosphodiesterase 10A
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF1 PHD finger protein 1
PLAT plasminogen activator, tissue
PQLC2 PQ loop repeat containing 2
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCAN2 regulator of calcineurin 2
RIN1 Ras and Rab interactor 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETBP1 SET binding protein 1
SH3BP2 SH3-domain binding protein 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC6A16 solute carrier family 6, member 16
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUGP1 SURP and G patch domain containing 1
SYN3 synapsin III
SYNDIG1 synapse differentiation inducing 1
TCEAL2 transcription elongation factor A (SII)-like 2
THY1 Thy-1 cell surface antigen
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
VSIG4 V-set and immunoglobulin domain containing 4
YOD1 YOD1 deubiquitinase
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF223 zinc finger protein 223
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C4ORF29 chromosome 4 open reading frame 29
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPRIN2 caprin family member 2
CDK20 cyclin-dependent kinase 20
CFAP69 cilia and flagella associated protein 69
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CRABP1 cellular retinoic acid binding protein 1
CTNNBL1 catenin, beta like 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP6 elongator acetyltransferase complex subunit 6
ERCC4 excision repair cross-complementation group 4
FAM46C family with sequence similarity 46, member C
FKBP14 FK506 binding protein 14, 22 kDa
GADD45G growth arrest and DNA-damage-inducible, gamma
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HOXC10 homeobox C10
INO80D INO80 complex subunit D
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF2 Kruppel-like factor 2
LOC100287590 uncharacterized LOC100287590
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP2 low density lipoprotein receptor-related protein 2
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MVD mevalonate (diphospho) decarboxylase
NLRX1 NLR family member X1
NOL12 nucleolar protein 12
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSGIN1 oxidative stress induced growth inhibitor 1
OSTF1 osteoclast stimulating factor 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN3 perilipin 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PYCR1 pyrroline-5-carboxylate reductase 1
RAB11B RAB11B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SETD1A SET domain containing 1A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM45A transmembrane protein 45A
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
WDR7 WD repeat domain 7
WDR76 WD repeat domain 76
WFDC2 WAP four-disulfide core domain 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF286A zinc finger protein 286A
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF701 zinc finger protein 701
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZW10 zw10 kinetochore protein