| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the Prestwick-864-4113 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATN1 | atrophin 1 |
| AVPR1B | arginine vasopressin receptor 1B |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C5AR2 | complement component 5a receptor 2 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CARD10 | caspase recruitment domain family, member 10 |
| CARD14 | caspase recruitment domain family, member 14 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDK14 | cyclin-dependent kinase 14 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 |
| CLEC2B | C-type lectin domain family 2, member B |
| COL4A6 | collagen, type IV, alpha 6 |
| COL5A2 | collagen, type V, alpha 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DCN | decorin |
| DFNB31 | deafness, autosomal recessive 31 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EMP3 | epithelial membrane protein 3 |
| EPHB1 | EPH receptor B1 |
| ESR1 | estrogen receptor 1 |
| ETV7 | ets variant 7 |
| FAM214B | family with sequence similarity 214, member B |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXI1 | forkhead box I1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GFER | growth factor, augmenter of liver regeneration |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| HAL | histidine ammonia-lyase |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-DOB | major histocompatibility complex, class II, DO beta |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFT27 | intraflagellar transport 27 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL15 | interleukin 15 |
| ITM2C | integral membrane protein 2C |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA1107 | KIAA1107 |
| KLHDC8A | kelch domain containing 8A |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LY9 | lymphocyte antigen 9 |
| MAL | mal, T-cell differentiation protein |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MEFV | Mediterranean fever |
| MMP25 | matrix metallopeptidase 25 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NKX2-5 | NK2 homeobox 5 |
| NOX1 | NADPH oxidase 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAPPA2 | pappalysin 2 |
| PDE10A | phosphodiesterase 10A |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHF1 | PHD finger protein 1 |
| PLAT | plasminogen activator, tissue |
| PQLC2 | PQ loop repeat containing 2 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCAN2 | regulator of calcineurin 2 |
| RIN1 | Ras and Rab interactor 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SETBP1 | SET binding protein 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SUGP1 | SURP and G patch domain containing 1 |
| SYN3 | synapsin III |
| SYNDIG1 | synapse differentiation inducing 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THY1 | Thy-1 cell surface antigen |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| YOD1 | YOD1 deubiquitinase |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF223 | zinc finger protein 223 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPRIN2 | caprin family member 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP69 | cilia and flagella associated protein 69 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTNNBL1 | catenin, beta like 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM46C | family with sequence similarity 46, member C |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| HOXC10 | homeobox C10 |
| INO80D | INO80 complex subunit D |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF2 | Kruppel-like factor 2 |
| LOC100287590 | uncharacterized LOC100287590 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LYRM9 | LYR motif containing 9 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MVD | mevalonate (diphospho) decarboxylase |
| NLRX1 | NLR family member X1 |
| NOL12 | nucleolar protein 12 |
| NRSN2 | neurensin 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OSTF1 | osteoclast stimulating factor 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLIN3 | perilipin 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB11B | RAB11B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SETD1A | SET domain containing 1A |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SP1 | Sp1 transcription factor |
| SPRYD7 | SPRY domain containing 7 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAOK1 | TAO kinase 1 |
| TDRD1 | tudor domain containing 1 |
| TEP1 | telomerase-associated protein 1 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM45A | transmembrane protein 45A |
| TRAIP | TRAF interacting protein |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TWF2 | twinfilin actin binding protein 2 |
| UBQLN4 | ubiquilin 4 |
| UBXN6 | UBX domain protein 6 |
| WDR7 | WD repeat domain 7 |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF286A | zinc finger protein 286A |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF675 | zinc finger protein 675 |
| ZNF701 | zinc finger protein 701 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZW10 | zw10 kinetochore protein |