| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the Prestwick-967-2925 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADCK2 | aarF domain containing kinase 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CA8 | carbonic anhydrase VIII |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC132 | coiled-coil domain containing 132 |
| CDC14B | cell division cycle 14B |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DMC1 | DNA meiotic recombinase 1 |
| DOCK6 | dedicator of cytokinesis 6 |
| DSPP | dentin sialophosphoprotein |
| E2F1 | E2F transcription factor 1 |
| EGR4 | early growth response 4 |
| EHD1 | EH-domain containing 1 |
| FAM163A | family with sequence similarity 163, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FCHO1 | FCH domain only 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GLI3 | GLI family zinc finger 3 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC11 | histone deacetylase 11 |
| HDAC6 | histone deacetylase 6 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HNF1B | HNF1 homeobox B |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| IL2RB | interleukin 2 receptor, beta |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIAA0226L | KIAA0226-like |
| KLK2 | kallikrein-related peptidase 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT81 | keratin 81, type II |
| LAMB3 | laminin, beta 3 |
| LDLR | low density lipoprotein receptor |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRC15 | leucine rich repeat containing 15 |
| MAL | mal, T-cell differentiation protein |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED25 | mediator complex subunit 25 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLXIP | MLX interacting protein |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NNAT | neuronatin |
| NOX4 | NADPH oxidase 4 |
| OGFR | opioid growth factor receptor |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RASL11B | RAS-like, family 11, member B |
| RGS5 | regulator of G-protein signaling 5 |
| RPH3A | rabphilin 3A |
| RPL37A | ribosomal protein L37a |
| RRBP1 | ribosome binding protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBCD | tubulin folding cofactor D |
| TBX2 | T-box 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TGFB1 | transforming growth factor, beta 1 |
| TIMELESS | timeless circadian clock |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSKS | testis-specific serine kinase substrate |
| TSPAN9 | tetraspanin 9 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VDAC3 | voltage-dependent anion channel 3 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF688 | zinc finger protein 688 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACPP | acid phosphatase, prostate |
| ANO10 | anoctamin 10 |
| APOL6 | apolipoprotein L, 6 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATF6 | activating transcription factor 6 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C5 | complement component 5 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| DENND2D | DENN/MADD domain containing 2D |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMBP | dynamin binding protein |
| DTWD1 | DTW domain containing 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM3C | family with sequence similarity 3, member C |
| FANCF | Fanconi anemia, complementation group F |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FES | FES proto-oncogene, tyrosine kinase |
| GCH1 | GTP cyclohydrolase 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HOXA1 | homeobox A1 |
| HOXA5 | homeobox A5 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INHBE | inhibin, beta E |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| ISOC2 | isochorismatase domain containing 2 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KPTN | kaptin (actin binding protein) |
| LIMD2 | LIM domain containing 2 |
| LOC157562 | uncharacterized LOC157562 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MIR22HG | MIR22 host gene |
| MRPL28 | mitochondrial ribosomal protein L28 |
| MYH15 | myosin, heavy chain 15 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PARPBP | PARP1 binding protein |
| PITX2 | paired-like homeodomain 2 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PSKH1 | protein serine kinase H1 |
| PTH2R | parathyroid hormone 2 receptor |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PYGB | phosphorylase, glycogen; brain |
| RGS19 | regulator of G-protein signaling 19 |
| RNF31 | ring finger protein 31 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCAI | suppressor of cancer cell invasion |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SKI | SKI proto-oncogene |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SSFA2 | sperm specific antigen 2 |
| THAP10 | THAP domain containing 10 |
| TMEM104 | transmembrane protein 104 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TROAP | trophinin associated protein |
| TTF2 | transcription termination factor, RNA polymerase II |
| UPP1 | uridine phosphorylase 1 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF250 | zinc finger protein 250 |
| ZNF254 | zinc finger protein 254 |
| ZNF280D | zinc finger protein 280D |
| ZNF665 | zinc finger protein 665 |
| ZNF667 | zinc finger protein 667 |
| ZNF804A | zinc finger protein 804A |
