| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the Prestwick-981-6504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTN2 | actinin, alpha 2 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AFF2 | AF4/FMR2 family, member 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOM | apolipoprotein M |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARTN | artemin |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC25A | cell division cycle 25A |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLPS | colipase, pancreatic |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL4A1 | collagen, type IV, alpha 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CUL4B | cullin 4B |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| EFNA3 | ephrin-A3 |
| EFNB3 | ephrin-B3 |
| ELAC2 | elaC ribonuclease Z 2 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAS | Fas cell surface death receptor |
| FPR1 | formyl peptide receptor 1 |
| GALC | galactosylceramidase |
| GMPR | guanosine monophosphate reductase |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HPGDS | hematopoietic prostaglandin D synthase |
| IPO8 | importin 8 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LMF2 | lipase maturation factor 2 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MST1R | macrophage stimulating 1 receptor |
| MTA1 | metastasis associated 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NPR3 | natriuretic peptide receptor 3 |
| NUDCD3 | NudC domain containing 3 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PARD6B | par-6 family cell polarity regulator beta |
| PAX2 | paired box 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PML | promyelocytic leukemia |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PTRF | polymerase I and transcript release factor |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RARG | retinoic acid receptor, gamma |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SAFB | scaffold attachment factor B |
| SBF1 | SET binding factor 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYNDIG1 | synapse differentiation inducing 1 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TAOK1 | TAO kinase 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TLN1 | talin 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TPMT | thiopurine S-methyltransferase |
| TRBC1 | T cell receptor beta constant 1 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF134 | zinc finger protein 134 |
| ZNF224 | zinc finger protein 224 |
| ZNF34 | zinc finger protein 34 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACYP2 | acylphosphatase 2, muscle type |
| AFAP1 | actin filament associated protein 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5AR2 | complement component 5a receptor 2 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CEL | carboxyl ester lipase |
| CENPQ | centromere protein Q |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNN2 | calponin 2 |
| CUL9 | cullin 9 |
| DACH1 | dachshund family transcription factor 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNM1 | dynamin 1 |
| DSPP | dentin sialophosphoprotein |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EMID1 | EMI domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| H1F0 | H1 histone family, member 0 |
| HCFC1 | host cell factor C1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IL4R | interleukin 4 receptor |
| IRX4 | iroquois homeobox 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13B | kinesin family member 13B |
| KLHL12 | kelch-like family member 12 |
| KLHL25 | kelch-like family member 25 |
| LAMA3 | laminin, alpha 3 |
| LENEP | lens epithelial protein |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LOXL3 | lysyl oxidase-like 3 |
| LYRM9 | LYR motif containing 9 |
| MAP1S | microtubule-associated protein 1S |
| MED9 | mediator complex subunit 9 |
| MPI | mannose phosphate isomerase |
| MTSS1L | metastasis suppressor 1-like |
| MUC3A | mucin 3A, cell surface associated |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHB3 | protocadherin beta 3 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLD2 | phospholipase D2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKX | protein kinase, X-linked |
| PRSS53 | protease, serine, 53 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RANGRF | RAN guanine nucleotide release factor |
| RARS | arginyl-tRNA synthetase |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDC3 | syndecan 3 |
| SECTM1 | secreted and transmembrane 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH2D4A | SH2 domain containing 4A |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STEAP4 | STEAP family member 4 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCTN1 | tectonic family member 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF573 | zinc finger protein 573 |
| ZNF586 | zinc finger protein 586 |
| ZNF611 | zinc finger protein 611 |