| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the Prestwick-983-3141 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABHD6 | abhydrolase domain containing 6 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AREG | amphiregulin |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARL4C | ADP-ribosylation factor-like 4C |
| AXL | AXL receptor tyrosine kinase |
| BIN1 | bridging integrator 1 |
| BMP6 | bone morphogenetic protein 6 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD38 | CD38 molecule |
| CD86 | CD86 molecule |
| CHN2 | chimerin 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| FADS3 | fatty acid desaturase 3 |
| FOXA1 | forkhead box A1 |
| FOXO1 | forkhead box O1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNLY | granulysin |
| GPR183 | G protein-coupled receptor 183 |
| GRAMD1B | GRAM domain containing 1B |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HP | haptoglobin |
| HPSE | heparanase |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI30 | interferon, gamma-inducible protein 30 |
| IL11 | interleukin 11 |
| IL1R1 | interleukin 1 receptor, type I |
| IL7R | interleukin 7 receptor |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KYNU | kynureninase |
| LAMB3 | laminin, beta 3 |
| LXN | latexin |
| MCAM | melanoma cell adhesion molecule |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MOB3B | MOB kinase activator 3B |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MXRA8 | matrix-remodelling associated 8 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PINK1 | PTEN induced putative kinase 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRL | prolactin |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| QDPR | quinoid dihydropteridine reductase |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SATB1 | SATB homeobox 1 |
| SDC2 | syndecan 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH2D2A | SH2 domain containing 2A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SMOX | spermine oxidase |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STAT4 | signal transducer and activator of transcription 4 |
| SYCP2 | synaptonemal complex protein 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TKTL1 | transketolase-like 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBB2A | tubulin, beta 2A class IIa |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ANKRD55 | ankyrin repeat domain 55 |
| ANXA3 | annexin A3 |
| ARRB1 | arrestin, beta 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA1 | cyclin A1 |
| CD69 | CD69 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DKC1 | dyskeratosis congenita 1, dyskerin |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| EBNA1BP2 | EBNA1 binding protein 2 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOSC5 | exosome component 5 |
| FAM216A | family with sequence similarity 216, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FKBP5 | FK506 binding protein 5 |
| FLT3 | fms-related tyrosine kinase 3 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| HOPX | HOP homeobox |
| IFITM3 | interferon induced transmembrane protein 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INHBE | inhibin, beta E |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KIAA0020 | KIAA0020 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| METTL1 | methyltransferase like 1 |
| MPI | mannose phosphate isomerase |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPAN | peter pan homolog (Drosophila) |
| PRDM13 | PR domain containing 13 |
| PRTN3 | proteinase 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPIA | ribose 5-phosphate isomerase A |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SRM | spermidine synthase |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEC | tec protein tyrosine kinase |
| TERT | telomerase reverse transcriptase |
| TMEM104 | transmembrane protein 104 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR12 | WD repeat domain 12 |
| WDR46 | WD repeat domain 46 |
| WT1 | Wilms tumor 1 |
| XYLT2 | xylosyltransferase II |
| YARS | tyrosyl-tRNA synthetase |
| ZNF692 | zinc finger protein 692 |
