| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the Prestwick-984-4948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIF1 | allograft inflammatory factor 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATF6B | activating transcription factor 6 beta |
| AUTS2 | autism susceptibility candidate 2 |
| BLNK | B-cell linker |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC85C | coiled-coil domain containing 85C |
| CD8A | CD8a molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CES3 | carboxylesterase 3 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DLG5 | discs, large homolog 5 (Drosophila) |
| DOCK6 | dedicator of cytokinesis 6 |
| DRD2 | dopamine receptor D2 |
| DSPP | dentin sialophosphoprotein |
| EDNRA | endothelin receptor type A |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| FAM46C | family with sequence similarity 46, member C |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FHL1 | four and a half LIM domains 1 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GP5 | glycoprotein V (platelet) |
| HBB | hemoglobin, beta |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H4D | histone cluster 1, H4d |
| HOMER3 | homer scaffolding protein 3 |
| HOXD11 | homeobox D11 |
| HR | hair growth associated |
| IDS | iduronate 2-sulfatase |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| LHX2 | LIM homeobox 2 |
| LMF2 | lipase maturation factor 2 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MEF2D | myocyte enhancer factor 2D |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMP3 | matrix metallopeptidase 3 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTRF1L | mitochondrial translational release factor 1-like |
| NOP16 | NOP16 nucleolar protein |
| NPR3 | natriuretic peptide receptor 3 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OLFML2A | olfactomedin-like 2A |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 |
| PAX5 | paired box 5 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLCG1 | phospholipase C, gamma 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POPDC3 | popeye domain containing 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PRMT2IP | PRMT2 interacting protein |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RB1 | retinoblastoma 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBM5 | RNA binding motif protein 5 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SETBP1 | SET binding protein 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRT5 | sirtuin 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SRCAP | Snf2-related CREBBP activator protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TREX1 | three prime repair exonuclease 1 |
| TRGV5 | T cell receptor gamma variable 5 |
| TRIM36 | tripartite motif containing 36 |
| TUBA4B | tubulin, alpha 4b |
| USP19 | ubiquitin specific peptidase 19 |
| USP22 | ubiquitin specific peptidase 22 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WSCD1 | WSC domain containing 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF446 | zinc finger protein 446 |
| ZNF682 | zinc finger protein 682 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATP13A2 | ATPase type 13A2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CCDC186 | coiled-coil domain containing 186 |
| CFD | complement factor D (adipsin) |
| CLDN1 | claudin 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COMMD9 | COMM domain containing 9 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFHD2 | EF-hand domain family, member D2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCHO1 | FCH domain only 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HIST1H2AM | histone cluster 1, H2am |
| HOXA4 | homeobox A4 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL22 | interleukin 22 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUNB | jun B proto-oncogene |
| KIAA0754 | KIAA0754 |
| LHX6 | LIM homeobox 6 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MB | myoglobin |
| MED24 | mediator complex subunit 24 |
| MED9 | mediator complex subunit 9 |
| METTL16 | methyltransferase like 16 |
| MICALL2 | MICAL-like 2 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| N4BP3 | NEDD4 binding protein 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| ONECUT2 | one cut homeobox 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGBD5 | piggyBac transposable element derived 5 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLL | polymerase (DNA directed), lambda |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RLN1 | relaxin 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2B3 | SH2B adaptor protein 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TRIM21 | tripartite motif containing 21 |
| TRIM25 | tripartite motif containing 25 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN5 | tetraspanin 5 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3C | tubulin, alpha 3c |
| UCN | urocortin |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| WDR4 | WD repeat domain 4 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF304 | zinc finger protein 304 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF552 | zinc finger protein 552 |
| ZNF557 | zinc finger protein 557 |
| ZNF639 | zinc finger protein 639 |
| ZNF750 | zinc finger protein 750 |
