Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the Prestwick-984-7323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACVR1B | activin A receptor, type IB |
AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
ALS2CL | ALS2 C-terminal like |
AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
ATP9A | ATPase, class II, type 9A |
AURKA | aurora kinase A |
B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
C11ORF63 | chromosome 11 open reading frame 63 |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CCP110 | centriolar coiled coil protein 110kDa |
CD4 | CD4 molecule |
CD44 | CD44 molecule (Indian blood group) |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
DAGLA | diacylglycerol lipase, alpha |
DCTN1 | dynactin 1 |
DICER1 | dicer 1, ribonuclease type III |
DUSP10 | dual specificity phosphatase 10 |
DUSP9 | dual specificity phosphatase 9 |
DUX1 | double homeobox 1 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EHD1 | EH-domain containing 1 |
EPHA1 | EPH receptor A1 |
EPHB1 | EPH receptor B1 |
EPOR | erythropoietin receptor |
EVA1B | eva-1 homolog B (C. elegans) |
FBXL18 | F-box and leucine-rich repeat protein 18 |
FOXG1 | forkhead box G1 |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GK | glycerol kinase |
GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
HOMER3 | homer scaffolding protein 3 |
HOXB5 | homeobox B5 |
KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
LOC257152 | uncharacterized LOC257152 |
LRP12 | low density lipoprotein receptor-related protein 12 |
LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
MTERF4 | mitochondrial transcription termination factor 4 |
MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
MTMR3 | myotubularin related protein 3 |
MUC1 | mucin 1, cell surface associated |
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
NCKIPSD | NCK interacting protein with SH3 domain |
NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
NF1 | neurofibromin 1 |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NMT2 | N-myristoyltransferase 2 |
NUP88 | nucleoporin 88kDa |
PCDH12 | protocadherin 12 |
PDCD2 | programmed cell death 2 |
PDE8B | phosphodiesterase 8B |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
PLIN2 | perilipin 2 |
PMEL | premelanosome protein |
PML | promyelocytic leukemia |
POLL | polymerase (DNA directed), lambda |
POM121 | POM121 transmembrane nucleoporin |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PRDX2 | peroxiredoxin 2 |
PROS1 | protein S (alpha) |
PRUNE2 | prune homolog 2 (Drosophila) |
RAB36 | RAB36, member RAS oncogene family |
RBM19 | RNA binding motif protein 19 |
RNF122 | ring finger protein 122 |
RPL10L | ribosomal protein L10-like |
RPS2 | ribosomal protein S2 |
RREB1 | ras responsive element binding protein 1 |
SAMD4A | sterile alpha motif domain containing 4A |
SBF1 | SET binding factor 1 |
SDC2 | syndecan 2 |
SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
SIGLEC8 | sialic acid binding Ig-like lectin 8 |
SLC17A2 | solute carrier family 17, member 2 |
SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
SUN2 | Sad1 and UNC84 domain containing 2 |
SYCE1L | synaptonemal complex central element protein 1-like |
TBC1D2 | TBC1 domain family, member 2 |
TBC1D4 | TBC1 domain family, member 4 |
TNK1 | tyrosine kinase, non-receptor, 1 |
TRAK1 | trafficking protein, kinesin binding 1 |
TRBC1 | T cell receptor beta constant 1 |
TRIB2 | tribbles pseudokinase 2 |
TRIM3 | tripartite motif containing 3 |
VAV2 | vav 2 guanine nucleotide exchange factor |
ZCCHC14 | zinc finger, CCHC domain containing 14 |
ZDHHC18 | zinc finger, DHHC-type containing 18 |
ZNF286A | zinc finger protein 286A |
ZNF34 | zinc finger protein 34 |
ZNF500 | zinc finger protein 500 |
ZNF668 | zinc finger protein 668 |
Symbol | Name |
---|---|
ABHD17B | abhydrolase domain containing 17B |
APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
ARL15 | ADP-ribosylation factor-like 15 |
ATAD2B | ATPase family, AAA domain containing 2B |
ATAD3A | ATPase family, AAA domain containing 3A |
ATP11B | ATPase, class VI, type 11B |
BEX4 | brain expressed, X-linked 4 |
BTF3P12 | basic transcription factor 3 pseudogene 12 |
C17ORF80 | chromosome 17 open reading frame 80 |
C19ORF40 | chromosome 19 open reading frame 40 |
C5 | complement component 5 |
C5ORF45 | chromosome 5 open reading frame 45 |
CCDC88C | coiled-coil domain containing 88C |
CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
CEP97 | centrosomal protein 97kDa |
CLCN2 | chloride channel, voltage-sensitive 2 |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
DMTN | dematin actin binding protein |
DNAL4 | dynein, axonemal, light chain 4 |
EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
ELOVL4 | ELOVL fatty acid elongase 4 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM114A2 | family with sequence similarity 114, member A2 |
FAM134C | family with sequence similarity 134, member C |
FRS2 | fibroblast growth factor receptor substrate 2 |
FYCO1 | FYVE and coiled-coil domain containing 1 |
GNL1 | guanine nucleotide binding protein-like 1 |
GPC3 | glypican 3 |
GPX2 | glutathione peroxidase 2 |
GRTP1 | growth hormone regulated TBC protein 1 |
GSTCD | glutathione S-transferase, C-terminal domain containing |
GSTT1 | glutathione S-transferase theta 1 |
INCENP | inner centromere protein antigens 135/155kDa |
KLF7 | Kruppel-like factor 7 (ubiquitous) |
KRI1 | KRI1 homolog (S. cerevisiae) |
L2HGDH | L-2-hydroxyglutarate dehydrogenase |
LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
LIAS | lipoic acid synthetase |
LRRC37A2 | leucine rich repeat containing 37, member A2 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
LZTR1 | leucine-zipper-like transcription regulator 1 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MFAP2 | microfibrillar-associated protein 2 |
MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
MON1B | MON1 secretory trafficking family member B |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
NHEJ1 | nonhomologous end-joining factor 1 |
NPFFR1 | neuropeptide FF receptor 1 |
NRSN2 | neurensin 2 |
OGFRL1 | opioid growth factor receptor-like 1 |
PCF11 | PCF11 cleavage and polyadenylation factor subunit |
PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
PLA2G15 | phospholipase A2, group XV |
PRICKLE3 | prickle homolog 3 (Drosophila) |
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
RNF25 | ring finger protein 25 |
RPAP1 | RNA polymerase II associated protein 1 |
RUFY2 | RUN and FYVE domain containing 2 |
SDC3 | syndecan 3 |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
SH2D4A | SH2 domain containing 4A |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
SORBS3 | sorbin and SH3 domain containing 3 |
SOX12 | SRY (sex determining region Y)-box 12 |
SP140L | SP140 nuclear body protein-like |
SPINK4 | serine peptidase inhibitor, Kazal type 4 |
SRD5A3 | steroid 5 alpha-reductase 3 |
ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
STX1A | syntaxin 1A (brain) |
SYT17 | synaptotagmin XVII |
TMEM183A | transmembrane protein 183A |
TMEM209 | transmembrane protein 209 |
TRIM5 | tripartite motif containing 5 |
TSPAN5 | tetraspanin 5 |
TWF2 | twinfilin actin binding protein 2 |
UNC119 | unc-119 homolog (C. elegans) |
VAX2 | ventral anterior homeobox 2 |
WDR60 | WD repeat domain 60 |
ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
ZDHHC24 | zinc finger, DHHC-type containing 24 |
ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
ZNF16 | zinc finger protein 16 |
ZNF205 | zinc finger protein 205 |
ZNF212 | zinc finger protein 212 |
ZNF324 | zinc finger protein 324 |
ZNF510 | zinc finger protein 510 |
ZNF557 | zinc finger protein 557 |
ZNF862 | zinc finger protein 862 |
ZSCAN31 | zinc finger and SCAN domain containing 31 |