Primary Cholangiocarcinoma Of Intrahepatic Biliary Tract Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4284013
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Genes

241 genes associated with the disease Primary Cholangiocarcinoma Of Intrahepatic Biliary Tract in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACTB actin, beta
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AFP alpha-fetoprotein
AGR3 anterior gradient 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALB albumin
APC adenomatous polyposis coli
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARID1A AT rich interactive domain 1A (SWI-like)
ARSA arylsulfatase A
ASPH aspartate beta-hydroxylase
ATF2 activating transcription factor 2
AZIN2 antizyme inhibitor 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
C17ORF97 chromosome 17 open reading frame 97
CAPNS1 calpain, small subunit 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCHCR1 coiled-coil alpha-helical rod protein 1
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD274 CD274 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD68 CD68 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHD1L chromodomain helicase DNA binding protein 1-like
CKAP4 cytoskeleton-associated protein 4
COL3A1 collagen, type III, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRP C-reactive protein, pentraxin-related
CTAG1A cancer/testis antigen 1A
CTAG1B cancer/testis antigen 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL4A cullin 4A
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DAPK1 death-associated protein kinase 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DLEC1 deleted in lung and esophageal cancer 1
DMBT1 deleted in malignant brain tumors 1
DNER delta/notch-like EGF repeat containing
DPYD dihydropyrimidine dehydrogenase
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFR epidermal growth factor receptor
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ESR2 estrogen receptor 2 (ER beta)
ESRRB estrogen-related receptor beta
EYA4 EYA transcriptional coactivator and phosphatase 4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAP fibroblast activation protein, alpha
FBLN1 fibulin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FLT4 fms-related tyrosine kinase 4
FOXM1 forkhead box M1
FSCN1 fascin actin-bundling protein 1
FTO fat mass and obesity associated
GAB1 GRB2-associated binding protein 1
GADL1 glutamate decarboxylase-like 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLP1R glucagon-like peptide 1 receptor
GLS glutaminase
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPC3 glypican 3
GRB2 growth factor receptor-bound protein 2
GSTP1 glutathione S-transferase pi 1
H2AFZ H2A histone family, member Z
HDAC1 histone deacetylase 1
HDAC8 histone deacetylase 8
HDAC9 histone deacetylase 9
HHLA2 HERV-H LTR-associating 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HOMER1 homer scaffolding protein 1
HOXB7 homeobox B7
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HSPA4 heat shock 70kDa protein 4
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPG2 heparan sulfate proteoglycan 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL1B interleukin 1, beta
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAT6A K(lysine) acetyltransferase 6A
KDR kinase insert domain receptor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT20 keratin 20, type I
L1CAM L1 cell adhesion molecule
LDHA lactate dehydrogenase A
LOXL2 lysyl oxidase-like 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRK2 leucine-rich repeat kinase 2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MECOM MDS1 and EVI1 complex locus
MFAP5 microfibrillar associated protein 5
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MUC1 mucin 1, cell surface associated
MUC13 mucin 13, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEUROG1 neurogenin 1
NF2 neurofibromin 2 (merlin)
NOTCH1 notch 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRDC nardilysin convertase
NUAK1 NUAK family, SNF1-like kinase, 1
OGG1 8-oxoguanine DNA glycosylase
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PBRM1 polybromo 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDZK1IP1 PDZK1 interacting protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKM pyruvate kinase, muscle
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPA1 pyrophosphatase (inorganic) 1
PPHLN1 periphilin 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PROM1 prominin 1
PRRT2 proline-rich transmembrane protein 2
PSG2 pregnancy specific beta-1-glycoprotein 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTEN phosphatase and tensin homolog
PTHLH parathyroid hormone-like hormone
PTK7 protein tyrosine kinase 7 (inactive)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAB1A RAB1A, member RAS oncogene family
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBP1 retinol binding protein 1, cellular
REG4 regenerating islet-derived family, member 4
RNF2 ring finger protein 2
RNF43 ring finger protein 43
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL41 ribosomal protein L41
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100A11 S100 calcium binding protein A11
S100A6 S100 calcium binding protein A6
SATB1 SATB homeobox 1
SDC1 syndecan 1
SDC2 syndecan 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SETD2 SET domain containing 2
SFRP1 secreted frizzled-related protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STYK1 serine/threonine/tyrosine kinase 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAZ tafazzin
TET1 tet methylcytosine dioxygenase 1
TFDP1 transcription factor Dp-1
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
THY1 Thy-1 cell surface antigen
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TRAF4 TNF receptor-associated factor 4
TRIM44 tripartite motif containing 44
TYMS thymidylate synthetase
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2M ubiquitin-conjugating enzyme E2M
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT3A wingless-type MMTV integration site family, member 3A
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
ZC3H12A zinc finger CCCH-type containing 12A
ZHX2 zinc fingers and homeoboxes 2