| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.17909 |
| AREG | amphiregulin | 0.141491 |
| VMP1 | vacuole membrane protein 1 | 0.0888319 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0866168 |
| RPS12 | ribosomal protein S12 | 0.0822101 |
| PCBP2 | poly(rC) binding protein 2 | 0.0763789 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.070362 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0670857 |
| KIF5B | kinesin family member 5B | 0.0664435 |
| MMP12 | matrix metallopeptidase 12 | 0.0618852 |
| RPS2 | ribosomal protein S2 | 0.0594025 |
| MKI67 | marker of proliferation Ki-67 | 0.0570103 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0567001 |
| DST | dystonin | 0.0515034 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0514229 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0510664 |
| CENPF | centromere protein F, 350/400kDa | 0.0505053 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0483187 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0474499 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0472926 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0472915 |
| PRRC2C | proline-rich coiled-coil 2C | 0.047131 |
| GOLGA4 | golgin A4 | 0.0461088 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.041932 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0403434 |
| RBM39 | RNA binding motif protein 39 | 0.0402258 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0400061 |
| SET | SET nuclear proto-oncogene | 0.0387599 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0380163 |
| RPS7 | ribosomal protein S7 | 0.037915 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0372648 |
| TMEM41B | transmembrane protein 41B | 0.0362135 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0351041 |
| DSPP | dentin sialophosphoprotein | 0.0345624 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0338158 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0335472 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0332756 |
| RPL21 | ribosomal protein L21 | 0.0331935 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0329201 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0328066 |
| ZNF638 | zinc finger protein 638 | 0.0326168 |
| ENO1 | enolase 1, (alpha) | 0.0325511 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0324924 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0323297 |
| CCDC88A | coiled-coil domain containing 88A | 0.0320106 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0319551 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0313222 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0311519 |
| PRKCI | protein kinase C, iota | 0.0307685 |
| ZNF146 | zinc finger protein 146 | 0.0306663 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305521 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0302418 |
| RPL37A | ribosomal protein L37a | 0.0300096 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0294484 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0291051 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0289852 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0288728 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0284865 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0282011 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0281233 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0280573 |
| CDK13 | cyclin-dependent kinase 13 | 0.0278733 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0277541 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0272091 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0271182 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.0266414 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0266285 |
| GOLGB1 | golgin B1 | 0.0262817 |
| QKI | QKI, KH domain containing, RNA binding | 0.0262022 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0261754 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0257925 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0257447 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0256207 |
| ZNF292 | zinc finger protein 292 | 0.0254304 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0250146 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0247095 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0246627 |
| YAP1 | Yes-associated protein 1 | 0.0245238 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0245158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0244646 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0242932 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0241992 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0241116 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0240919 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0240404 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0240271 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0238715 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0236377 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0233335 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0232481 |
| TPM3 | tropomyosin 3 | 0.0231374 |
| SSRP1 | structure specific recognition protein 1 | 0.0231306 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.023065 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0230295 |
| MSH6 | mutS homolog 6 | 0.0230195 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0230142 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0229262 |
| CENPE | centromere protein E, 312kDa | 0.0229064 |
| EHBP1 | EH domain binding protein 1 | 0.0228464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0228385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232244 |
| VIM | vimentin | -0.182368 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.134935 |
| TMSB10 | thymosin beta 10 | -0.118845 |
| SLC38A2 | solute carrier family 38, member 2 | -0.088937 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0728537 |
| RPL35A | ribosomal protein L35a | -0.0635791 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0616133 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0607416 |
| HMGA1 | high mobility group AT-hook 1 | -0.0566644 |
| MGAT4C | MGAT4 family, member C | -0.0559789 |
| NLGN1 | neuroligin 1 | -0.0542513 |
| BCHE | butyrylcholinesterase | -0.0527243 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0519835 |
| PFN1 | profilin 1 | -0.0508691 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.04895 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0474489 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0469164 |
| RPLP1 | ribosomal protein, large, P1 | -0.0468737 |
| ACTG1 | actin gamma 1 | -0.0465753 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0463178 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0461822 |
| HLA-A | major histocompatibility complex, class I, A | -0.0459963 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0457506 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0448755 |
| CCND1 | cyclin D1 | -0.0438843 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0434467 |
| RPLP0 | ribosomal protein, large, P0 | -0.0426908 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.042449 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0415495 |
| FTL | ferritin, light polypeptide | -0.0413966 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0409075 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405235 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0387611 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0387351 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380677 |
| RPS6 | ribosomal protein S6 | -0.0373028 |
| ATP11A | ATPase, class VI, type 11A | -0.0369165 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036705 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0363122 |
| H1-0 | H1.0 linker histone | -0.0360308 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0359994 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0359701 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0345186 |
| TMEM123 | transmembrane protein 123 | -0.0340142 |
| TENM3 | teneurin transmembrane protein 3 | -0.0338872 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0332014 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0329215 |
| CLDN1 | claudin 1 | -0.0325783 |
| MTAP | methylthioadenosine phosphorylase | -0.0323609 |
| POTEF | POTE ankyrin domain family, member F | -0.0321683 |
| ZNF217 | zinc finger protein 217 | -0.0315396 |
| RPS24 | ribosomal protein S24 | -0.0313792 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0313266 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0312574 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0312273 |
| S100A6 | S100 calcium binding protein A6 | -0.0311412 |
| NF1 | neurofibromin 1 | -0.0309873 |
| TXNRD1 | thioredoxin reductase 1 | -0.0297734 |
| TGM2 | transglutaminase 2 | -0.0292916 |
| CSMD1 | CUB and Sushi multiple domains 1 | -0.0291901 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0285565 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0285275 |
| RPL12 | ribosomal protein L12 | -0.0282583 |
| S100A10 | S100 calcium binding protein A10 | -0.0282087 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0276954 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0269714 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0266171 |
| CLTC | clathrin, heavy chain (Hc) | -0.0262103 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0261008 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0256632 |
| RPL27A | ribosomal protein L27a | -0.0256116 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255065 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0252746 |
| RPS19 | ribosomal protein S19 | -0.0251449 |
| RPL38 | ribosomal protein L38 | -0.0248684 |
| CDK6 | cyclin-dependent kinase 6 | -0.0246199 |
| PCDH7 | protocadherin 7 | -0.0245688 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0240239 |
| APP | amyloid beta (A4) precursor protein | -0.0239015 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0237638 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0235883 |
| CDK17 | cyclin-dependent kinase 17 | -0.0234576 |
| ZNF804A | zinc finger protein 804A | -0.0234141 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0233457 |
| CBX3 | chromobox homolog 3 | -0.0232545 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0231965 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0231651 |
| TUBB | tubulin, beta class I | -0.023084 |
| PRR16 | proline rich 16 | -0.0230701 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | -0.0230503 |
| RPL19 | ribosomal protein L19 | -0.0229454 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0228019 |
| MRPS5 | mitochondrial ribosomal protein S5 | -0.0227636 |
| VCL | vinculin | -0.0226616 |
| YBX1 | Y box binding protein 1 | -0.0226424 |
| HSPB1 | heat shock 27kDa protein 1 | -0.022017 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0215104 |
| CALR | calreticulin | -0.0214616 |
| ANXA2 | annexin A2 | -0.0213629 |
