| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0926396 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0790499 |
| MSN | moesin | 0.0770554 |
| RPS2 | ribosomal protein S2 | 0.0746678 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0647559 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0537544 |
| RPL21 | ribosomal protein L21 | 0.0509691 |
| CENPF | centromere protein F, 350/400kDa | 0.0508555 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0460861 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0410485 |
| RPS12 | ribosomal protein S12 | 0.0402932 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.039468 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0385552 |
| VMP1 | vacuole membrane protein 1 | 0.0377322 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0341364 |
| MT2A | metallothionein 2A | 0.0322676 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0316648 |
| SP3 | Sp3 transcription factor | 0.0310001 |
| GOLGA4 | golgin A4 | 0.0306602 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0298249 |
| RPS6 | ribosomal protein S6 | 0.028387 |
| RPLP2 | ribosomal protein, large, P2 | 0.0282879 |
| DSTN | destrin (actin depolymerizing factor) | 0.0270837 |
| RPS7 | ribosomal protein S7 | 0.0270584 |
| ANXA5 | annexin A5 | 0.0269603 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0267315 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0263779 |
| RPS8 | ribosomal protein S8 | 0.0262025 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0261154 |
| ARRDC3 | arrestin domain containing 3 | 0.0260868 |
| ZFP36 | ZFP36 ring finger protein | 0.0250535 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0246126 |
| SETD5 | SET domain containing 5 | 0.0245865 |
| NAV2 | neuron navigator 2 | 0.0237754 |
| TGFB2 | transforming growth factor, beta 2 | 0.023731 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0234332 |
| SET | SET nuclear proto-oncogene | 0.02338 |
| PLK2 | polo-like kinase 2 | 0.0229312 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0223719 |
| NLGN1 | neuroligin 1 | 0.0221616 |
| PNN | pinin, desmosome associated protein | 0.0219714 |
| FOSL1 | FOS-like antigen 1 | 0.0211613 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0207129 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0206467 |
| POTEF | POTE ankyrin domain family, member F | 0.0206147 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0205744 |
| RPL23 | ribosomal protein L23 | 0.0202493 |
| TPX2 | TPX2, microtubule-associated | 0.020127 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0200449 |
| MKI67 | marker of proliferation Ki-67 | 0.0200405 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0198731 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.019608 |
| RNF145 | ring finger protein 145 | 0.0195548 |
| TPM3 | tropomyosin 3 | 0.0190284 |
| LDHB | lactate dehydrogenase B | 0.0187565 |
| CENPE | centromere protein E, 312kDa | 0.0185859 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0185661 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0183742 |
| WDR43 | WD repeat domain 43 | 0.0183649 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0182356 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0180356 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0179412 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0178002 |
| PCBP2 | poly(rC) binding protein 2 | 0.0177712 |
| MFF | mitochondrial fission factor | 0.0176345 |
| H1-4 | H1.4 linker histone, cluster member | 0.0174773 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.017475 |
| CDK1 | cyclin-dependent kinase 1 | 0.0173684 |
| RNF220 | ring finger protein 220 | 0.0170253 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0168218 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0168076 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0167082 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0164567 |
| TMF1 | TATA element modulatory factor 1 | 0.0163803 |
| RPS3 | ribosomal protein S3 | 0.0159892 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0159663 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.0157791 |
| H1-2 | H1.2 linker histone, cluster member | 0.0157152 |
| RUNX1 | runt-related transcription factor 1 | 0.0156148 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0152957 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0152559 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0152308 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0151669 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.015114 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0151018 |
| RPL23A | ribosomal protein L23a | 0.0150615 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0149042 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0148393 |
| SERF2 | small EDRK-rich factor 2 | 0.0147597 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0147302 |
| KIF4A | kinesin family member 4A | 0.014691 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0146491 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0144436 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0141818 |
| TBK1 | TANK-binding kinase 1 | 0.0141359 |
| WDR26 | WD repeat domain 26 | 0.0140957 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0140805 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0139629 |
| ANLN | anillin, actin binding protein | 0.0139045 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0138834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.295495 |
| FRMD4A | FERM domain containing 4A | -0.198713 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.190867 |
| VIM | vimentin | -0.16334 |
| ASPH | aspartate beta-hydroxylase | -0.15918 |
| NDRG1 | N-myc downstream regulated 1 | -0.126231 |
| TMSB10 | thymosin beta 10 | -0.119339 |
| HLA-B | major histocompatibility complex, class I, B | -0.108069 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103673 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0976584 |
| CA12 | carbonic anhydrase XII | -0.0933928 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0930758 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0855956 |
| CP | ceruloplasmin (ferroxidase) | -0.0810014 |
| RNF213 | ring finger protein 213 | -0.0777113 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0751472 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0708919 |
| FTL | ferritin, light polypeptide | -0.0672432 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0648092 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0643823 |
| RPL35A | ribosomal protein L35a | -0.0631254 |
| CTSD | cathepsin D | -0.0577655 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0558629 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0547166 |
| MAP1B | microtubule-associated protein 1B | -0.0543875 |
| TXNRD1 | thioredoxin reductase 1 | -0.0538767 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0535173 |
| UBC | ubiquitin C | -0.053183 |
| APOL1 | apolipoprotein L, 1 | -0.0526888 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0526565 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0514947 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509001 |
| COPA | coatomer protein complex, subunit alpha | -0.0504972 |
| GLIS3 | GLIS family zinc finger 3 | -0.0498738 |
| RRBP1 | ribosome binding protein 1 | -0.0497434 |
| CAVIN1 | caveolae associated protein 1 | -0.0496225 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0493125 |
| SPAG9 | sperm associated antigen 9 | -0.0485532 |
| ARF1 | ADP-ribosylation factor 1 | -0.0474919 |
| LMNA | lamin A/C | -0.0474557 |
| PKM | pyruvate kinase, muscle | -0.0472871 |
| CALR | calreticulin | -0.0461343 |
| HLA-E | major histocompatibility complex, class I, E | -0.0450011 |
| APP | amyloid beta (A4) precursor protein | -0.0447567 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0447054 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0437422 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0435312 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0418354 |
| TPM4 | tropomyosin 4 | -0.0417721 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0410245 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0406768 |
| SP100 | SP100 nuclear antigen | -0.0394006 |
| HBP1 | HMG-box transcription factor 1 | -0.0393724 |
| HLA-C | major histocompatibility complex, class I, C | -0.0393608 |
| RPLP1 | ribosomal protein, large, P1 | -0.0392583 |
| PALLD | palladin, cytoskeletal associated protein | -0.0386985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0384369 |
| TKT | transketolase | -0.037909 |
| SDCBP | syndecan binding protein (syntenin) | -0.0372447 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0371756 |
| JUN | jun proto-oncogene | -0.0370065 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0364538 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0363927 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0360584 |
| MORF4L2 | mortality factor 4 like 2 | -0.0360364 |
| FUS | FUS RNA binding protein | -0.0359387 |
| TRAM1 | translocation associated membrane protein 1 | -0.0358133 |
| ANXA2 | annexin A2 | -0.0354826 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0352461 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0352382 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0349438 |
| TLN1 | talin 1 | -0.0342624 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.034077 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0336204 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0331119 |
| GNAS | GNAS complex locus | -0.0328662 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0327195 |
| ANXA4 | annexin A4 | -0.0326249 |
| RIGI | RNA sensor RIG-I | -0.0325868 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.032551 |
| CD44 | CD44 molecule (Indian blood group) | -0.0324726 |
| CD82 | CD82 molecule | -0.032371 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0323469 |
| RAB10 | RAB10, member RAS oncogene family | -0.0323138 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0323076 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0321388 |
| CANX | calnexin | -0.0321129 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.032023 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0319089 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0318401 |
| RPL34 | ribosomal protein L34 | -0.0317429 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0316834 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316355 |
| GLG1 | golgi glycoprotein 1 | -0.0315741 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0313988 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0311646 |
| PXDN | peroxidasin | -0.0309876 |
| RPL19 | ribosomal protein L19 | -0.0309647 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308262 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0307708 |
