| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.154208 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0665286 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0586823 |
| MSN | moesin | 0.0537829 |
| ZFP36 | ZFP36 ring finger protein | 0.043132 |
| RPL21 | ribosomal protein L21 | 0.0399345 |
| MT2A | metallothionein 2A | 0.0387328 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352387 |
| FOSL1 | FOS-like antigen 1 | 0.0337332 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0326014 |
| RPS2 | ribosomal protein S2 | 0.0303439 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0297266 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0283198 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.027983 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0262417 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0247931 |
| RTN4 | reticulon 4 | 0.0244582 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0234733 |
| TBK1 | TANK-binding kinase 1 | 0.0232992 |
| RPS7 | ribosomal protein S7 | 0.0229272 |
| RPS12 | ribosomal protein S12 | 0.0225581 |
| GOLGA4 | golgin A4 | 0.0224861 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0224207 |
| SETD5 | SET domain containing 5 | 0.0220927 |
| WDR43 | WD repeat domain 43 | 0.0218838 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0210309 |
| HDGF | hepatoma-derived growth factor | 0.020493 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204257 |
| CLU | clusterin | 0.0202586 |
| RNF145 | ring finger protein 145 | 0.0200821 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0199084 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0198189 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0195854 |
| TMF1 | TATA element modulatory factor 1 | 0.0195612 |
| TMEM165 | transmembrane protein 165 | 0.0194777 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0191918 |
| ANXA5 | annexin A5 | 0.0190594 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0190327 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0187337 |
| VMP1 | vacuole membrane protein 1 | 0.0186342 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0185114 |
| SCFD1 | sec1 family domain containing 1 | 0.0183918 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0182836 |
| FAM13A | family with sequence similarity 13, member A | 0.0180609 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0180076 |
| SSRP1 | structure specific recognition protein 1 | 0.0178404 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0176563 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0170012 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0169453 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0167145 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0165521 |
| PNN | pinin, desmosome associated protein | 0.0164533 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0162473 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.016104 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0160041 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0159353 |
| STC1 | stanniocalcin 1 | 0.0157315 |
| CCNL1 | cyclin L1 | 0.0155921 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0154676 |
| ZNF292 | zinc finger protein 292 | 0.0151747 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0150787 |
| H1-2 | H1.2 linker histone, cluster member | 0.0149755 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0149468 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.014852 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0148444 |
| SRP54 | signal recognition particle 54kDa | 0.0148052 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0147953 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0146188 |
| TMEM87A | transmembrane protein 87A | 0.0143238 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0142605 |
| DENR | density-regulated protein | 0.0141686 |
| PDCD5 | programmed cell death 5 | 0.0133428 |
| SET | SET nuclear proto-oncogene | 0.0133194 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0132728 |
| ARFGEF3 | ARFGEF family member 3 | 0.0131934 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0129444 |
| TOP1 | topoisomerase (DNA) I | 0.0128443 |
| VIRMA | vir like m6A methyltransferase associated | 0.0128318 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0127627 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0127015 |
| NUP153 | nucleoporin 153kDa | 0.0126159 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0126123 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0125763 |
| TMEM41B | transmembrane protein 41B | 0.0125736 |
| AUTS2 | autism susceptibility candidate 2 | 0.0125001 |
| MFF | mitochondrial fission factor | 0.0124063 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0122963 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0122363 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0121837 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0121012 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0120712 |
| SP3 | Sp3 transcription factor | 0.0120686 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0120224 |
| THUMPD2 | THUMP domain containing 2 | 0.0119574 |
| MTSS1 | metastasis suppressor 1 | 0.0119338 |
| CDC27 | cell division cycle 27 | 0.011927 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0119183 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0119168 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0118773 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0118649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217084 |
| ACTG1 | actin gamma 1 | -0.201202 |
| FTL | ferritin, light polypeptide | -0.169599 |
| TMSB10 | thymosin beta 10 | -0.150078 |
| ANXA2 | annexin A2 | -0.138232 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.117764 |
| RPLP1 | ribosomal protein, large, P1 | -0.0989426 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0986399 |
| VIM | vimentin | -0.0981612 |
| KYNU | kynureninase | -0.0811515 |
| UBC | ubiquitin C | -0.0772571 |
| PDE10A | phosphodiesterase 10A | -0.0767337 |
| ACTN4 | actinin, alpha 4 | -0.0711933 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0705536 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0699895 |
| ASPH | aspartate beta-hydroxylase | -0.069772 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0688325 |
| RNF213 | ring finger protein 213 | -0.06816 |
| PTMA | prothymosin, alpha | -0.0666476 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0666258 |
| AHNAK | AHNAK nucleoprotein | -0.0662815 |
| TXNRD1 | thioredoxin reductase 1 | -0.0662055 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0661071 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0646454 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0633006 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0630657 |
| TKT | transketolase | -0.0630362 |
| PKM | pyruvate kinase, muscle | -0.0626586 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0623419 |
| RPS24 | ribosomal protein S24 | -0.0617628 |
| FNDC3B | fibronectin type III domain containing 3B | -0.059201 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0581219 |
| OSMR | oncostatin M receptor | -0.0579527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0566014 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0552213 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0550009 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0540889 |
| EFNA5 | ephrin-A5 | -0.0520795 |
| NDRG1 | N-myc downstream regulated 1 | -0.0514929 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0501386 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0489913 |
| SMAD3 | SMAD family member 3 | -0.0482985 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0469515 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0465393 |
| S100A6 | S100 calcium binding protein A6 | -0.0461541 |
| LDHA | lactate dehydrogenase A | -0.0460158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0450916 |
| EHBP1 | EH domain binding protein 1 | -0.0446782 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0444157 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0443389 |
| RPL4 | ribosomal protein L4 | -0.0441349 |
| RPS16 | ribosomal protein S16 | -0.0424417 |
| PGK1 | phosphoglycerate kinase 1 | -0.0423186 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0421654 |
| CA12 | carbonic anhydrase XII | -0.0413596 |
| RPL35A | ribosomal protein L35a | -0.041113 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0408651 |
| PARD3 | par-3 family cell polarity regulator | -0.0407067 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0406571 |
| FLNA | filamin A, alpha | -0.0405381 |
| APP | amyloid beta (A4) precursor protein | -0.0402932 |
| RPS27A | ribosomal protein S27a | -0.0398922 |
| S100A10 | S100 calcium binding protein A10 | -0.0395688 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0394828 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0390787 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0384978 |
| RPL12 | ribosomal protein L12 | -0.0381758 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0381668 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.037792 |
| CANX | calnexin | -0.0377741 |
| RPS5 | ribosomal protein S5 | -0.0376908 |
| TNS3 | tensin 3 | -0.0375297 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0375142 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0374062 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0372098 |
| KRT7 | keratin 7, type II | -0.0368704 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365737 |
| RPL8 | ribosomal protein L8 | -0.0363623 |
| RPL26 | ribosomal protein L26 | -0.0362743 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0362145 |
| TMSB4X | thymosin beta 4, X-linked | -0.035944 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0356708 |
| PLEC | plectin | -0.0353992 |
| RPL28 | ribosomal protein L28 | -0.0353091 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0341253 |
| KRT18 | keratin 18, type I | -0.033619 |
| GLIS3 | GLIS family zinc finger 3 | -0.0327653 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0321938 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0320796 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0320278 |
| MORF4L2 | mortality factor 4 like 2 | -0.032023 |
| HDLBP | high density lipoprotein binding protein | -0.0320041 |
| ZNF207 | zinc finger protein 207 | -0.0319774 |
| RPS4X | ribosomal protein S4, X-linked | -0.0314234 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0311403 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0309711 |
| RAB10 | RAB10, member RAS oncogene family | -0.0308156 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0306026 |
| SMAD2 | SMAD family member 2 | -0.0301511 |
| USP3 | ubiquitin specific peptidase 3 | -0.02977 |
