| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0951691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0849867 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0804433 |
| MT2A | metallothionein 2A | 0.0803587 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0698691 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0650279 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0644581 |
| ASPH | aspartate beta-hydroxylase | 0.0609494 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0514894 |
| FOSL1 | FOS-like antigen 1 | 0.045774 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0430779 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0412216 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0392423 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0384703 |
| RPS12 | ribosomal protein S12 | 0.0383493 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.037557 |
| RNF145 | ring finger protein 145 | 0.0372999 |
| RFX7 | regulatory factor X, 7 | 0.0347993 |
| SETD5 | SET domain containing 5 | 0.0343274 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.033914 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0333236 |
| FAM117B | family with sequence similarity 117, member B | 0.0322961 |
| ZFP36 | ZFP36 ring finger protein | 0.0309775 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0308432 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0299781 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0293265 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0292709 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0291976 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0279792 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0274996 |
| RNF150 | ring finger protein 150 | 0.0270009 |
| VEGFA | vascular endothelial growth factor A | 0.0269521 |
| RPL21 | ribosomal protein L21 | 0.0268595 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267881 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0265241 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0261956 |
| NUP58 | nucleoporin 58 | 0.0258181 |
| PLIN2 | perilipin 2 | 0.025601 |
| RPS6 | ribosomal protein S6 | 0.0254682 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0253886 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0250994 |
| MSN | moesin | 0.0249132 |
| ZNF292 | zinc finger protein 292 | 0.0246147 |
| RPS2 | ribosomal protein S2 | 0.0244653 |
| PRELID2 | PRELI domain containing 2 | 0.0241594 |
| TBK1 | TANK-binding kinase 1 | 0.0239128 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.02308 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0223956 |
| CD109 | CD109 molecule | 0.0221232 |
| PCBP2 | poly(rC) binding protein 2 | 0.0219939 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0219278 |
| ANXA5 | annexin A5 | 0.0212349 |
| ZNF638 | zinc finger protein 638 | 0.0212034 |
| LNPK | lunapark, ER junction formation factor | 0.0211847 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0209783 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0208396 |
| CENPF | centromere protein F, 350/400kDa | 0.0207236 |
| RPL37A | ribosomal protein L37a | 0.0203895 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0200316 |
| ARRDC3 | arrestin domain containing 3 | 0.0192912 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0192318 |
| TMF1 | TATA element modulatory factor 1 | 0.0191566 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0191239 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.019004 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0186873 |
| IL6ST | interleukin 6 signal transducer | 0.0183882 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0180323 |
| VMP1 | vacuole membrane protein 1 | 0.018015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0178749 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0176773 |
| SUCO | SUN domain containing ossification factor | 0.017662 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0174697 |
| ENO1 | enolase 1, (alpha) | 0.0174067 |
| RNF24 | ring finger protein 24 | 0.0172498 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0171765 |
| FRMD6 | FERM domain containing 6 | 0.0171109 |
| DSTN | destrin (actin depolymerizing factor) | 0.0170124 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0170032 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0169205 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.01686 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0168362 |
| TPM3 | tropomyosin 3 | 0.0166556 |
| PHF21A | PHD finger protein 21A | 0.0166381 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0165244 |
| SET | SET nuclear proto-oncogene | 0.0163206 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0162988 |
| MKI67 | marker of proliferation Ki-67 | 0.0162636 |
| YEATS2 | YEATS domain containing 2 | 0.0157193 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0156401 |
| NGLY1 | N-glycanase 1 | 0.0154977 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0152977 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0152718 |
| MKRN1 | makorin ring finger protein 1 | 0.0151963 |
| RPL11 | ribosomal protein L11 | 0.0151915 |
| SPICE1 | spindle and centriole associated protein 1 | 0.0150853 |
| CCNL1 | cyclin L1 | 0.015065 |
| CDK19 | cyclin-dependent kinase 19 | 0.0150494 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0149179 |
| TXNIP | thioredoxin interacting protein | 0.0149051 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0148256 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.359047 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.231892 |
| VGF | VGF nerve growth factor inducible | -0.174992 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167638 |
| FMN1 | formin 1 | -0.132023 |
| VIM | vimentin | -0.105859 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.101074 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.093209 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0800839 |
| GDF15 | growth differentiation factor 15 | -0.0759713 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0753578 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0692898 |
| EGR1 | early growth response 1 | -0.0679699 |
| ACTG1 | actin gamma 1 | -0.0675597 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0675563 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0662492 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0645542 |
| PTCHD4 | patched domain containing 4 | -0.0606394 |
| NPR2 | natriuretic peptide receptor 2 | -0.0585188 |
| HMCN1 | hemicentin 1 | -0.0584007 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0569033 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0534668 |
| TNNC1 | troponin C type 1 (slow) | -0.0524586 |
| VCL | vinculin | -0.050695 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0506194 |
| HBP1 | HMG-box transcription factor 1 | -0.0505818 |
| CALU | calumenin | -0.0501055 |
| PGK1 | phosphoglycerate kinase 1 | -0.0478018 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0470895 |
| APP | amyloid beta (A4) precursor protein | -0.0465936 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0464517 |
| CALR | calreticulin | -0.0459646 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.045353 |
| FUS | FUS RNA binding protein | -0.0451505 |
| AHNAK | AHNAK nucleoprotein | -0.0448326 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0426134 |
| TMEM123 | transmembrane protein 123 | -0.0423916 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.040901 |
| RHEB | Ras homolog enriched in brain | -0.0405148 |
| PAX3 | paired box 3 | -0.0401655 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0400498 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0389819 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0389392 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.038331 |
| DENND1A | DENN/MADD domain containing 1A | -0.0382902 |
| CANX | calnexin | -0.0381562 |
| A2M | alpha-2-macroglobulin | -0.0380027 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0378881 |
| ANXA2 | annexin A2 | -0.037606 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0370886 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0369808 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0367914 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0367084 |
| ATF6 | activating transcription factor 6 | -0.0362886 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.035056 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0343446 |
| ACTN1 | actinin, alpha 1 | -0.0339041 |
| IER3 | immediate early response 3 | -0.0338224 |
| SFTPA2 | surfactant protein A2 | -0.0335892 |
| SPAG9 | sperm associated antigen 9 | -0.033497 |
| NAV3 | neuron navigator 3 | -0.0331424 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0328505 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0328389 |
| JUN | jun proto-oncogene | -0.0327449 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327173 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0325568 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0315199 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0314067 |
| RLF | rearranged L-myc fusion | -0.0312131 |
| CUX1 | cut-like homeobox 1 | -0.0309452 |
| TLE4 | transducin-like enhancer of split 4 | -0.0308209 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.03079 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0307366 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0307109 |
| CUL1 | cullin 1 | -0.0305246 |
| EMP1 | epithelial membrane protein 1 | -0.0303354 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0300779 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0299797 |
| SDC2 | syndecan 2 | -0.0297753 |
| FRMD5 | FERM domain containing 5 | -0.0297055 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0294902 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0290788 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0290111 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0287028 |
| SDCBP | syndecan binding protein (syntenin) | -0.0284093 |
| TMSB10 | thymosin beta 10 | -0.0283748 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0281233 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0280079 |
| ACTN4 | actinin, alpha 4 | -0.0279139 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0278319 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0275353 |
| HELZ | helicase with zinc finger | -0.0274596 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0271753 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0271732 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.026842 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0267977 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0267645 |
| MTPN | myotrophin | -0.0267184 |
| LRRC23 | leucine rich repeat containing 23 | -0.0259523 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0257861 |
