| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127173 |
| MT2A | metallothionein 2A | 0.121151 |
| B2M | beta-2-microglobulin | 0.118126 |
| PTMA | prothymosin, alpha | 0.11171 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10253 |
| POTEF | POTE ankyrin domain family, member F | 0.101672 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0984242 |
| LAMB3 | laminin, beta 3 | 0.0947366 |
| ENO1 | enolase 1, (alpha) | 0.091695 |
| KRT19 | keratin 19, type I | 0.0907554 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0847337 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.08402 |
| NDRG1 | N-myc downstream regulated 1 | 0.0749204 |
| S100A6 | S100 calcium binding protein A6 | 0.074507 |
| FAM13A | family with sequence similarity 13, member A | 0.0720972 |
| MMP7 | matrix metallopeptidase 7 | 0.0702426 |
| TMSB10 | thymosin beta 10 | 0.0701716 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0685688 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0634934 |
| FOSL1 | FOS-like antigen 1 | 0.0601153 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0572504 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0546966 |
| APOL1 | apolipoprotein L, 1 | 0.0544175 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.054357 |
| VEGFA | vascular endothelial growth factor A | 0.0511276 |
| RPS8 | ribosomal protein S8 | 0.0495753 |
| PLAT | plasminogen activator, tissue | 0.0491751 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0485789 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0472845 |
| HMGA1 | high mobility group AT-hook 1 | 0.0460112 |
| RPL23 | ribosomal protein L23 | 0.045465 |
| MEF2A | myocyte enhancer factor 2A | 0.044998 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0445738 |
| TXNIP | thioredoxin interacting protein | 0.0444736 |
| MCL1 | myeloid cell leukemia 1 | 0.0442483 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0437536 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0436456 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0434957 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0428938 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0423812 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0423571 |
| VIM | vimentin | 0.0420593 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.041878 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.041716 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0408955 |
| S100A10 | S100 calcium binding protein A10 | 0.0406137 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0397934 |
| RIOK3 | RIO kinase 3 | 0.0396734 |
| CSTB | cystatin B (stefin B) | 0.0392092 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0389661 |
| FLNB | filamin B, beta | 0.0389353 |
| ITGA6 | integrin, alpha 6 | 0.0389138 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0386529 |
| ASPH | aspartate beta-hydroxylase | 0.0386169 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0385453 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0368574 |
| LAMA4 | laminin, alpha 4 | 0.0366853 |
| TAGLN2 | transgelin 2 | 0.0361683 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0361386 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0357622 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0356372 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0355029 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0354831 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.035479 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0352887 |
| CCNY | cyclin Y | 0.0345526 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0345462 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0344609 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.033512 |
| RPS19 | ribosomal protein S19 | 0.0332594 |
| RPS6 | ribosomal protein S6 | 0.03308 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328376 |
| FAM162A | family with sequence similarity 162, member A | 0.0326543 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0324115 |
| EZR | ezrin | 0.0323219 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316791 |
| PCBP2 | poly(rC) binding protein 2 | 0.031665 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0316074 |
| LMNA | lamin A/C | 0.0315988 |
| LCN2 | lipocalin 2 | 0.0315155 |
| CD47 | CD47 molecule | 0.0314907 |
| JUP | junction plakoglobin | 0.031488 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0313037 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0308917 |
| MSN | moesin | 0.0308202 |
| FTL | ferritin, light polypeptide | 0.0307385 |
| TPM4 | tropomyosin 4 | 0.0305744 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0300449 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0299736 |
| S100A11 | S100 calcium binding protein A11 | 0.0296174 |
| MYADM | myeloid-associated differentiation marker | 0.0295084 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0292003 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0290465 |
| RPL37A | ribosomal protein L37a | 0.0288798 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0285602 |
| ACTG1 | actin gamma 1 | 0.0284508 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.028372 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0282382 |
| RPS12 | ribosomal protein S12 | 0.0282081 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0280224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102509 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0803603 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0777821 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0522169 |
| APP | amyloid beta (A4) precursor protein | -0.0509309 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0485495 |
| PHF3 | PHD finger protein 3 | -0.0481246 |
| BICC1 | BicC family RNA binding protein 1 | -0.0455552 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0454335 |
| NABP1 | nucleic acid binding protein 1 | -0.0426839 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0419206 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0409897 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0403065 |
| MYO1E | myosin IE | -0.0394743 |
| RUNX1 | runt-related transcription factor 1 | -0.0376848 |
| AHNAK | AHNAK nucleoprotein | -0.0373502 |
| ANXA2 | annexin A2 | -0.037219 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0370442 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0361977 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0361743 |
| SYNRG | synergin, gamma | -0.0358364 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0339189 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0338772 |
| HLA-C | major histocompatibility complex, class I, C | -0.0338283 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0335709 |
| MUC4 | mucin 4, cell surface associated | -0.0333991 |
| INTS6 | integrator complex subunit 6 | -0.0329365 |
| TJP1 | tight junction protein 1 | -0.0328196 |
| AFF4 | AF4/FMR2 family, member 4 | -0.032788 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.032675 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0323526 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0319605 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0318498 |
| DST | dystonin | -0.0317939 |
| FNIP1 | folliculin interacting protein 1 | -0.0316435 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0312247 |
| LMO7 | LIM domain 7 | -0.0308088 |
| MYOF | myoferlin | -0.0305772 |
| SP100 | SP100 nuclear antigen | -0.0304074 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0294608 |
| OSMR | oncostatin M receptor | -0.0293483 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0285197 |
| HDLBP | high density lipoprotein binding protein | -0.0282579 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0279247 |
| CANX | calnexin | -0.0278806 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0276857 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0270329 |
| EFNA5 | ephrin-A5 | -0.0268493 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0266553 |
| RNF213 | ring finger protein 213 | -0.0266452 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0265489 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.026162 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0259917 |
| RBM47 | RNA binding motif protein 47 | -0.025484 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0253059 |
| CLTC | clathrin, heavy chain (Hc) | -0.0250857 |
| KYNU | kynureninase | -0.0243482 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0242638 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0241514 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0241231 |
| VCL | vinculin | -0.0235036 |
| HKDC1 | hexokinase domain containing 1 | -0.02349 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0234526 |
| SPAG9 | sperm associated antigen 9 | -0.0233165 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0228474 |
| PRKCA | protein kinase C, alpha | -0.0223364 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0220181 |
| USP53 | ubiquitin specific peptidase 53 | -0.0219309 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.021865 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0216705 |
| RPL4 | ribosomal protein L4 | -0.0216555 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0214897 |
| NTN4 | netrin 4 | -0.021475 |
| ARF1 | ADP-ribosylation factor 1 | -0.0214639 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.021231 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.021072 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0210496 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0206204 |
| MUC16 | mucin 16, cell surface associated | -0.0205829 |
| GPHN | gephyrin | -0.020554 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.020371 |
| NRP1 | neuropilin 1 | -0.0203546 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0202816 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0202736 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0199215 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.019916 |
| MCU | mitochondrial calcium uniporter | -0.0198339 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0197614 |
| CDK12 | cyclin-dependent kinase 12 | -0.0196675 |
| PLEC | plectin | -0.0196266 |
| PCNX4 | pecanex 4 | -0.0194667 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0194416 |
| FUS | FUS RNA binding protein | -0.0193987 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.019383 |
| TBC1D22A | TBC1 domain family, member 22A | -0.019355 |
| SMYD3 | SET and MYND domain containing 3 | -0.0192725 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.019237 |
| EPAS1 | endothelial PAS domain protein 1 | -0.01919 |
| NRG3 | neuregulin 3 | -0.0190605 |
| RTN3 | reticulon 3 | -0.0187527 |
