| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.107501 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0911063 |
| NRG1 | neuregulin 1 | 0.0718501 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0718004 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0708052 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0630457 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0590105 |
| RPS12 | ribosomal protein S12 | 0.057629 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0571081 |
| RPS6 | ribosomal protein S6 | 0.0568313 |
| DPH6 | diphthamine biosynthesis 6 | 0.049977 |
| VMP1 | vacuole membrane protein 1 | 0.0493245 |
| RPL37A | ribosomal protein L37a | 0.0412286 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0398068 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0393363 |
| SET | SET nuclear proto-oncogene | 0.0393307 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0391015 |
| RPL21 | ribosomal protein L21 | 0.0384582 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0378392 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0374147 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0372034 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0368342 |
| REST | RE1-silencing transcription factor | 0.0365897 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0353008 |
| CENPF | centromere protein F, 350/400kDa | 0.0349337 |
| RPS2 | ribosomal protein S2 | 0.034931 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.034627 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.033594 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0319615 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0316557 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0313134 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0307033 |
| ZFP36 | ZFP36 ring finger protein | 0.0304271 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0303695 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0301958 |
| MKI67 | marker of proliferation Ki-67 | 0.02926 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0290973 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0283758 |
| VEGFA | vascular endothelial growth factor A | 0.02833 |
| EFNA5 | ephrin-A5 | 0.0278889 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0276388 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0274175 |
| CRH | corticotropin releasing hormone | 0.0271549 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0268942 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0267987 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264412 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0259868 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0258472 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0257609 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0255888 |
| PHF3 | PHD finger protein 3 | 0.0252463 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0247917 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0246791 |
| HDAC8 | histone deacetylase 8 | 0.0246054 |
| CLIC4 | chloride intracellular channel 4 | 0.0245448 |
| RPL36A | ribosomal protein L36a | 0.024419 |
| TPM3 | tropomyosin 3 | 0.023868 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0238053 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.023515 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0233984 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0233255 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0233056 |
| FN1 | fibronectin 1 | 0.0232607 |
| TCF12 | transcription factor 12 | 0.0231914 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0230758 |
| SETD5 | SET domain containing 5 | 0.0230374 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0228627 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.022526 |
| CEP112 | centrosomal protein 112kDa | 0.0225132 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0224997 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0223731 |
| SETD2 | SET domain containing 2 | 0.022259 |
| SPAG16 | sperm associated antigen 16 | 0.022064 |
| RAD51B | RAD51 paralog B | 0.0219689 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.021922 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0219072 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0219028 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0217911 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0217785 |
| THOC2 | THO complex 2 | 0.0217765 |
| CDH13 | cadherin 13 | 0.0216607 |
| PHOX2B | paired-like homeobox 2b | 0.0216157 |
| DIAPH2 | diaphanous-related formin 2 | 0.0215176 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.021411 |
| NREP | neuronal regeneration related protein | 0.0213192 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0213186 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0211869 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0211859 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0211494 |
| MEF2A | myocyte enhancer factor 2A | 0.0210692 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0210363 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0208714 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0208603 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0208543 |
| RSF1 | remodeling and spacing factor 1 | 0.0207816 |
| STC1 | stanniocalcin 1 | 0.0207197 |
| EGFR | epidermal growth factor receptor | 0.0206255 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0206088 |
| LAMB1 | laminin, beta 1 | 0.0204462 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0203381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.354968 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.264948 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137284 |
| VIM | vimentin | -0.112062 |
| WDR45B | WD repeat domain 45B | -0.0936899 |
| SYT1 | synaptotagmin I | -0.0735217 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0668252 |
| OGA | O-GlcNAcase | -0.0616713 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0605755 |
| VCL | vinculin | -0.0604717 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0597813 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0576931 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0556023 |
| MED13 | mediator complex subunit 13 | -0.0546761 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0537751 |
| COL3A1 | collagen, type III, alpha 1 | -0.0512341 |
| TMSB10 | thymosin beta 10 | -0.051215 |
| FMN1 | formin 1 | -0.0491075 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0484342 |
| ANXA2 | annexin A2 | -0.0477926 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0471167 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0463982 |
| CLTC | clathrin, heavy chain (Hc) | -0.0460682 |
| SPAG9 | sperm associated antigen 9 | -0.0440157 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0439669 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0435752 |
| NDRG1 | N-myc downstream regulated 1 | -0.0434288 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0421815 |
| APP | amyloid beta (A4) precursor protein | -0.0412065 |
| RPLP1 | ribosomal protein, large, P1 | -0.0409798 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.039917 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0388473 |
| BSG | basigin (Ok blood group) | -0.0387398 |
| GNAS | GNAS complex locus | -0.0382812 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0382284 |
| AUTS2 | autism susceptibility candidate 2 | -0.0379454 |
| RPL35A | ribosomal protein L35a | -0.0378161 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0376886 |
| RNF213 | ring finger protein 213 | -0.0368058 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0367614 |
| ARF1 | ADP-ribosylation factor 1 | -0.0364387 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0361458 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0358817 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0354247 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0354122 |
| TRIB2 | tribbles pseudokinase 2 | -0.0353315 |
| LMNA | lamin A/C | -0.03508 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0343158 |
| HELZ | helicase with zinc finger | -0.0340453 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.033834 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0335952 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335404 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0334307 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0332174 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0332067 |
| CDC27 | cell division cycle 27 | -0.0331819 |
| CABIN1 | calcineurin binding protein 1 | -0.032451 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0324028 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0320609 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0316627 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0314911 |
| MMP2 | matrix metallopeptidase 2 | -0.0312251 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0311673 |
| RAB30 | RAB30, member RAS oncogene family | -0.0310876 |
| TOP1 | topoisomerase (DNA) I | -0.0310492 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0308022 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0306745 |
| LPIN1 | lipin 1 | -0.0305547 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0303511 |
| PTGES2 | prostaglandin E synthase 2 | -0.0299965 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0299856 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0298922 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.029748 |
| AHNAK | AHNAK nucleoprotein | -0.0296629 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0295769 |
| ACTG1 | actin gamma 1 | -0.029394 |
| GOLGB1 | golgin B1 | -0.0292961 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0292572 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0290727 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0286417 |
| POTEF | POTE ankyrin domain family, member F | -0.0285214 |
| GDF15 | growth differentiation factor 15 | -0.028487 |
| CSNK1G1 | casein kinase 1, gamma 1 | -0.0283178 |
| RBM20 | RNA binding motif protein 20 | -0.0282296 |
| SEC24D | SEC24 family member D | -0.0281694 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0279125 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0278648 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.027844 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0277053 |
| S100A6 | S100 calcium binding protein A6 | -0.0276945 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0275841 |
| MBTD1 | mbt domain containing 1 | -0.0273808 |
| PHIP | pleckstrin homology domain interacting protein | -0.0270546 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270477 |
| CADM1 | cell adhesion molecule 1 | -0.0270321 |
| RFX7 | regulatory factor X, 7 | -0.0270187 |
| USP36 | ubiquitin specific peptidase 36 | -0.026864 |
| RPL4 | ribosomal protein L4 | -0.026681 |
| MAP1B | microtubule-associated protein 1B | -0.0264286 |
