| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0937768 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0886945 |
| FAM13A | family with sequence similarity 13, member A | 0.0697398 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0648124 |
| EGFR | epidermal growth factor receptor | 0.048645 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0461536 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.044721 |
| GOLGA4 | golgin A4 | 0.0373626 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0359251 |
| RPS2 | ribosomal protein S2 | 0.0350834 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0315812 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0297311 |
| CADM1 | cell adhesion molecule 1 | 0.0283717 |
| SRP54 | signal recognition particle 54kDa | 0.0279905 |
| MMP12 | matrix metallopeptidase 12 | 0.0277811 |
| SET | SET nuclear proto-oncogene | 0.0275223 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0264867 |
| SEC24A | SEC24 family member A | 0.0262419 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0254572 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0248114 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0247847 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247614 |
| SETD5 | SET domain containing 5 | 0.0229468 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0226626 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0223147 |
| PLIN2 | perilipin 2 | 0.0214519 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0211427 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0209365 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0207833 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0205064 |
| MSN | moesin | 0.0204088 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0203583 |
| HELZ | helicase with zinc finger | 0.0202872 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0201363 |
| RPS12 | ribosomal protein S12 | 0.0198889 |
| ADM | adrenomedullin | 0.0191364 |
| NUP58 | nucleoporin 58 | 0.0189057 |
| INSIG2 | insulin induced gene 2 | 0.0186574 |
| TMF1 | TATA element modulatory factor 1 | 0.0184043 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0179732 |
| ANXA5 | annexin A5 | 0.0177293 |
| ZNF395 | zinc finger protein 395 | 0.017442 |
| RACK1 | receptor for activated C kinase 1 | 0.0174126 |
| RPL21 | ribosomal protein L21 | 0.0170897 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0170394 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0168907 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0163482 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0163424 |
| TPM3 | tropomyosin 3 | 0.0163422 |
| STC1 | stanniocalcin 1 | 0.01606 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0158899 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0153799 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0153679 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.015257 |
| USP3 | ubiquitin specific peptidase 3 | 0.0152314 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0152138 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0151052 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0148746 |
| MTDH | metadherin | 0.0144435 |
| RLF | rearranged L-myc fusion | 0.0142816 |
| CSTB | cystatin B (stefin B) | 0.0142803 |
| SPAG9 | sperm associated antigen 9 | 0.0141753 |
| SUCO | SUN domain containing ossification factor | 0.0141363 |
| HDGF | hepatoma-derived growth factor | 0.0137036 |
| FSCN1 | fascin actin-bundling protein 1 | 0.013646 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0135544 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0134731 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0134134 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0133788 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0133057 |
| SEPTIN2 | septin 2 | 0.0131643 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0131135 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0130558 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0129889 |
| SBF2 | SET binding factor 2 | 0.0129417 |
| WDR45B | WD repeat domain 45B | 0.0129115 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0127725 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0127218 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0125995 |
| RPS8 | ribosomal protein S8 | 0.0125988 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0125882 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0125193 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0124587 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0124572 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0123587 |
| CD109 | CD109 molecule | 0.012357 |
| RAI1 | retinoic acid induced 1 | 0.0123229 |
| LAMB1 | laminin, beta 1 | 0.012322 |
| CCDC14 | coiled-coil domain containing 14 | 0.0121127 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0121114 |
| RAB7A | RAB7A, member RAS oncogene family | 0.012079 |
| QKI | QKI, KH domain containing, RNA binding | 0.0120189 |
| WDR43 | WD repeat domain 43 | 0.0119827 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0119663 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0119619 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0118526 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0115458 |
| RNF145 | ring finger protein 145 | 0.0114555 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0113408 |
| RPS6 | ribosomal protein S6 | 0.0113002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169341 |
| MT2A | metallothionein 2A | -0.10507 |
| FTL | ferritin, light polypeptide | -0.103619 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0804829 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0726531 |
| ASPH | aspartate beta-hydroxylase | -0.0678811 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0646455 |
| TMSB10 | thymosin beta 10 | -0.0598319 |
| CD44 | CD44 molecule (Indian blood group) | -0.0565695 |
| VIM | vimentin | -0.0547925 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0500842 |
| HLA-B | major histocompatibility complex, class I, B | -0.0482175 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0474688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469595 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460451 |
| TXNRD1 | thioredoxin reductase 1 | -0.0456041 |
| NLGN1 | neuroligin 1 | -0.0425885 |
| OSMR | oncostatin M receptor | -0.0420945 |
| ATXN1 | ataxin 1 | -0.0417969 |
| GLIS3 | GLIS family zinc finger 3 | -0.0403395 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0387681 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378203 |
| MAP1B | microtubule-associated protein 1B | -0.035734 |
| EXT1 | exostosin glycosyltransferase 1 | -0.035729 |
| FN1 | fibronectin 1 | -0.0344324 |
| RPL35A | ribosomal protein L35a | -0.0343154 |
| RPL28 | ribosomal protein L28 | -0.0326225 |
| KYNU | kynureninase | -0.0321658 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0320172 |
| MT1X | metallothionein 1X | -0.0313198 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0304046 |
| EGR1 | early growth response 1 | -0.0301892 |
| VCL | vinculin | -0.0296765 |
| ACTN4 | actinin, alpha 4 | -0.0292712 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0279976 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0276544 |
| RPL34 | ribosomal protein L34 | -0.0262017 |
| RUNX1 | runt-related transcription factor 1 | -0.0260797 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259354 |
| RPS19 | ribosomal protein S19 | -0.0258845 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0257439 |
| CALN1 | calneuron 1 | -0.0248294 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.02437 |
| PTK2 | protein tyrosine kinase 2 | -0.0242706 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0241375 |
| PHF14 | PHD finger protein 14 | -0.0240165 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0237829 |
| NAV2 | neuron navigator 2 | -0.0232496 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0227892 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0226845 |
| SMYD3 | SET and MYND domain containing 3 | -0.0226342 |
| NF1 | neurofibromin 1 | -0.0226052 |
| RPS13 | ribosomal protein S13 | -0.0222469 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0222398 |
| TNNC1 | troponin C type 1 (slow) | -0.0221233 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0218536 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.021738 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.021529 |
| AHR | aryl hydrocarbon receptor | -0.0213039 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0212025 |
| RNF216 | ring finger protein 216 | -0.0211683 |
| NAV1 | neuron navigator 1 | -0.0210518 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0205537 |
| AHNAK | AHNAK nucleoprotein | -0.0204112 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0203186 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0202648 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0202401 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0202348 |
| CDK14 | cyclin-dependent kinase 14 | -0.020012 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0199439 |
| PKM | pyruvate kinase, muscle | -0.0199073 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0189571 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0189234 |
| EXOC6B | exocyst complex component 6B | -0.0188096 |
| STK17A | serine/threonine kinase 17a | -0.0182265 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0181614 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.018109 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0180703 |
| RNF213 | ring finger protein 213 | -0.0180419 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0179728 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0177082 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0175341 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0174323 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0171362 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0170093 |
| METTL15 | methyltransferase like 15 | -0.0169295 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0167927 |
| WWOX | WW domain containing oxidoreductase | -0.0167794 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0166762 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0165602 |
| DST | dystonin | -0.0165142 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.016424 |
| NAV3 | neuron navigator 3 | -0.0164064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0162859 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0161195 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0159841 |
| RPS21 | ribosomal protein S21 | -0.0159629 |
| BPTF | bromodomain PHD finger transcription factor | -0.0158206 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0157901 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0157064 |
