| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0843968 |
| GOLGA4 | golgin A4 | 0.0817518 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0784627 |
| TMF1 | TATA element modulatory factor 1 | 0.0583801 |
| RPS2 | ribosomal protein S2 | 0.0567948 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.049938 |
| ZNF292 | zinc finger protein 292 | 0.0491361 |
| VMP1 | vacuole membrane protein 1 | 0.044089 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0427832 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0423889 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0422417 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0399435 |
| PCBP2 | poly(rC) binding protein 2 | 0.0397784 |
| MT2A | metallothionein 2A | 0.038049 |
| NUP58 | nucleoporin 58 | 0.0379446 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0357929 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0354715 |
| SETD5 | SET domain containing 5 | 0.0352843 |
| TXNIP | thioredoxin interacting protein | 0.0351551 |
| CCNL1 | cyclin L1 | 0.0346023 |
| KIAA1217 | KIAA1217 | 0.0334621 |
| ZNF654 | zinc finger protein 654 | 0.0330481 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0322916 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0322859 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0317897 |
| RPS12 | ribosomal protein S12 | 0.0315071 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0314912 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0313319 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0310077 |
| WDR26 | WD repeat domain 26 | 0.0307066 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0305677 |
| CENPF | centromere protein F, 350/400kDa | 0.0304467 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0304378 |
| TPR | translocated promoter region, nuclear basket protein | 0.0304364 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0296484 |
| TMEM41B | transmembrane protein 41B | 0.0295759 |
| RPL21 | ribosomal protein L21 | 0.0292911 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0283775 |
| TXNRD1 | thioredoxin reductase 1 | 0.0272304 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0271444 |
| OGA | O-GlcNAcase | 0.0262974 |
| SRP54 | signal recognition particle 54kDa | 0.0258881 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0257479 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0256131 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0253531 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0250131 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0248925 |
| RNF24 | ring finger protein 24 | 0.024892 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0245698 |
| PCM1 | pericentriolar material 1 | 0.0242192 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0240009 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0236807 |
| FAM162A | family with sequence similarity 162, member A | 0.0236645 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0232985 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0232112 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0231708 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0228572 |
| HELZ | helicase with zinc finger | 0.0227688 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0226972 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0224055 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0221651 |
| CCNC | cyclin C | 0.0221204 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0220103 |
| RBM25 | RNA binding motif protein 25 | 0.0219982 |
| ZNF638 | zinc finger protein 638 | 0.0219928 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0219267 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.021853 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0216381 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0216216 |
| TMEM87A | transmembrane protein 87A | 0.0216032 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.021532 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.021414 |
| TMEM39A | transmembrane protein 39A | 0.021238 |
| PNN | pinin, desmosome associated protein | 0.0211344 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0211071 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0211039 |
| ZFP36 | ZFP36 ring finger protein | 0.0209962 |
| DENR | density-regulated protein | 0.020972 |
| YTHDC1 | YTH domain containing 1 | 0.0209576 |
| SGO2 | shugoshin 2 | 0.0207705 |
| SUCO | SUN domain containing ossification factor | 0.0204459 |
| CDK8 | cyclin-dependent kinase 8 | 0.0201449 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0201092 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0198892 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0197081 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0196109 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0195687 |
| KLF6 | Kruppel-like factor 6 | 0.0195376 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.019537 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0194886 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0193831 |
| H1-2 | H1.2 linker histone, cluster member | 0.0193627 |
| FAM117B | family with sequence similarity 117, member B | 0.0193091 |
| FAM13A | family with sequence similarity 13, member A | 0.0192959 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0192665 |
| CEP290 | centrosomal protein 290kDa | 0.019233 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0192037 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0190818 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0190533 |
| WDR43 | WD repeat domain 43 | 0.0187843 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.242714 |
| AHNAK | AHNAK nucleoprotein | -0.19403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.172032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.171796 |
| LOC112694756 | uncharaterized LOC112694756 | -0.12933 |
| PTMA | prothymosin, alpha | -0.118458 |
| NDRG1 | N-myc downstream regulated 1 | -0.108508 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0927019 |
| TMSB10 | thymosin beta 10 | -0.0911646 |
| PKM | pyruvate kinase, muscle | -0.0886422 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0807317 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0718383 |
| CANX | calnexin | -0.0703946 |
| INTS6 | integrator complex subunit 6 | -0.0670999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.064828 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0641958 |
| KRT18 | keratin 18, type I | -0.0606889 |
| HDLBP | high density lipoprotein binding protein | -0.0601421 |
| RPL35A | ribosomal protein L35a | -0.0561177 |
| POTEF | POTE ankyrin domain family, member F | -0.0540169 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0509549 |
| CTBP2 | C-terminal binding protein 2 | -0.0500016 |
| ARF1 | ADP-ribosylation factor 1 | -0.0484909 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0481061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048074 |
| ENO1 | enolase 1, (alpha) | -0.0475284 |
| ACTG1 | actin gamma 1 | -0.0462772 |
| LDHA | lactate dehydrogenase A | -0.0459083 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0452935 |
| RPL4 | ribosomal protein L4 | -0.044969 |
| EGR1 | early growth response 1 | -0.0447982 |
| MSI2 | musashi RNA-binding protein 2 | -0.0438492 |
| PGK1 | phosphoglycerate kinase 1 | -0.0428059 |
| LRRC23 | leucine rich repeat containing 23 | -0.0427877 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0422783 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0420008 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0415605 |
| YBX1 | Y box binding protein 1 | -0.0410062 |
| CCND1 | cyclin D1 | -0.0409628 |
| KRT8 | keratin 8, type II | -0.040915 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0397509 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0392818 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0391641 |
| RPLP1 | ribosomal protein, large, P1 | -0.03913 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.038413 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.038323 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0372813 |
| SERINC5 | serine incorporator 5 | -0.0370666 |
| FHIT | fragile histidine triad | -0.0369685 |
| EGFR | epidermal growth factor receptor | -0.0368235 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0363603 |
| TENM3 | teneurin transmembrane protein 3 | -0.0357486 |
| CCDC47 | coiled-coil domain containing 47 | -0.0353524 |
| GPHN | gephyrin | -0.0346365 |
| APP | amyloid beta (A4) precursor protein | -0.0345481 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0340083 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0334902 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0333784 |
| FUS | FUS RNA binding protein | -0.0332195 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0329235 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0328815 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0328089 |
| ACTN4 | actinin, alpha 4 | -0.0327682 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.032096 |
| ASPH | aspartate beta-hydroxylase | -0.0320523 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.032011 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0318441 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0316817 |
| TMEM123 | transmembrane protein 123 | -0.0314077 |
| EZR | ezrin | -0.0307648 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0307139 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.030652 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0302542 |
| TUBA1B | tubulin, alpha 1b | -0.0299126 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0299086 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0297674 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294582 |
| EPCAM | epithelial cell adhesion molecule | -0.0291884 |
| FLNA | filamin A, alpha | -0.029138 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0287653 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0286978 |
| BPTF | bromodomain PHD finger transcription factor | -0.0286629 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0286381 |
| ANXA2 | annexin A2 | -0.0286072 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0285225 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0285049 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0282376 |
| RNF213 | ring finger protein 213 | -0.0280664 |
| CLTC | clathrin, heavy chain (Hc) | -0.0278766 |
| RCC1 | regulator of chromosome condensation 1 | -0.0277512 |
| S100A10 | S100 calcium binding protein A10 | -0.0276624 |
| WWOX | WW domain containing oxidoreductase | -0.0273399 |
| PERP | PERP, TP53 apoptosis effector | -0.0271482 |
| RPS24 | ribosomal protein S24 | -0.0271063 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0265577 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0261812 |
| SMYD3 | SET and MYND domain containing 3 | -0.026128 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0258605 |
| TGFB1 | transforming growth factor, beta 1 | -0.0257166 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0254627 |
