| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.156664 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.150146 |
| ENO1 | enolase 1, (alpha) | 0.0932705 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0903363 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0893916 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0868079 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0836289 |
| FAM13A | family with sequence similarity 13, member A | 0.0752206 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0701313 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0685182 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0676147 |
| SETD5 | SET domain containing 5 | 0.0665308 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0642291 |
| GOLGA4 | golgin A4 | 0.0614978 |
| ASPH | aspartate beta-hydroxylase | 0.0598529 |
| VIM | vimentin | 0.0566224 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0553783 |
| PTK2 | protein tyrosine kinase 2 | 0.055147 |
| RNF145 | ring finger protein 145 | 0.0535859 |
| MSN | moesin | 0.051913 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0503736 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0500666 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0500602 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0494234 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0494088 |
| RPS12 | ribosomal protein S12 | 0.0471173 |
| CENPF | centromere protein F, 350/400kDa | 0.045837 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0457603 |
| MYO10 | myosin X | 0.0453815 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0446882 |
| RPS2 | ribosomal protein S2 | 0.0443259 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0442436 |
| RPS6 | ribosomal protein S6 | 0.0437583 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.043609 |
| LAMB3 | laminin, beta 3 | 0.0429715 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0421703 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0419904 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0419271 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0417063 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0412948 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0404785 |
| DTNA | dystrobrevin, alpha | 0.0399896 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0398148 |
| MT2A | metallothionein 2A | 0.0393285 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0389342 |
| VMP1 | vacuole membrane protein 1 | 0.0387233 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0386803 |
| RPS8 | ribosomal protein S8 | 0.0382369 |
| DST | dystonin | 0.0375415 |
| STC1 | stanniocalcin 1 | 0.0374743 |
| LDHA | lactate dehydrogenase A | 0.0370783 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0368274 |
| RRM2 | ribonucleotide reductase M2 | 0.0367321 |
| TPI1 | triosephosphate isomerase 1 | 0.0366946 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0363676 |
| FOSL1 | FOS-like antigen 1 | 0.0361934 |
| RBM39 | RNA binding motif protein 39 | 0.0358641 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0357225 |
| RPL21 | ribosomal protein L21 | 0.035716 |
| ZNF292 | zinc finger protein 292 | 0.0356149 |
| SET | SET nuclear proto-oncogene | 0.0355218 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0353452 |
| ANXA5 | annexin A5 | 0.0349929 |
| RRBP1 | ribosome binding protein 1 | 0.0343176 |
| TMF1 | TATA element modulatory factor 1 | 0.0341026 |
| NUP58 | nucleoporin 58 | 0.0338628 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0332426 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.033206 |
| SEPTIN7 | septin 7 | 0.0331331 |
| KIF5B | kinesin family member 5B | 0.0329716 |
| RPL37A | ribosomal protein L37a | 0.0328999 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0328155 |
| RPL11 | ribosomal protein L11 | 0.0321365 |
| TPM3 | tropomyosin 3 | 0.031918 |
| NAV1 | neuron navigator 1 | 0.0317716 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0313946 |
| PGK1 | phosphoglycerate kinase 1 | 0.0312716 |
| ATP13A3 | ATPase type 13A3 | 0.0312232 |
| SPAG9 | sperm associated antigen 9 | 0.0311875 |
| RPLP2 | ribosomal protein, large, P2 | 0.0310287 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308677 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0307878 |
| JMJD1C | jumonji domain containing 1C | 0.0302275 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0301339 |
| RACK1 | receptor for activated C kinase 1 | 0.0298836 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0289831 |
| B2M | beta-2-microglobulin | 0.0289603 |
| H1-2 | H1.2 linker histone, cluster member | 0.0287567 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0284152 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0283842 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0283636 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0282081 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0281967 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0279339 |
| NAV2 | neuron navigator 2 | 0.0276899 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0275861 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0275852 |
| VEGFA | vascular endothelial growth factor A | 0.0274546 |
| RNF24 | ring finger protein 24 | 0.0273948 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0272569 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.123877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122263 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.121679 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0899842 |
| HMGA2 | high mobility group AT-hook 2 | -0.0870517 |
| LOX | lysyl oxidase | -0.063338 |
| IGF2 | insulin-like growth factor 2 | -0.0612711 |
| LOC112694756 | uncharaterized LOC112694756 | -0.058933 |
| EGR1 | early growth response 1 | -0.043305 |
| VCL | vinculin | -0.0416383 |
| COL5A1 | collagen, type V, alpha 1 | -0.0404231 |
| CD44 | CD44 molecule (Indian blood group) | -0.0363762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0357067 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0341538 |
| ACTN4 | actinin, alpha 4 | -0.0339083 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0335845 |
| CANX | calnexin | -0.033545 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0327084 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0300882 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0296716 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0294014 |
| TMSB10 | thymosin beta 10 | -0.0292353 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0275358 |
| IER3 | immediate early response 3 | -0.0268491 |
| PCBP3 | poly(rC) binding protein 3 | -0.0251596 |
| OSMR | oncostatin M receptor | -0.0250136 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0249283 |
| AHNAK | AHNAK nucleoprotein | -0.024312 |
| FLNA | filamin A, alpha | -0.0242311 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0233756 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0230655 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0230087 |
| RPS24 | ribosomal protein S24 | -0.0219259 |
| FTL | ferritin, light polypeptide | -0.0213426 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.020506 |
| RASA3 | RAS p21 protein activator 3 | -0.0198397 |
| NABP1 | nucleic acid binding protein 1 | -0.0194914 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0193335 |
| RPL35A | ribosomal protein L35a | -0.0188962 |
| PALLD | palladin, cytoskeletal associated protein | -0.0187864 |
| CCND1 | cyclin D1 | -0.0187104 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0185019 |
| SETX | senataxin | -0.0183892 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0180666 |
| HDLBP | high density lipoprotein binding protein | -0.0180574 |
| SEPTIN9 | septin 9 | -0.0175204 |
| TGFB1 | transforming growth factor, beta 1 | -0.0174506 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0171043 |
| PLEC | plectin | -0.0170791 |
| JUN | jun proto-oncogene | -0.0169801 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0169321 |
| INTS6 | integrator complex subunit 6 | -0.0168696 |
| STK10 | serine/threonine kinase 10 | -0.0162176 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.015971 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0158061 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0154517 |
| TXNRD1 | thioredoxin reductase 1 | -0.0152639 |
| FSTL1 | follistatin-like 1 | -0.0152532 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0150944 |
| GOLGA3 | golgin A3 | -0.0150439 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0150365 |
| ARF1 | ADP-ribosylation factor 1 | -0.0149843 |
| IL11 | interleukin 11 | -0.0149674 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0148468 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0146729 |
| RNF213 | ring finger protein 213 | -0.0146495 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0145122 |
| CMIP | c-Maf inducing protein | -0.0143288 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0142267 |
| COPA | coatomer protein complex, subunit alpha | -0.0141177 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0139745 |
| PTMA | prothymosin, alpha | -0.0138857 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0138083 |
| PDE10A | phosphodiesterase 10A | -0.0137335 |
| MT1X | metallothionein 1X | -0.0136082 |
| UBC | ubiquitin C | -0.013559 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0135535 |
| SFTPA2 | surfactant protein A2 | -0.0135281 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0133264 |
| EXT1 | exostosin glycosyltransferase 1 | -0.013166 |
| EGFR | epidermal growth factor receptor | -0.013151 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0131388 |
| TNNC1 | troponin C type 1 (slow) | -0.0130033 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0129093 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0128725 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0127325 |
| PDCD6 | programmed cell death 6 | -0.012691 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0126889 |
| THBS2 | thrombospondin 2 | -0.0126885 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0126848 |
| DUSP6 | dual specificity phosphatase 6 | -0.0126826 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0126224 |
| GPR107 | G protein-coupled receptor 107 | -0.0125789 |
| L1CAM | L1 cell adhesion molecule | -0.0125664 |
| CLIC4 | chloride intracellular channel 4 | -0.0125234 |
| METTL15 | methyltransferase like 15 | -0.0125228 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0124772 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0122721 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0120859 |
| WDR45B | WD repeat domain 45B | -0.0120037 |
