| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0511431 |
| CADM1 | cell adhesion molecule 1 | 0.0361183 |
| ATP13A3 | ATPase type 13A3 | 0.0216455 |
| QKI | QKI, KH domain containing, RNA binding | 0.0183559 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0169137 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0140899 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0123932 |
| USP3 | ubiquitin specific peptidase 3 | 0.0112255 |
| TFG | TRK-fused gene | 0.0102412 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.00928931 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00924259 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00918334 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00918124 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00913034 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00863675 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00859268 |
| RAB1A | RAB1A, member RAS oncogene family | 0.00792593 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00773673 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00756171 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00748188 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00740755 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00725055 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00715796 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00711972 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00695965 |
| RNF145 | ring finger protein 145 | 0.00691479 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00691231 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00687657 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00663161 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.00662263 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00649599 |
| CCNL1 | cyclin L1 | 0.00642637 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00641479 |
| SESN2 | sestrin 2 | 0.00635389 |
| DENND5A | DENN/MADD domain containing 5A | 0.00631907 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00631615 |
| IRF1 | interferon regulatory factor 1 | 0.00629001 |
| H1-2 | H1.2 linker histone, cluster member | 0.00626678 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.00625702 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00625022 |
| ZNF292 | zinc finger protein 292 | 0.00602474 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.0059879 |
| NUP58 | nucleoporin 58 | 0.00597398 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.005867 |
| MATR3 | matrin 3 | 0.00577126 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00566357 |
| ZFP36 | ZFP36 ring finger protein | 0.00563065 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0055505 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00545778 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00542854 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0054168 |
| WTAP | Wilms tumor 1 associated protein | 0.00541182 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00536288 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00534592 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00530173 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00522222 |
| SEC24D | SEC24 family member D | 0.00521065 |
| CLINT1 | clathrin interactor 1 | 0.00518525 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00518475 |
| TMEM39A | transmembrane protein 39A | 0.00518159 |
| COLEC11 | collectin sub-family member 11 | 0.00517091 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00504085 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0050259 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00502477 |
| SPOPL | speckle-type POZ protein-like | 0.00501793 |
| TMEM41B | transmembrane protein 41B | 0.00494228 |
| ZNF326 | zinc finger protein 326 | 0.00479997 |
| WRN | Werner syndrome, RecQ helicase-like | 0.00479238 |
| CD83 | CD83 molecule | 0.00478369 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0047709 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00476544 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00473825 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00470411 |
| CDC73 | cell division cycle 73 | 0.00458848 |
| SNX13 | sorting nexin 13 | 0.00457288 |
| BBX | bobby sox homolog (Drosophila) | 0.00454304 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00453998 |
| TES | testin LIM domain protein | 0.00453766 |
| ATN1 | atrophin 1 | 0.00453053 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.00450114 |
| MYO1B | myosin IB | 0.00447248 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.00439632 |
| MYO6 | myosin VI | 0.00438845 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00438111 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.00428067 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.00425914 |
| HBP1 | HMG-box transcription factor 1 | 0.00424993 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.00424554 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.00424524 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.00423987 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.00419826 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.00419752 |
| HELZ | helicase with zinc finger | 0.00418955 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00417934 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00417757 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00412918 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00409582 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00409055 |
| CCNT2 | cyclin T2 | 0.00408381 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0040798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.145109 |
| MT2A | metallothionein 2A | -0.143352 |
| COL6A3 | collagen, type VI, alpha 3 | -0.129635 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122296 |
| CD44 | CD44 molecule (Indian blood group) | -0.110668 |
| VIM | vimentin | -0.0921693 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0855213 |
| NDRG1 | N-myc downstream regulated 1 | -0.0763182 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0762239 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0734875 |
| COL1A1 | collagen, type I, alpha 1 | -0.0700554 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0691387 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0633471 |
| STC1 | stanniocalcin 1 | -0.0621174 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0598107 |
| LOXL2 | lysyl oxidase-like 2 | -0.0588447 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.058372 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0570192 |
| TMSB10 | thymosin beta 10 | -0.0490363 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.045658 |
| CDH13 | cadherin 13 | -0.0453857 |
| COL5A1 | collagen, type V, alpha 1 | -0.044488 |
| CALR | calreticulin | -0.0438027 |
| FBN1 | fibrillin 1 | -0.0431564 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0431053 |
| COL1A2 | collagen, type I, alpha 2 | -0.0430397 |
| ASPH | aspartate beta-hydroxylase | -0.0429498 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0406122 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.038844 |
| LDHA | lactate dehydrogenase A | -0.0377093 |
| HMGA2 | high mobility group AT-hook 2 | -0.0373737 |
| ENO1 | enolase 1, (alpha) | -0.0362542 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.036037 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.035446 |
| HLA-B | major histocompatibility complex, class I, B | -0.0334132 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0332305 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0328003 |
| RPS8 | ribosomal protein S8 | -0.0321903 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0314589 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0312564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0311203 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0310494 |
| GLIS3 | GLIS family zinc finger 3 | -0.0307227 |
| LOX | lysyl oxidase | -0.029451 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0282954 |
| NAV1 | neuron navigator 1 | -0.0282388 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0281596 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0276716 |
| ECE1 | endothelin converting enzyme 1 | -0.0275107 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0273496 |
| VEGFA | vascular endothelial growth factor A | -0.0273431 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0270644 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0268727 |
| TPM4 | tropomyosin 4 | -0.0266534 |
| FTL | ferritin, light polypeptide | -0.0263087 |
| PTMA | prothymosin, alpha | -0.0262049 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0261623 |
| B2M | beta-2-microglobulin | -0.025581 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0254851 |
| PDE10A | phosphodiesterase 10A | -0.0248523 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0247492 |
| VCAN | versican | -0.0244857 |
| RUNX1 | runt-related transcription factor 1 | -0.0244123 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0243625 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0243155 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0241159 |
| CALU | calumenin | -0.0234565 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0234349 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0233123 |
| PRELID2 | PRELI domain containing 2 | -0.0232468 |
| AHNAK | AHNAK nucleoprotein | -0.0231308 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0229761 |
| SDC2 | syndecan 2 | -0.0227615 |
| MAP1B | microtubule-associated protein 1B | -0.0227369 |
| RRBP1 | ribosome binding protein 1 | -0.0224897 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0222727 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0222132 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0220921 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.022044 |
| CANX | calnexin | -0.0219266 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021229 |
| MT1X | metallothionein 1X | -0.0210875 |
| CTSB | cathepsin B | -0.0210153 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0209802 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0209086 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0208857 |
| S100A9 | S100 calcium binding protein A9 | -0.0206744 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0206454 |
| TMSB4X | thymosin beta 4, X-linked | -0.0198239 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0198204 |
| SMAD3 | SMAD family member 3 | -0.0196821 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0196639 |
| RPS19 | ribosomal protein S19 | -0.0193804 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0190089 |
| PLEC | plectin | -0.0189876 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0187103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0186404 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.018522 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0182407 |
| HAS2 | hyaluronan synthase 2 | -0.0181266 |
